MMP9 expression in intestinal fistula from patients with fistulizing CD and from human xenograft mouse model [0.03%]
来自人类异种移植小鼠模型的肠 Fistulas 的 MMP9 表达来自患有瘘管型 CD 的患者
Céline Mamie,Ramona S Bruckner,Silvia Lang et al.
Céline Mamie et al.
Fistula treatment represents a major unmet medical need in the therapy of Crohn's disease (CD). Current medical therapies, such as anti-TNF antibody treatments, are often insufficient and do not achieve permanent fistula closure. Previously...
Biotherapeutic effect of cell-penetrating peptides against microbial agents: a review [0.03%]
穿膜肽对微生物剂的生物治疗作用：一项综述
Idris Zubairu Sadiq,Aliyu Muhammad,Sanusi Bello Mada et al.
Idris Zubairu Sadiq et al.
Selective permeability of biological membranes represents a significant barrier to the delivery of therapeutic substances into both microorganisms and mammalian cells, restricting the access of drugs into intracellular pathogens. Cell-penet...
Urinary IgG, serum CX3CL1 and miRNA-152-3p: as predictors of nephropathy in Egyptian type 2 diabetic patients [0.03%]
尿IgG，血清CX3CL1和miRNA-152-3p：作为埃及二型糖尿病患者肾病的预测因子
Aml E Abdou,Haneya A A Anani,Hanan F Ibrahim et al.
Aml E Abdou et al.
The purpose of this study was to assess the role of urinary IgG, serum CX3CL1 and miRNA 152-3p levels as predictors of nephropathy in type 2 Egyptian diabetic patients. Sixty type 2 diabetic patients and twenty healthy controls were enrolle...
ZO-2 favors Hippo signaling, and its re-expression in the steatotic liver by AMPK restores junctional sealing [0.03%]
ZO-2有利于Hippo信号传导，并且在脂肪变性肝脏中被AMPK重新表达以恢复连接处的密封功能
Laura González-González,Helios Gallego-Gutiérrez,Dolores Martin-Tapia et al.
Laura González-González et al.
ZO-2 is a peripheral tight junction (TJ) protein whose silencing in renal epithelia induces cell hypertrophy. Here, we found that in ZO-2 KD MDCK cells, in compensatory renal hypertrophy triggered in rats by a unilateral nephrectomy and in ...
Treatment of acute wounds in hand with Calendula officinalis L.: A randomized trial [0.03%]
金盏花在手部急性伤口治疗中的应用:一项随机试验
Giana Silveira Giostri,Eduardo Murilo Novak,Marcelo Buzzi et al.
Giana Silveira Giostri et al.
Most injuries in the hand and fingers, especially on the digital pulps, are suited for healing by secondary intention. Nevertheless, delay in epithelization seems to unfavorably restrict this technique. The purpose of this controlled random...
Randomized Controlled Trial
Tissue barriers. 2022 Jul 3;10(3):1994822. DOI:10.1080/21688370.2021.1994822 2022
Sarmistha Talukdar,Luni Emdad,Swadesh K Das et al.
Sarmistha Talukdar et al.
Gap junctions are intercellular membrane channels consisting of connexin proteins, which contribute to direct cytoplasmic exchange of small molecules, substrates and metabolites between adjacent cells. These channels play important roles in...
Potential Protective Effect of Spirulina Platensis on Sodium Arsenite Induced Cardiotoxicity in Male Rats [0.03%]
螺旋藻对雄性大鼠钠砷诱导的心脏毒性的潜在保护作用
Amal Albtoosh,Fardous Karawya,Wesam Al-Naymat et al.
Amal Albtoosh et al.
Background: Sodium arsenite is a dangerous bio-accumulative poison affecting a large number of people as well as animals throughout the world. It is used clinically in the treatment of certain medical conditions, but due ...
Role of mononuclear stem cells and decellularized amniotic membrane in the treatment of skin wounds in rats [0.03%]
单核干细胞和脱细胞的羊膜在大鼠皮肤创伤治疗中的作用
Aline L Takejima,Julio C Francisco,Rossana B Simeoni et al.
Aline L Takejima et al.
Stem cells (SC) and amniotic membrane (AM) are recognized for their beneficial impacts on the healing of cutaneous wounds. Thus, this study evaluated the capacity of tissue repair in a skin lesion rat model. Forty Wistar rats were randomize...
DCE-MRI of Brain Fluid Barriers: In Vivo Water Cycling at the Human Choroid Plexus [0.03%]
脑液体屏障的DCE-MRI：人类脉络丛中的水循环
Valerie C Anderson,Ian J Tagge,Aaron Doud et al.
Valerie C Anderson et al.
Metabolic deficits at brain-fluid barriers are an increasingly recognized feature of cognitive decline in older adults. At the blood-cerebrospinal fluid barrier, water is transported across the choroid plexus (CP) epithelium against large o...
S1P in the development of atherosclerosis: roles of hemodynamic wall shear stress and endothelial permeability [0.03%]
S1P在动脉粥样硬化发展中的作用：血流动力学壁剪应力和内皮通透性的作用
Christina M Warboys,Peter D Weinberg
Christina M Warboys
Atherosclerosis is characterized by focal accumulations of lipid within the arterial wall, thought to arise from effects of hemodynamic wall shear stress (WSS) on endothelial permeability. Identifying pathways that mediate the effects of sh...