Challenges in the Design, Registration, and Reporting of Noninferiority Trials [0.03%]
非劣性试验的设计、注册和报告面临的挑战
Rolf H H Groenwold,Eibert R Heerdink,Olaf H Klungel
Rolf H H Groenwold
Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials [0.03%]
不符合随机临床试验条件的精神分裂症患者的特征及其预后状况日常门诊精神分裂症患者的特点及结局——来自常规临床实践的证据
Heidi Taipale,Johannes Schneider-Thoma,Justo Pinzón-Espinosa et al.
Heidi Taipale et al.
Importance: Most evidence about efficacy and safety of antipsychotics in schizophrenia spectrum disorders relies on randomized clinical trials (RCTs). However, owing to their strict eligibility criteria, RCTs represent on...
Community-Level Social Support Infrastructure and Adult Onset of Major Depressive Disorder in a South Asian Postconflict Setting [0.03%]
社区级社会支持基础设施与南亚冲突后背景下的成人期抑郁症发病的关系研究
William G Axinn,Karmel W Choi,Dirgha J Ghimire et al.
William G Axinn et al.
Importance: Individual-level social support protects against major depressive disorder (MDD) among adults exposed to trauma. Little is known about the consequences of community-level interventions in the general populatio...
Published Erratum
JAMA psychiatry. 2022 Mar 1;79(3):272. DOI:10.1001/jamapsychiatry.2021.4321 2022
Maintenance of Wellness in Patients With Obsessive-Compulsive Disorder Who Discontinue Medication After Exposure/Response Prevention Augmentation: A Randomized Clinical Trial [0.03%]
暴露反应预防增效治疗后奥迫症患者停用药物后的保健维持：随机临床试验
Edna B Foa,Helen Blair Simpson,Thea Gallagher et al.
Edna B Foa et al.
Importance: Serotonin reuptake inhibitors (SRIs) are the only medications approved for obsessive-compulsive disorder (OCD), yet most patients taking SRIs exhibit significant symptoms. Adding exposure/response prevention (...
Randomized Controlled Trial
JAMA psychiatry. 2022 Mar 1;79(3):193-200. DOI:10.1001/jamapsychiatry.2021.3997 2022
Clinical Characterization of Copy Number Variants Associated With Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank [0.03%]
基于大规模多祖先生物银行的神经发育障碍相关拷贝数变异的临床特征分析
Rebecca Birnbaum,Behrang Mahjani,Ruth J F Loos et al.
Rebecca Birnbaum et al.
Importance: Past studies identified rare copy number variants (CNVs) as risk factors for neurodevelopmental disorders (NDDs), including autism spectrum disorder and schizophrenia. However, the clinical characterization of...
Driving Performance and Cannabis Users' Perception of Safety: A Randomized Clinical Trial [0.03%]
驾驶性能与大麻使用者的安全感知：随机临床试验
Thomas D Marcotte,Anya Umlauf,David J Grelotti et al.
Thomas D Marcotte et al.
Importance: Expanding cannabis medicalization and legalization increases the urgency to understand the factors associated with acute driving impairment. O...
Randomized Controlled Trial
JAMA psychiatry. 2022 Mar 1;79(3):201-209. DOI:10.1001/jamapsychiatry.2021.4037 2022
Joshua Phelps,Ravi N Shah,Jeffrey A Lieberman
Joshua Phelps
Dissimilar Control Interventions in Clinical Trials Undermine Interpretability-Reply [0.03%]
临床试验中的不同控制干预措施损害了可解释性——回复文章
Yoni K Ashar,Tor D Wager
Yoni K Ashar
Dissimilar Control Interventions in Clinical Trials Undermine Interpretability [0.03%]
临床试验中的不同控制干预措施损害了可解释性
David Hohenschurz-Schmidt,Jerry Draper-Rodi,Lene Vase
David Hohenschurz-Schmidt