Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis [0.03%]
肠-脑轴在胃肠道疾病与精神障碍的共病遗传病因中的作用：全基因组多效性分析
Weiming Gong,Ping Guo,Yuanming Li et al.
Weiming Gong et al.
Importance: Comorbidities and genetic correlations between gastrointestinal tract diseases and psychiatric disorders have been widely reported, with the gut-brain axis (GBA) hypothesized as a potential biological basis. H...
Association of Familial Aggregation of Major Depression With Risk of Major Depression [0.03%]
抑郁症家族聚集与重大抑郁障碍发病风险的关联研究
Frederikke Hørdam Gronemann,Rikke Kart Jacobsen,Marie Kim Wium-Andersen et al.
Frederikke Hørdam Gronemann et al.
Importance: Major depression (MD) aggregates within families, but how family history of MD confers risk of MD over the life course is unclear. Such knowledge is important to identify and prevent possible depressogenic eff...
Serotonin 4 Receptor Brain Binding in Major Depressive Disorder and Association With Memory Dysfunction [0.03%]
抑郁症患者的血清素4受体脑结合与记忆障碍的关系
Kristin Köhler-Forsberg,Vibeke H Dam,Brice Ozenne et al.
Kristin Köhler-Forsberg et al.
Importance: The cerebral serotonin 4 (5-HT4) receptor is a promising novel target for treatment of major depressive disorder (MDD), and pharmacological stimulation of the 5-HT4 receptor has been associated with improved l...
Katherine L Wisner,Paul S Appelbaum
Katherine L Wisner
Etiology of the Broad Avoidant Restrictive Food Intake Disorder Phenotype in Swedish Twins Aged 6 to 12 Years [0.03%]
瑞典6至12岁双胞胎广泛性回避限制性食物摄入障碍表型的病因学研究
Lisa Dinkler,Marie-Louis Wronski,Paul Lichtenstein et al.
Lisa Dinkler et al.
Importance: Avoidant restrictive food intake disorder (ARFID) is characterized by an extremely limited range and/or amount of food eaten, resulting in the persistent failure to meet nutritional and/or energy needs. Its et...
Obsessive-Compulsive Disorder and Its Cross-Generational Familial Association With Anxiety Disorders in a National Swedish Extended Adoption Study [0.03%]
一项国家级瑞典扩展收养研究中的强迫症及其与焦虑障碍的跨代家族关联
Kenneth S Kendler,Linda Abrahamsson,Henrik Ohlsson et al.
Kenneth S Kendler et al.
Importance: We know little about the transmission of obsessive-compulsive disorder (OCD) across generations. Objective: To evaluate the...
Long-term Exposure to Multiple Ambient Air Pollutants and Association With Incident Depression and Anxiety [0.03%]
长期暴露于多种大气污染物与抑郁症和焦虑症的关联研究
Teng Yang,Jiawei Wang,Jing Huang et al.
Teng Yang et al.
Importance: Air pollution is increasingly recognized as an important environmental risk factor for mental health. However, epidemiologic evidence on long-term exposure to low levels of air pollutants with incident depress...
Association of Primary Immunodeficiencies in Parents With Psychiatric Disorders and Suicidal Behavior in Their Offspring [0.03%]
父母原发性免疫缺陷与后代精神障碍和自杀行为的关联研究
Josef Isung,Kayoko Isomura,Kyle Williams et al.
Josef Isung et al.
Importance: Maternal immune activation (MIA) leading to altered neurodevelopment in utero is a hypothesized risk factor for psychiatric outcomes in offspring. Primary antibody immunodeficiencies (PIDs) constitute a unique...
Addressing Dementia-Related Behaviors Before, During, and After the Pandemic-Disrupting the Behavior-to-Prescribing Reflex [0.03%]
新冠疫情前后应对痴呆相关行为——打破行为与开药的连锁反应
Helen C Kales,Donovan T Maust,Laura N Gitlin
Helen C Kales
Rates of Antipsychotic Drug Prescribing Among People Living With Dementia During the COVID-19 Pandemic [0.03%]
2019冠状病毒病大流行期间痴呆患者抗精神病药物处方率的变化趋势分析
Hao Luo,Wallis C Y Lau,Yi Chai et al.
Hao Luo et al.
Importance: Concerns have been raised that the use of antipsychotic medication for people living with dementia might have increased during the COVID-19 pandemic. ...