Synergies revealed: RNA-seq study of C. acetobutylicum and C. carboxidivorans co-cultured in the presence of conductive materials [0.03%]
协同作用的揭示：导电材料存在时C.acetobutylicum和C.carboxidivorans共培养的RNA测序研究
L Feliu-Paradeda,Q Amorós-Espuña,E Perona-Vico et al.
L Feliu-Paradeda et al.
Co-cultures can improve substrate utilization and product yields, yet the dynamics between species remain highly variable and poorly understood. In this study, we investigated the metabolic and transcriptional interplay between Clostridium ...
Molecular epidemiological and genetic variability of Salmonella isolates from the tropical mountainous region of southern China (2017-2024) [0.03%]
2017-2024年中国南部热带山区沙门氏菌的分子流行病学和遗传变异性研究
Lebin Su,Haoyuan Lun,Nanyang Li et al.
Lebin Su et al.
Salmonella enterica is a leading foodborne pathogen worldwide, posing significant public health concerns. However, its prevalence in mountainous regions in China remains unclear. This study analyzed 384 Salmonella strains isolated from 2,54...
Antimicrobial efficacy of Bifidobacterium longum FB1-4 cell-free supernatant against MRSA: insights into mechanisms and food matrix application [0.03%]
长双歧杆菌FB1-4胞外上清的抗MRSA功效：机制和食品基质应用的新见解
Jing Wang,Qisijing Liu,Yarui Liu et al.
Jing Wang et al.
The food safety landscape faces a significant challenge from methicillin-resistant Staphylococcus aureus (MRSA), a virulent and antibiotic-resistant foodborne pathogen. This study investigates the antimicrobial properties and mechanisms of ...
Alterations in the gut virome of children with allergic rhinitis: enrichment of pro-inflammatory bacteriophages and depletion of fungal viruses [0.03%]
儿童过敏性鼻炎患者的肠道病毒组变化：致炎细菌噬菌体富集和真菌病毒耗竭
Wei Yang,Lindong Shi,Xiuyun Li et al.
Wei Yang et al.
This study aimed to characterize the gut virome in children with allergic rhinitis (AR) and explore its interactions with immune markers and allergens. Metagenomic sequencing was performed on fecal samples from 16 AR and 17 healthy control ...
African swine fever virus genes vectored by simian adenoviruses do not protect against virulent genotype II virus challenge [0.03%]
单纯疱疹病毒基因不能保护非致死性II型猪瘟病毒感染
Priscilla Y L Tng,Laila Al-Adwani,Lynnette C Goatley et al.
Priscilla Y L Tng et al.
African swine fever virus (ASFV) causes a lethal hemorrhagic disease in domestic pigs, wild boar, and other members of the genus Sus. Since the introduction of the virus into Georgia in 2007, the disease has spread across Eurasia causing th...
Comparison of two IGRA assays exploring cell-mediated immunity against CMV, BKV, and EBV in kidney transplant patients [0.03%]
比较两种IGRA检测方法评估肾移植患者细胞介导免疫反应对抗CMV、BKV和EBV的效果
Aurélie Truffot,Soizic Daniel,Lucie Fusillier et al.
Aurélie Truffot et al.
Monitoring cellular immune responses (CMIs) appears to be a new biomarker in managing immunocompromised patients, especially kidney transplant recipients. This study compared the performance of two interferon-gamma (IFN-γ)-based assays-enz...
Insights into antibiotic resistomes from gut metagenome-assembled genomes of the free-range pigs [0.03%]
家猪肠道宏基因组揭示的抗生素抗性基因分布特征
Xihui Dai,Huan Liu,Xue Bai et al.
Xihui Dai et al.
The pig gut microbiome serves as a reservoir for antibiotic resistance genes (ARGs), which pose a threat to public health and environmental safety. To investigate the presence of ARGs carried by free-range pigs, which have frequent contact ...
Samantha M Felton,Joseph M Ficarrotta,Glynis L Kolling et al.
Samantha M Felton et al.
RNA isolation is a critical first step for gene expression analysis; however, obtaining high-quality RNA from polysaccharide-rich or biofilm-producing microbial samples remains challenging. High polysaccharide content hinders cell lysis, de...
Antifungal potential of naphthoquinone derivatives: screening of shikonin-based compounds and mechanistic insights into 5,8-dihydroxy-1,4-naphthoquinone against Candida albicans in vitro and in vivo [0.03%]
以石碳酸为基础的萘醌类衍生物抗真菌潜能筛选及体内外抗白色念珠菌的作用机制研究
Qingqing Chen,Minkai Yang,Xiaohui Lai et al.
Qingqing Chen et al.
Invasive fungal infections (IFIs), predominantly caused by Candida albicans, are a significant threat to immunocompromised individuals. The emergence of drug-resistant strains has intensified the need for novel antifungal agents. Natural na...
Integrative analysis of Poly(A)-seq and RNA-seq reveals transcriptional regulation of poly(A) tail length in tuberculosis [0.03%]
整合分析Poly(A)-seq和RNA-seq数据揭示了结核分枝杆菌mRNA多聚腺苷酸尾巴长度的转录后调控机制
Bahetibieke Tuohetaerbaike,Jie Wang,Ying Li et al.
Bahetibieke Tuohetaerbaike et al.
Tuberculosis (TB) is a serious global health problem, and the molecular mechanisms underlying TB pathogenesis remain poorly understood to date. Differential expression of many genes is an important contributor to TB, and poly(A) tails have ...