Mitchel R Stacy,Albert J Sinusas
Mitchel R Stacy
The field of regenerative medicine has experienced considerable growth in recent years as the translation of pre-clinical biomaterials and cell- and gene-based therapies begin to reach clinical application. Until recently, the ability to mo...
Ricardo Londono,Aaron X Sun,Rocky S Tuan et al.
Ricardo Londono et al.
Purpose of the review: This manuscript discusses wound healing as a component of epimorphic regeneration and the role of the immune system in this process. ...
Mechanisms of Pathology-Induced Neural Stem Cell Plasticity and Neural Regeneration in Adult Zebrafish Brain [0.03%]
成年斑马鱼脑病理诱导的神经干细胞可塑性和神经再生的机制研究
Caghan Kizil
Caghan Kizil
Purpose of the review: The purpose of this study is to review the current knowledge on the damage-induced molecular programs that underlie the regenerative ability in zebrafish brain. ...
Intrauterine Inflammation, Epigenetics, and Microbiome Influences on Preterm Infant Health [0.03%]
宫内炎症、表观遗传学和微生物组对早产婴儿健康的影响
Lei Lu,Erika C Claud
Lei Lu
Purpose of review: Significant research reveals that the microbiome modulates perinatal and postnatal health. This review aims to examine mechanisms by which intrauterine infection, the epigenome, and microbiome specifica...
Pluripotent Stem Cell-Derived Hepatocyte-like Cells: A Tool to Study Infectious Disease [0.03%]
人多能干细胞分化的肝类器官与细胞在感染性疾病研究中的应用
Robert E Schwartz,Yaron Bram,Angela Frankel
Robert E Schwartz
Purpose of review: Liver disease is an important clinical and global problem and is the 16th leading cause of death worldwide and responsible for 1 million deaths worldwide each year. Infectious disease is a major cause o...
Alerting the body to tissue injury: The role of alarmins and DAMPs in cutaneous wound healing [0.03%]
警觉机体组织损伤：皮肤伤口愈合中报警素和DAMPs的作用
Traci A Wilgus
Traci A Wilgus
Purpose of review: Tissue injury stimulates an inflammatory response that is mediated in part by alarmins. Alarmins are a group of endogenous molecules that trigger inflammation in response to damage. This class of molecu...
Targeting the Microbiota, from Irritable Bowel Syndrome to Mood Disorders: Focus on Probiotics and Prebiotics [0.03%]
从肠易激综合征到情绪障碍：聚焦益生菌和益生元治疗肠道微生物群
M M Pusceddu,K Murray,M G Gareau
M M Pusceddu
Purpose of review: The crosstalk between the gut and the brain has revealed a complex communication system responsible for maintaining a proper gastrointestinal homeostasis as well as affect emotional mood and cognitive f...
A New Paradigm for Tissue Diagnostics: Tools and Techniques to Standardize Tissue Collection, Transport, and Fixation [0.03%]
组织诊断的新范式：用于标准化组织采集、运输和固定的工具和技术
Daniel R Bauer,Michael Otter,David R Chafin
Daniel R Bauer
Purpose of review: Studying and developing preanalytical tools and technologies for the purpose of obtaining high-quality samples for histological assays is a growing field. Currently, there does not exist a standard prac...
Policing the intestinal epithelial barrier: Innate immune functions of intraepithelial lymphocytes [0.03%]
肠道上皮屏障的免疫 policing作用：上皮内淋巴细胞的固有免疫功能
Madeleine D Hu,Luo Jia,Karen L Edelblum
Madeleine D Hu
Purpose of review: This review will explore the contribution of IELs to mucosal innate immunity and highlight the similarities in IEL functional responses to bacteria, viruses and protozoan parasite invasion. ...
Tina L Morhardt,Atsushi Hayashi,John Y Kao et al.
Tina L Morhardt et al.
Purpose of review: The intestine contains the largest compartment of immune regulatory cells which include T regulatory cells and IL-10 producing macrophages. These cell populations serve to restrain unnecessary immune re...