Esketamine Combined With SSRI or SNRI for Treatment-Resistant Depression [0.03%]
艾司氯胺酮联合SSRI或SNRI治疗难治性抑郁症
Antonio Del Casale,Sara Spirito,Jan Francesco Arena et al.
Antonio Del Casale et al.
Importance: Treatment-resistant depression (TRD) remains a critical challenge in psychiatry, with limited effective options. Esketamine, a rapid-acting antidepressant, is usually combined with a selective serotonin reupta...
Functional vs Structural Cortical Deficit Pattern Biomarkers for Major Depressive Disorder [0.03%]
用于抑郁症的功能性与结构性皮层缺陷模式生物标志物
Peter Kochunov,Bhim M Adhikari,David Keator et al.
Peter Kochunov et al.
Importance: Major depressive disorder (MDD) is a severe mental illness characterized more by functional rather than structural brain abnormalities. The pattern of regional homogeneity (ReHo) deficits in MDD may relate to ...
Caring for Patients With Severe Anorexia Nervosa-A Capacity Evaluation Cannot Save Us [0.03%]
如何照顾患有严重神经性厌食症的患者--仅靠评估其自理能力是不够的
Emily G Holmes,Jane A Hartsock,Amy S Martin
Emily G Holmes
Prescription Stimulant Prescribing, Nonmedical Use, and Shortages: US FDA Research and Response [0.03%]
处方兴奋剂的开立、非医疗用途及短缺：美国FDA的研究与应对措施
Joshua P Rising,Robert M Califf
Joshua P Rising
Effective Components of Collaborative Care for Depression in Primary Care: An Individual Participant Data Meta-Analysis [0.03%]
初级保健中抑郁症合作护理的有效成分：个体参与者数据的荟萃分析
Hannah Schillok,Jochen Gensichen,Maria Panagioti et al.
Hannah Schillok et al.
Importance: Collaborative care is a multicomponent intervention for patients with chronic disease in primary care. Previous meta-analyses have proven the effectiveness of collaborative care for depression; however, indivi...
Suicide and Self-Harm Events With GLP-1 Receptor Agonists in Adults With Diabetes or Obesity: A Systematic Review and Meta-Analysis [0.03%]
GLP-1受体激动剂在糖尿病或肥胖成人中的自杀与自伤行为的系统评价和荟萃分析
Pouya Ebrahimi,Juan Carlos Batlle,Aryan Ayati et al.
Pouya Ebrahimi et al.
Importance: Bariatric surgery, once the criterion standard in obesity treatment, has a small but concerning association with increased suicidality. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs), originally develop...
Prescription Stimulant Use, Misuse, and Use Disorder Among US Adults Aged 18 to 64 Years [0.03%]
美国18至64岁成人中处方刺激药的使用、滥用及成瘾情况
Beth Han,Christopher M Jones,Nora D Volkow et al.
Beth Han et al.
Importance: Stimulants are increasingly prescribed for US adults. Whether such prescribing is associated with misuse and prescription stimulant use disorder (PSUD) is less understood. ...
Dost Öngür
Dost Öngür
Safety and Efficacy of Repeated Low-Dose LSD for ADHD Treatment in Adults: A Randomized Clinical Trial [0.03%]
成人ADHD治疗中重复小剂量LSD的安全性和有效性：一项随机临床试验
Lorenz Mueller,Joyce Santos de Jesus,Yasmin Schmid et al.
Lorenz Mueller et al.
Importance: Microdosing psychedelics, including lysergic acid diethylamide (LSD), has gained attention for its potential benefits in several psychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD)...
Maternal Inflammatory Proteins in Pregnancy and Neurodevelopmental Disorders at Age 10 Years [0.03%]
怀孕期间的母体炎症蛋白和孩子10岁时的神经发育障碍的关系
Tingting Wang,Parisa Mohammadzadeh,Jens Richardt Møllegaard Jepsen et al.
Tingting Wang et al.
Importance: Maternal inflammation during pregnancy has been associated with an increased risk of neurodevelopmental disorders (NDDs), such as attention-deficit/hyperactivity disorder (ADHD) and autism, and cognitive defic...