Serlogical, virulence, and molecular characterization of clinical and seafood Vibrio parahaemolyticus isolates [0.03%]
临床和海鲜来源的创伤弧菌分离株的血清学、毒力及分子表征
Yan Zhang,Xiaoyun Zhang,Shuo Yuan et al.
Yan Zhang et al.
In this study, 42 clinical and 114 seafood isolates of V. parahaemolyticus from Shanghai, China, were investigated. Serotypes, Kanagawa phenomenon (KP), potential virulence factors, and phylogenetic relationship (gyrB gene) of these isolate...
Synergistic effects of crop straw formulations on Stropharia rugosoannulata cultivation and soil microecology in continuous cropping systems [0.03%]
作物秸秆配方对连作系统中沟纹丛梗红菌栽培及土壤微生态的协同效应研究
Mengjiao Ding,Nianjie Shang,Lukuo Zhou et al.
Mengjiao Ding et al.
Biological amendment strategies effectively enhance the physical and chemical properties of continuously cropped soils, offering an environmentally sustainable and economically viable solution. This study investigated the impacts of distinc...
Integrated gut microbiota and metabolome signatures revealed by deep metagenomic sequencing in post-stroke cognitive impairment with type 2 diabetes [0.03%]
基于深度元基因组测序的脑卒中后认知障碍合并糖尿病肠道菌群及代谢组图谱研究
Xiaoye Liu,Lai-Yu Kwok,Wenyi Zhang
Xiaoye Liu
Post-stroke cognitive impairment (PSCI) is significantly exacerbated in individuals with type 2 diabetes mellitus (T2DM), yet the underlying gut microbial and metabolic mechanisms remain unclear. In this study, baseline fecal samples from 2...
tRNA-derived small RNA, tsRNA-5017b, as a novel biomarker for predicting severity in severe fever with thrombocytopenia syndrome [0.03%]
由塞来世炎伴血小板减少综合征病情严重程度预测的新生物标志物tsRNA-5017b的发现及功能研究
Wanying Zhang,Jiawei Feng,Shixing Chen et al.
Wanying Zhang et al.
tRNA-derived small RNAs (tsRNAs) represent a novel class of highly conserved non-coding RNAs that play crucial roles in various cellular processes, including cell proliferation and the initiation of viral reverse transcription. Despite thei...
Hospital-wide pathogen transmission surveillance combining epidemiological, genetic, and spectroscopic approaches [0.03%]
结合流行病学、基因组和光谱方法的全院病原体传播监测体系
Sophia Wolf,Elisabeth Barth-Jakschic,Baris Bader et al.
Sophia Wolf et al.
Nosocomial infections, particularly those caused by multidrug-resistant organisms, pose a significant challenge in healthcare facilities. This study presents a novel approach that combines tracking patient contacts in the hospital with Four...
Multi-omics analysis identifies a role for Streptococcus suis MnmE in growth regulation and environmental adaptation [0.03%]
多组学分析揭示了S.suis MnmE在生长调节和环境适应中的作用
Yuxuan Huang,Jing Sun,Jiyu Zhao et al.
Yuxuan Huang et al.
Streptococcus suis is a major bacterial pathogen of pigs and a significant zoonotic threat to human health. A critical unresolved question is whether the bacterium can rapidly respond to adverse environmental conditions by regulating the ex...
Genomic epidemiology and molecular characterization of Streptococcus pyogenes isolates from pediatric infections in Beijing, China [0.03%]
北京儿童链球菌感染的基因组流行病学及分子特征分析
Zexuan Song,Lin Zhou,Wenjian Xu et al.
Zexuan Song et al.
Streptococcus pyogenes (Group A Streptococcus, GAS) remains a formidable global public health challenge. In this study, we conducted a high-resolution genomic epidemiology study on 176 non-invasive throat GAS isolates collected from pediatr...
Dairy manure reception pits as reservoirs of extracellular DNA-associated antibiotic resistance genes [0.03%]
牛粪接收坑中与细胞外DNA相关的抗性基因抗生素储备功能研究
Najmuj Sakib,Daniel Andersen,Laura Jarboe et al.
Najmuj Sakib et al.
Dairy manure reception pits receive fresh manure and milkhouse wash water, and have short residence times, yet their role as reservoirs of extracellular antibiotic resistance genes (exARGs) remains poorly characterized. Here, we quantified ...
Schiff base-assisted catalytic fabrication of TiO2 nanoparticles for antibacterial applications against multidrug-resistant strains [0.03%]
席夫碱辅助制备用于对抗多重耐药菌株的二氧化钛纳米颗粒抗菌应用研究
Farasat Bibi,Ahtaram Bibi,Naila Khalid et al.
Farasat Bibi et al.
The emergence of multidrug-resistant (MDR) bacteria poses a significant global health challenge, necessitating the development of novel antimicrobial agents. In this study, titanium dioxide (TiO2) nanoparticles were synthesized via a sol-ge...
Chlamydia trachomatis inhibits NF-κB-dependent ferroptosis through PARP10 upregulation to promote reproduction [0.03%]
沙眼衣原体通过PARP10上调抑制NF-κB依赖性铁死亡以促进自身繁殖
Xinglv Wang,Yewei Yang,Hongrong Wu et al.
Xinglv Wang et al.
Chlamydia trachomatis (Ct), an obligate intracellular pathogen, manipulates host cell death pathways to establish infection. Although ferroptosis-an iron-dependent cell death process marked by lipid peroxidation-constitutes an antimicrobial...