Genomic and functional characterization of a blaNDM-1 and tmexCD2-toprJ2 co-producing Klebsiella quasipneumoniae (KL159/ST1929) reveals plasmid-mediated suppression of virulence [0.03%]
Feng Nie,Tianyu Zou,Ruihang Luo et al.
Feng Nie et al.
Klebsiella quasipneumoniae has emerged as a multidrug-resistant (MDR) pathogen of growing clinical concern, driven by its capacity to acquire mobile genetic elements encoding carbapenemases and novel resistance determinants. This study aime...
Mo Li,Qianyu Zhang,Tong Wu et al.
Mo Li et al.
Association of nasopharyngeal Dolosigranulum pigrum and Corynebacterium species with post-acute sequelae of SARS-CoV-2 in a longitudinal cohort [0.03%]
Bradley Ward,Laure B Bindels,Jean-Luc Balligand et al.
Bradley Ward et al.
This longitudinal study investigated the differential composition of the nasopharyngeal microbiome in patients presenting different COVID-19 infectious phenotypes and its evolution during convalescence, with a focus on post-acute sequelae o...
Comparison of two sentinel species Gammarus fossarum and Dreissena polymorpha for monitoring fecal viral contamination of continental waters [0.03%]
Marjorie Lortholarie,Julie Do Nascimento,Alain Geffard et al.
Marjorie Lortholarie et al.
Biomonitoring is a widely used strategy for evaluating chemical contamination. Two species are used in particular in French rivers: Dreissena polymorpha and Gammarus fossarum. Although biomonitoring of fecal contamination has been initiated...
Dairy manure, glyphosate, and antimicrobials (copper, streptomycin, and triazole) modulated the composition of antimicrobial resistance at the gene and microbial levels in a processing tomato field [0.03%]
Loic Deblais,Gabrielle Derippe,Madeline Horvat et al.
Loic Deblais et al.
Intensive pesticide use drives antimicrobial resistance (AMR) in agriculture, yet the effects of specific practices remain poorly understood. This study evaluated the impact of dairy manure and agrochemicals (glyphosate, copper, streptomyci...
Targeting MCR-3 and membrane biosynthesis: mechanistic insights into pterostilbene-colistin synergy [0.03%]
Fei Zeng,Wenjuan Yin,Huilian Duan et al.
Fei Zeng et al.
Colistin is a crucial antibiotic for treating infections caused by multidrug-resistant Enterobacterales. However, the emergence of plasmid-mediated mcr genes has significantly compromised their clinical efficacy. Natural adjuvants, such as ...
Evaluation of serine protein kinase HPrK as an antibacterial target in gram-positive bacteria and mycoplasmas [0.03%]
Hengfei Yan,Jiajia Xu,Tingting Jiang et al.
Hengfei Yan et al.
Antimicrobial resistance (AMR) poses a serious threat to global public health. To tackle this challenge, identifying novel effective antibacterial targets and antibiotics is crucial. The serine kinase HPrK, widely present in gram-positive b...
Evaluation of multiple extraction and inactivation methods for the rapid identification of filamentous fungi using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry [0.03%]
Halimat Olaniyan,Chris Kendra,Alexandria Dugan et al.
Halimat Olaniyan et al.
Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) offers high sensitivity for the rapid identification of microbial isolates. While predominantly used in bacterial and yeast identification within th...
Potential dissemination of IncHI2/IncHI2A plasmids carrying mcr-9.4 complex transposon in chicken-derived Enterobacter hormaechei [0.03%]
Panpan Liu,Mengke Ru,Baocheng Hao et al.
Panpan Liu et al.
The escalating global prevalence of antimicrobial resistance(AMR) represents a critical public health challenge, particularly concerning the compromised efficacy of polymyxins-essential therapeutic agents against carbapenem-resistant Gram-n...
Macrolide resistance determinants and their associations in streptococci from selected livestock and wildlife species from Catalonia, Northeast Spain [0.03%]
Guillem López de Egea,Aida González-Díaz,Virginia Aragón et al.
Guillem López de Egea et al.
The increasing macrolide resistance in Streptococcus spp. causing human and animal infections in the last decades is a concern for global health. The objectives of this study were to analyze the macrolide resistance rates of Streptococcus s...