Neuroinflammation, Stress-Related Suicidal Ideation, and Negative Mood in Depression [0.03%]
抑郁症中的神经炎症、应激相关自杀意念和负面情绪
Sarah Herzog,Elizabeth A Bartlett,Francesca Zanderigo et al.
Sarah Herzog et al.
Importance: Brain translocator protein 18k Da (TSPO) binding, a putative marker of neuroinflammatory processes (eg, gliosis), is associated with stress and elevated in depressed and suicidal populations. However, it is un...
Psychosis Spectrum Symptoms Before and After Adolescent Cannabis Use Initiation [0.03%]
青少年开始使用大麻前后的精神病谱系症状
K Juston Osborne,Deanna M Barch,Joshua J Jackson et al.
K Juston Osborne et al.
Importance: Adolescent cannabis use has been consistently posited to contribute to the onset and progression of psychosis. However, alternative causal models may account for observed associations between cannabis use and ...
Onomeasike Ataga,Valerie K Arnold
Onomeasike Ataga
Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans [0.03%]
美国退伍军人的创伤后应激障碍、肥胖症和表观遗传学衰老加速现象之间的关系
Ian C Fischer,Peter J Na,Sheila T Nagamatsu et al.
Ian C Fischer et al.
Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment: A Randomized Clinical Trial [0.03%]
重度抑郁障碍和轻度认知障碍患者认知衰退的延缓：随机临床试验
Tarek K Rajji,Christopher R Bowie,Nathan Herrmann et al.
Tarek K Rajji et al.
Importance: Older adults with major depressive disorder (MDD) or mild cognitive impairment (MCI) are at high risk for cognitive decline. Objective: ...
Randomized Controlled Trial
JAMA psychiatry. 2025 Jan 1;82(1):12-21. DOI:10.1001/jamapsychiatry.2024.3241 2025
Sexual Trauma, Polygenic Scores, and Mental Health Diagnoses and Outcomes [0.03%]
性侵犯、多基因得分与精神健康诊断和结果的关系研究
Allison M Lake,Yu Zhou,Bo Wang et al.
Allison M Lake et al.
Importance: Leveraging real-world clinical biobanks to investigate the associations between genetic and environmental risk factors for mental illness may help direct clinical screening efforts and evaluate the portability...
Manasi Kumar,Jennifer Mootz,Myrna Weissman
Manasi Kumar
Felix Teufel,Aastha Aggarwal,Lydia Chwastiak et al.
Felix Teufel et al.
Importance: Depression is a leading contributor to mental health burdens globally and in India, the world's most populous country. National-level evidence on health coverage for adults with depression in India is lacking....
Traumatic and Adverse Childhood Experiences and Developmental Differences in Psychiatric Risk [0.03%]
创伤和童年不良经历与精神病风险的发育差异
Justin D Russell,Sara A Heyn,Matthew Peverill et al.
Justin D Russell et al.
Importance: While adverse childhood experiences (ACEs) are known to impart significant risk for negative mental health and cognitive outcomes in youth, translation of ACE scores into clinical intervention is limited by po...