Membrane lipid composition of bronchial epithelial cells influences antiviral responses during rhinovirus infection [0.03%]
支气管上皮细胞的膜脂组成影响鼻病毒感染期间的抗病毒反应
Madhuriben H Panchal,Emily J Swindle,Theresa J Pell et al.
Madhuriben H Panchal et al.
Lipids and their mediators have important regulatory functions in many cellular processes, including the innate antiviral response. The aim of this study was to compare the lipid membrane composition of in vitro differentiated primary bronc...
8-Bromo-cAMP attenuates human airway epithelial barrier disruption caused by titanium dioxide fine and nanoparticles [0.03%]
8-溴-cAMP减轻由二氧化钛细颗粒和纳米颗粒造成的对人呼吸道上皮屏障的破坏
Claire E Lee,Andjela Raduka,Nannan Gao et al.
Claire E Lee et al.
Titanium dioxide fine particles (TiO2-FPs) and nanoparticles (TiO2-NPs) are the most widely used whitening pigments worldwide. Inhalation of TiO2-FPs and TiO2-NPs can be harmful as it triggers toxicity in the airway epithelial cells. The ai...
Brain uptake pharmacokinetics of albiglutide, dulaglutide, tirzepatide, and DA5-CH in the search for new treatments of Alzheimer's and Parkinson's diseases [0.03%]
阿尔茨海默病和帕金森病新疗法研究中奥格利lutide、杜拉lutide、替扎patide和DA5-CH的脑摄取药代动力学
Elizabeth M Rhea,Alice Babin,Peter Thomas et al.
Elizabeth M Rhea et al.
Background: A number of peptide incretin receptor agonists (IRAs) show promise as therapeutics for Alzheimer's disease (AD) and Parkinson's disease (PD). Transport across the blood-brain barrier (BBB) is one way for IRAs ...
Effect of Bevacizumab on traumatic penumbra brain edema in rats at different time points [0.03%]
贝伐单抗对不同时间点颅脑损伤缺血半暗带脑水肿的影响研究
Li Ai,Chen Xin,Muhammad Usman et al.
Li Ai et al.
Traumatic penumbra (TP) is a secondary injury area located around the core area of traumatic brain injury after brain trauma, and is an important factor affecting the outcome of traumatic brain injury (TBI). The main pathological change cau...
Surface layer proteins from Lactobacillus helveticus ATCC® 15009™ affect the gut barrier morphology and function [0.03%]
乳酸菌Lactobacillus helveticus ATCC® 15009™的表面蛋白影响肠道屏障形态和功能
Paola Bendinelli,Ivano De Noni,Stefano Cattaneo et al.
Paola Bendinelli et al.
Paraprobiotics and postbiotics represent a valid alternative to probiotic strains for ameliorating and preserving a healthy intestinal epithelial barrier (IEB). The present study investigated the effects of surface layer proteins (S-layer) ...
Decellularized small intestine scaffolds: a potential xenograft for restoration of intestinal perforation [0.03%]
脱细胞小肠支架：一种潜在的异种移植物以修复肠道穿孔
Kishor Tardalkar,Sonal Patil,Leena Chaudhari et al.
Kishor Tardalkar et al.
Small intestine perforation is a serious medical condition that requires immediate medical attention. The traditional course of treatment entails resection followed by anastomosis; however, it has complications such as small bowel syndrome ...
Curative role of natural PPARγ agonist in non-alcoholic fatty liver disease (NAFLD) [0.03%]
天然PPARγ激动剂在非酒精性脂肪肝病（NAFLD）中发挥治愈作用
Swati Singh,Anit Kumar,Suruchi Gupta et al.
Swati Singh et al.
NAFLD is a condition that develops when the liver accumulates excess fat without alcohol consumption. This chronic liver ailment progresses along with insulin resistant and is typically not diagnosed until the patients have cirrhosis. Nucle...
The amazing axolotl: robust kidney regeneration following acute kidney injury [0.03%]
阿维尔特鳚的肾脏在急性肾损伤后的再生能力研究
Elysa Ng May May,Rebecca A Wingert
Elysa Ng May May
The incidence of kidney disease from acute and chronic conditions continues to escalate worldwide. Interventions to replace renal function after organ failure remain limited to dialysis or transplantation, as human kidneys exhibit a limited...
Forever young by Alpha(diversity)ville: restricting intestinal microbiome maturation stunts immune system development and increases susceptibility to infection [0.03%]
永远年轻：限制肠道微生物群成熟阻碍免疫系统发育并增加感染易感性
Dorrian G Cohen,Rebecca A Wingert
Dorrian G Cohen
The microbiome is a keystone of adult gastrointestinal (GI) tract health, where it facilitates digestion, wards off pathogen colonization, and exerts a powerful influence on the physiological health of organs ranging from the brain to the k...
Canadine inhibits epithelial mesenchymal transformation of HPV-negative cervical cancer [0.03%]
-canadine通过抑制上皮间质转化抑制人乳头瘤病毒阴性的宫颈癌细胞的侵袭和迁移作用
Yan Ma,Qian-Qian Yang,Dong-Mei Gu et al.
Yan Ma et al.
Although the majority of the population will be protected due to the advent and widespread use of the HPV vaccine, the treatment of cervical cancer for all causes, including HPV-negative cervical cancer, is still worthy of further research....