Asmita Choudhury,Pranoti Mandrekar
Asmita Choudhury
Purpose of review: Alcohol associated liver disease (ALD) accounts for significant mortality and morbidity in the United States. Prolonged alcohol exposure leads to increased reactive oxygen species and oxidative stress r...
Advances in PET Diagnostics for Guiding Targeted Cancer Therapy and Studying In Vivo Cancer Biology [0.03%]
正电子发射断层扫描技术在指导癌症靶向治疗和活体癌症生物学研究中的新进展
David A Mankoff,Austin R Pantel,Varsha Viswanath et al.
David A Mankoff et al.
Purpose of the review: We present an overview of recent advances in positron emission tomography (PET) diagnostics as applied to the study of cancer, specifically as a tool to study in vivo cancer biology and to direct ta...
Michael A Kochen,Steven S Andrews,H Steven Wiley et al.
Michael A Kochen et al.
Purpose of review: Signaling pathways serve to communicate information about extracellular conditions into the cell, to both the nucleus and cytoplasmic processes to control cell responses. Genetic mutations in signaling ...
Peter N Mittwede,Riccardo Gottardi,Peter G Alexander et al.
Peter N Mittwede et al.
Purpose of review: Orthopaedic trauma is a major cause of morbidity and mortality worldwide. Although many fractures tend to heal if treated appropriately either by nonoperative or operative methods, delayed or failed hea...
Chemokine-Based Therapeutics for the Treatment of Inflammatory and Fibrotic Convergent Pathways in COVID-19 [0.03%]
基于趋化因子的治疗技术用于COVID-19炎症和纤维化 convergent pathways 的治疗
Dana R Julian,Megan A Kazakoff,Akhil Patel et al.
Dana R Julian et al.
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the SARS-CoV-2 betacoronavirus and has taken over 761,426 American lives as of the date of publication and will likely result in long-term, if not permanent, tissue dama...
The Pathobiological Basis for Thrombotic Complications in COVID-19: a Review of the Literature [0.03%]
COVID-19患者血栓并发症的发病基础：文献综述
Lara Hoteit,Andrew-Paul Deeb,Elizabeth A Andraska et al.
Lara Hoteit et al.
Purpose of review: COVID-19 has rapidly evolved into a global pandemic infecting over two hundred and forty-four million individuals to date. In addition to the respiratory sequelae and systemic infection that ensues, an ...
Swati Sharma,Roza Parveen,Biswa Prasun Chatterji
Swati Sharma
Nanoparticles have revolutionized biomedicine especially in the field of drug delivery due to their intriguing properties such as systemic stability, level of solubility, and target site specificity. It can, however, be both beneficial and ...
Acceleration of PDE-Based Biological Simulation Through the Development of Neural Network Metamodels [0.03%]
基于偏微分方程的生物模拟通过神经网络代理模型加速
Lukasz Burzawa,Linlin Li,Xu Wang et al.
Lukasz Burzawa et al.
Purpose of review: Partial differential equation (PDE) mathematical models of biological systems and the simulation approaches used to solve them are widely used to test hypotheses and infer regulatory interactions based ...
Jonathan M Eby,Farah Sharieh,John J Callaci
Jonathan M Eby
Purpose of review: Alcohol use continues to rise globally. We review the current literature on the effect of alcohol on bone health, homeostasis and fracture repair to highlight what has been learned in people and animal ...
Russell S Dulman,Gabriela M Wandling,Subhash C Pandey
Russell S Dulman
Purpose of review: Chronic alcohol use is a worldwide problem with multifaceted consequences including multiplying medical costs and sequelae, societal effects like drunk driving and assault, and lost economic productivit...