Hui Wang,Krisztina D László
Hui Wang
Importance: Parental mental disorders are associated with increased risks of infant mortality and with several developmental, mental, and somatic health outcomes, yet their associations with long-term morality in offsprin...
Precision Assignment to Psychosocial Interventions for Late-Life Depression: An Automated Treatment Decision Rule [0.03%]
精准分配心理社会干预措施治疗晚发抑郁症：一种自动化的治疗决策规则
Nili Solomonov,Daniel Kerchner,Oded Bein et al.
Nili Solomonov et al.
Importance: Most older adults with depression lack access to efficacious psychotherapies due to a critical clinician shortage. Even when treated, response rates are limited to approximately 50%. A treatment decision rule ...
Regional Specificity of Cortical Layer 3 Dendritic Spine Deficits in Schizophrenia [0.03%]
精神分裂症患者大脑皮层第3层树突棘缺陷的环区特异性研究
Kenneth N Fish,Robert A Sweet,Matthew L MacDonald et al.
Kenneth N Fish et al.
Importance: Schizophrenia (SZ) is characterized by deficits in visual-spatial working memory, a function dependent on a distributed cortical network that includes nodes in the primary visual (V1), posterior parietal (PPC)...
New Reduced Drinking Goals in Alcohol Pharmacotherapy Trials-A Novel Public-Private Effort and FDA Approval Process [0.03%]
酒精药物治疗试验中的新型减量目标及产学研合作和FDA的审批流程
Raymond F Anton,Stephanie S O&#x;Malley,Karl Mann et al.
Raymond F Anton et al.
Reductions in World Health Organization Risk Drinking Levels as a Primary Efficacy End Point for Alcohol Clinical Trials: A Review [0.03%]
世界卫生组织饮酒危险水平降低作为酒精临床试验主要疗效终点的有效性综述
Katie Witkiewitz,Raymond F Anton,Stephanie S O&#x;Malley et al.
Katie Witkiewitz et al.
Importance: Alcohol use disorder (AUD) is a highly prevalent and costly psychiatric disorder. Abstinence has been considered the optimal outcome of treatment for AUD. Yet, most individuals with AUD do not seek treatment b...
National Trends in Inpatient Psychiatric Bed Supply, 2011 to 2023 [0.03%]
2011至2023年美国住院精神病床供应量的全国趋势
Karen Shen,Mark Olfson,Adam Sacarny
Karen Shen
Neurofilament Light Chain and Differentiation of Behavioral Variant Frontotemporal Dementia From Psychiatric Disorders: A Systematic Review [0.03%]
神经丝轻链和行为变异型额颞叶痴呆与精神疾病鉴别：系统性综述
Dimitry S Davydow,Morgan Brasfield,Christopher B Morrow et al.
Dimitry S Davydow et al.
Importance: Behavioral variant frontotemporal dementia (bvFTD), the most common subtype of FTD, is a leading form of early-onset dementia worldwide. Accurate and timely diagnosis of bvFTD is frequently delayed due to symp...
High-Intensity Exercise and Hippocampal Integrity in Adults With Cannabis Use Disorder: A Randomized Clinical Trial [0.03%]
高强度锻炼对大麻使用障碍成人海马结构的影响：随机临床试验
Karyn E Richardson,Chao Suo,Lucy Albertella et al.
Karyn E Richardson et al.
Importance: Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity i...
Josh Nguyen,Dominic B Dwyer,Barnaby Nelson et al.
Josh Nguyen et al.
ANK3 as a Novel Genetic Biomarker for Liafensine in Treatment-Resistant Depression: The ENLIGHTEN Randomized Clinical Trial [0.03%]
ANK3作为难治性抑郁症对联芬辛治疗反应的新型遗传生物标志物：ENLIGHTEN随机临床试验
Gang Wang,Mario Aguado,Matthew A Spear et al.
Gang Wang et al.
Importance: This study represents a first successful use of a genetic biomarker to select potential responders in a prospective study in psychiatry. Liafensine, a triple reuptake inhibitor, may become a new precision medi...