ZO-2 favors Hippo signaling, and its re-expression in the steatotic liver by AMPK restores junctional sealing [0.03%]
ZO-2有利于Hippo信号传导，并且在脂肪变性肝脏中被AMPK重新表达以恢复连接处的密封功能
Laura González-González,Helios Gallego-Gutiérrez,Dolores Martin-Tapia et al.
Laura González-González et al.
ZO-2 is a peripheral tight junction (TJ) protein whose silencing in renal epithelia induces cell hypertrophy. Here, we found that in ZO-2 KD MDCK cells, in compensatory renal hypertrophy triggered in rats by a unilateral nephrectomy and in ...
Treatment of acute wounds in hand with Calendula officinalis L.: A randomized trial [0.03%]
金盏花在手部急性伤口治疗中的应用:一项随机试验
Giana Silveira Giostri,Eduardo Murilo Novak,Marcelo Buzzi et al.
Giana Silveira Giostri et al.
Most injuries in the hand and fingers, especially on the digital pulps, are suited for healing by secondary intention. Nevertheless, delay in epithelization seems to unfavorably restrict this technique. The purpose of this controlled random...
Randomized Controlled Trial
Tissue barriers. 2022 Jul 3;10(3):1994822. DOI:10.1080/21688370.2021.1994822 2022
Sarmistha Talukdar,Luni Emdad,Swadesh K Das et al.
Sarmistha Talukdar et al.
Gap junctions are intercellular membrane channels consisting of connexin proteins, which contribute to direct cytoplasmic exchange of small molecules, substrates and metabolites between adjacent cells. These channels play important roles in...
Potential Protective Effect of Spirulina Platensis on Sodium Arsenite Induced Cardiotoxicity in Male Rats [0.03%]
螺旋藻对雄性大鼠钠砷诱导的心脏毒性的潜在保护作用
Amal Albtoosh,Fardous Karawya,Wesam Al-Naymat et al.
Amal Albtoosh et al.
Background: Sodium arsenite is a dangerous bio-accumulative poison affecting a large number of people as well as animals throughout the world. It is used clinically in the treatment of certain medical conditions, but due ...
Role of mononuclear stem cells and decellularized amniotic membrane in the treatment of skin wounds in rats [0.03%]
单核干细胞和脱细胞的羊膜在大鼠皮肤创伤治疗中的作用
Aline L Takejima,Julio C Francisco,Rossana B Simeoni et al.
Aline L Takejima et al.
Stem cells (SC) and amniotic membrane (AM) are recognized for their beneficial impacts on the healing of cutaneous wounds. Thus, this study evaluated the capacity of tissue repair in a skin lesion rat model. Forty Wistar rats were randomize...
DCE-MRI of Brain Fluid Barriers: In Vivo Water Cycling at the Human Choroid Plexus [0.03%]
脑液体屏障的DCE-MRI：人类脉络丛中的水循环
Valerie C Anderson,Ian J Tagge,Aaron Doud et al.
Valerie C Anderson et al.
Metabolic deficits at brain-fluid barriers are an increasingly recognized feature of cognitive decline in older adults. At the blood-cerebrospinal fluid barrier, water is transported across the choroid plexus (CP) epithelium against large o...
S1P in the development of atherosclerosis: roles of hemodynamic wall shear stress and endothelial permeability [0.03%]
S1P在动脉粥样硬化发展中的作用：血流动力学壁剪应力和内皮通透性的作用
Christina M Warboys,Peter D Weinberg
Christina M Warboys
Atherosclerosis is characterized by focal accumulations of lipid within the arterial wall, thought to arise from effects of hemodynamic wall shear stress (WSS) on endothelial permeability. Identifying pathways that mediate the effects of sh...
Dysfunction of epithelial permeability barrier induced by HMGB1 in 2.5D cultures of human epithelial cells [0.03%]
HMGB1在人上皮细胞的2.5D培养中对上皮渗透性屏障功能障碍的影响
Takashi Kojima,Yuma Shindo,Takumi Konno et al.
Takashi Kojima et al.
Airway and intestinal epithelial permeability barriers are crucial in epithelial homeostasis. High mobility group box 1 (HMGB1), increased by various stimuli, is involved in the induction of airway inflammation, as well as the pathogenesis ...
Altered expression of junctional proteins as a potential biomarker in oral precancerous and cancerous patients [0.03%]
口腔癌前病变和癌变患者连接蛋白表达改变作为潜在生物标志物的作用
Puja Upadhaya,Sarbani Giri,Dharmeswar Barhoi et al.
Puja Upadhaya et al.
Due to a lower survival rate in patients with advanced clinical stages of oral cancer, discovering a biomarker that could diagnose and predict disease progression is vital. Cell-cell junctional proteins play a crucial role in the maintenanc...
Protease-activated receptor-2 activation enhances epithelial wound healing via epidermal growth factor receptor [0.03%]
蛋白酶激活受体-2通过表皮生长因子受体促进上皮伤口愈合
Mahesha Bandara,Wallace K MacNaughton
Mahesha Bandara
The intestinal barrier function relies on the presence of a single layer of epithelial cells. Barrier dysfunction is associated with the inflammatory bowel diseases (IBD). Understanding the mechanisms involved in intestinal wound healing in...