Pharmacologic Treatment of Schizophrenia Beyond Dopamine Receptor Blockade-Has Its Time Come Yet? [0.03%]
抗精神病药物治疗不仅仅是多巴胺受体阻断剂的作用时代到来了吗？
Christoph U Correll,Leslie Citrome
Christoph U Correll
All-Cause and Cause-Specific Mortality Among Individuals With Hypochondriasis [0.03%]
疑病症患者的全因及单因素死亡率
David Mataix-Cols,Kayoko Isomura,Anna Sidorchuk et al.
David Mataix-Cols et al.
Importance: Hypochondriasis, also known as health anxiety disorder, is a prevalent, yet underdiagnosed psychiatric disorder characterized by persistent preoccupation about having serious and progressive physical disorders...
Telehealth Mindfulness-Oriented Recovery Enhancement vs Usual Care in Individuals With Opioid Use Disorder and Pain: A Randomized Clinical Trial [0.03%]
针对阿片类药物使用障碍伴疼痛患者的心理康复远程增强型治疗与常规照护的随机临床试验
Nina A Cooperman,Shou-En Lu,Adam W Hanley et al.
Nina A Cooperman et al.
Importance: Methadone treatment (MT) fails to address the emotion dysregulation, pain, and reward processing deficits that often drive opioid use disorder (OUD). New interventions are needed to address these factors. ...
Randomized Controlled Trial
JAMA psychiatry. 2024 Apr 1;81(4):338-346. DOI:10.1001/jamapsychiatry.2023.5138 2024
Clinical Outcomes of Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode: A Randomized Clinical Trial [0.03%]
磁化 seizure治疗与电休克治疗重度抑郁发作的临床疗效比较：一项随机临床试验
Zhi-De Deng,Bruce Luber,Shawn M McClintock et al.
Zhi-De Deng et al.
Importance: Electroconvulsive therapy (ECT) is highly effective and rapid in treating depression, but it carries a risk of significant cognitive adverse effects. Magnetic seizure therapy (MST), an investigational antidepr...
Randomized Controlled Trial
JAMA psychiatry. 2024 Mar 1;81(3):240-249. DOI:10.1001/jamapsychiatry.2023.4599 2024
Addressing State-Based Differences in Suicide Fatalities Among Children and Adolescents-Finding Another Way [0.03%]
儿童和青少年自杀死亡的州差异及其应对——另辟蹊径
Cordelia Mannix,Rebekah Mannix
Cordelia Mannix
Single-Dose Synthetic Psilocybin With Psychotherapy for Treatment-Resistant Bipolar Type II Major Depressive Episodes: A Nonrandomized Open-Label Trial [0.03%]
用于难治性二期双相情感障碍型重度抑郁发作的单剂量合成裸盖菇素联合心理治疗：一项非随机化、开放标记试验
Scott T Aaronson,Andrew van der Vaart,Tammy Miller et al.
Scott T Aaronson et al.
Importance: Bipolar II disorder (BDII) is a debilitating condition frequently associated with difficult-to-treat depressive episodes. Psilocybin has evidence for rapid-acting antidepressant effects but has not been invest...
Clinical Trial
JAMA psychiatry. 2024 Jun 1;81(6):555-562. DOI:10.1001/jamapsychiatry.2023.4685 2024
Psilocybin in Bipolar II Study Provides Preliminary Data on Safety [0.03%]
裸盖菇素治疗双向情感障碍II型研究提供了初步的安全性数据
David B Yaden,Natalie Gukasyan,Sandeep M Nayak
David B Yaden
Randomized Controlled Trial
JAMA psychiatry. 2024 Jun 1;81(6):541-542. DOI:10.1001/jamapsychiatry.2023.4680 2024
Accurate Machine Learning Prediction in Psychiatry Needs the Right Kind of Information [0.03%]
精神病学中准确的机器学习预测需要正确的信息类型
Brian Kraus,Kruthika Sampathgiri,Vijay A Mittal
Brian Kraus
Wayne A Ray,D Catherine Fuchs,Mark Olfson et al.
Wayne A Ray et al.
Importance: Dose-related effects of antipsychotic medications may increase mortality in children and young adults. Objective: To compar...
Transdiagnostic Ecological Momentary Intervention for Improving Self-Esteem in Youth Exposed to Childhood Adversity: The SELFIE Randomized Clinical Trial [0.03%]
针对童年逆境暴露者的跨诊断生态瞬时干预以改善青年自尊的SELFIE随机临床试验
Ulrich Reininghaus,Maud Daemen,Mary Rose Postma et al.
Ulrich Reininghaus et al.
Importance: Targeting low self-esteem in youth exposed to childhood adversity is a promising strategy for preventing adult mental disorders. Ecological momentary interventions (EMIs) allow for the delivery of youth-friend...
Randomized Controlled Trial
JAMA psychiatry. 2024 Mar 1;81(3):227-239. DOI:10.1001/jamapsychiatry.2023.4590 2024