Adjuvant Lactiplantibacillus plantarum Lp05 modulates gut microbiota and alleviates symptoms during Helicobacter pylori eradication [0.03%]
辅助乳植氏植物杆菌Lp05调节胃肠道微生物群并缓解根除幽门螺旋杆菌期间的症状
Yuru Fu,Jie Dong,Leyi Xu et al.
Yuru Fu et al.
Helicobacter pylori eradication therapy is often accompanied by gastrointestinal adverse effects and gut microbiota dysbiosis. The role of specific probiotic strains in mitigating these issues requires further clinical evidence. In a random...
Clinical characteristics, risk factors, and pathogen spectrum of mixed infections in children with Mycoplasma pneumoniae pneumonia: a retrospective cohort study of 1,428 cases from a children's medical centre in East China [0.03%]
中国东部儿童肺炎支原体肺炎合并感染的临床特征、危险因素及病原谱系：一项1428例回顾性队列研究
Cheng Wang,Shenghao Hua,Yang Li et al.
Cheng Wang et al.
This study aimed to investigate the clinical characteristics, risk factors, and pathogen spectrum of mixed infections in children with Mycoplasma pneumoniae pneumonia (MPP). A total of 1,428 pediatric MPP patients were retrospectively inclu...
WormSpot: a machine learning-powered viability scoring platform in C. elegans for Candida pathogenicity studies [0.03%]
WormSpot：一种基于机器学习的秀丽隐杆线虫存活评分平台，用于念珠菌致病性研究
Jonathan Guo Wei Lee,Victor Eng Yong Ong,Dan Zhang
Jonathan Guo Wei Lee
Invasive Candida infections pose a critical health challenge, exacerbated by emerging antifungal resistance. Caenorhabditis elegans (C. elegans) offers a genetically tractable and scalable model for studying Candida pathogenicity, yet conve...
Han Yan,Qianying Jia,Jing Liu et al.
Han Yan et al.
Functional constipation (FC) is a common gastrointestinal disorder that can seriously affect patients' quality of life. Probiotics have emerged as a promising strategy for preventing and managing gastrointestinal diseases. Previously, we is...
Quantification of the coupled dynamics of marine microbes and reactive oxygen species in laboratory batch culture experiments [0.03%]
基于实验室批量培养实验的微生物与活性氧类物质的耦合动力学量化研究
Donna K McCullough,Emily C Bowden,Benjamin C Calfee et al.
Donna K McCullough et al.
Prochlorococcus, the smallest and most numerous phytoplankter of the oligotrophic surface ocean, is vulnerable to damage by the reactive oxygen species hydrogen peroxide (H2O2). The most harmful effects of exogenous H2O2 are mitigated by de...
Microbiota variation in Aedes aegypti (Diptera:Culicidae): a comparative study of field-caught and laboratory-adapted reared populations [0.03%]
埃及伊蚊(Aedes aegypti)微生物群系变异：野外捕捉与实验室培养种群的比较研究
Abelgie Sánchez-Amézquita,David Martínez,Omar Cantillo-Barraza et al.
Abelgie Sánchez-Amézquita et al.
The control of Aedes aegypti, the main vector of Dengue, Zika, and Chikungunya, remains a global health priority due to its expanding distribution and the absence of specific treatments. The mosquito's microbiota is increasingly recognized ...
Evaluation of the high-throughput RespiV PlexPlus multiplex assay compared to BioFire Respiratory Panel 2.1 plus [0.03%]
高通量RespiV PlexPlus多重检测与BioFire呼吸道病原体2.1 Plus检测对比评估研究
Todd M Pryce,Erin J Haygarth,Angelica S Lacsina et al.
Todd M Pryce et al.
During the 2023 Australian winter respiratory virus season, 2,000 clinical samples were prospectively tested over 47 days (July-August 2023) using the BioFire Respiratory Panel 2.1 plus (RP2.1+) assay, which detects 19 viral and 4 bacterial...
The deletion of a major facilitator superfamily gene VdMFS2 results in enhanced pathogenicity of Verticillium dahliae to cotton [0.03%]
鬼笔环肽31通过宿主免疫抑制促进镰刀菌根病发病性
Tiange Sun,Yongtai Li,Yuanjing Li et al.
Tiange Sun et al.
Among soil-borne phytopathogenic fungi, Verticillium dahliae is recognized as a devastating causal agent of cotton Verticillium wilt. Elucidation of molecular interactions between V. dahliae and cotton plants remains critical for disease co...
CRISPR-Cas9-mediated targeted gene deletion in Aspergillus calidoustus, a non-model environmental mold [0.03%]
高效编辑非经典产黄镰刀菌基因组的新系统
Jeffrey M Hollomon,Kurt M Dahlstrom
Jeffrey M Hollomon
Reverse genetic approaches in molds are complicated by their recalcitrance to transformation, multicellular growth during much of the vegetative life cycle, and frequent off-target integration of deletion constructs. Thus, protocols for gen...
Seasonal variations drive microbial community structure and nitrogen cycling in sediments of tributary pumping station forebays [0.03%]
季节变化驱动支流泵站前池沉积物微生物群落结构和氮循环
Xiaofu Wei,Weiwei Song,Siyuan Li
Xiaofu Wei
Discharge from tributary pumping stations often impacts mainstream water quality, yet microbial communities and nitrogen metabolism in pumping station forebays remain poorly understood. Therefore, this study investigated the microbial commu...