Protection of mice against septic shock induced by lethal intraperitoneal dose of LPS by a recombinant Fasciola hepatica fatty acid binding protein [0.03%]
利用基因工程肝片吸虫脂肪酸结合蛋白保护小鼠内毒素败血症模型的存活率
Albersy Armina-Rodriguez,Stephanie M Dorta-Estremera,Loyda B Mendez et al.
Albersy Armina-Rodriguez et al.
Sepsis caused by Gram-negative bacteria is a severe systemic infection characterized by an excessive inflammatory response triggered by lipopolysaccharide (LPS), a potent endotoxin of these bacteria, often leading to organ failure and high ...
Targeted next-generation sequencing for comprehensive diagnosis and drug resistance detection in pulmonary and extrapulmonary tuberculosis: a single-center retrospective study [0.03%]
针对肺和肺外结核的全面诊断及耐药检测的目标二代测序技术的单中心回顾性研究
Jingyi Dai,Qiujing Li,Juan Wan et al.
Jingyi Dai et al.
Tuberculosis (TB), including drug-resistant forms, is a significant global health issue requiring accurate and rapid diagnostic tools. Traditional diagnostic methods suffer from low sensitivity and slow results, while nucleic acid amplifica...
Md Adnan Karim,Dennis LaJeunesse
Md Adnan Karim
Mechanical forces shape biological functions at all levels of life: biomolecules, cells, tissues, and organs. Shear flow, i.e., the transfer of momentum from regions of high momentum to those of lower momentum, influences the formation of m...
Association of vaginal microbiome, cytokines, and spontaneous preterm birth among Chinese women: a nested case-control study [0.03%]
中国妇女阴道菌群、细胞因子和自发性早产的相关性：一项病例对照研究
Yefang Ke,Ying Sun,Jun Wu et al.
Yefang Ke et al.
An imbalance of the vaginal microbiome and dysregulation of cytokines are associated with spontaneous preterm birth (sPTB). To date, the relationship between the vaginal microbiome, cytokines, and sPTB remains unclear in the Chinese populat...
Evolutionary dynamics of endogenous densoviruses NS1 proteins reveal ancient codivergence with their Platyhelminth hosts [0.03%]
端源病毒NS1蛋白的进化动力学揭示了与扁形虫宿主远古共演化的历史
Han Zhang,Juan Xu,Xiaodong Su et al.
Han Zhang et al.
Endogenous viral elements serve as molecular fossils of ancient viral infections, providing valuable evidence for reconstructing the evolutionary history of modern viruses and their hosts. These genomic remnants also provide crucial benchma...
Effects of Saccharomyces cerevisiae on the regulation of skatole, microorganisms, and tryptophan metabolites in vitro fermentation of pig [0.03%]
酿酒酵母对体外发酵调控猪粪斯可替、微生物及色氨酸代谢物的影响
Xiaoli Gao,Shengwei Zhang,Shanshan Ge et al.
Xiaoli Gao et al.
Skatole (3-methylindole), one of the most malodorous compounds from swine manure, poses serious risks to animal, human, and environmental health. Therefore, it has become a serious concern in livestock farming. Saccharomyces cerevisiae is w...
Divergent roles of hcp genes in Salmonella typhimurium T6SS shape gut microbiota dysbiosis during infection [0.03%]
Salmonella Typhimurium菌毛蛋白在调控T6SS毒力中的不同作用及其对感染小鼠肠道微生态的影响
Jia Liu,Jiao Liu,Chengjie Feng et al.
Jia Liu et al.
Salmonella enterica subsp. enterica serovar typhimurium (S. typhimurium) is a facultative intracellular pathogen causing significant gastrointestinal infections in both humans and animals. The type VI secretion system (T6SS) plays a crucial...
Different combinations of lignocellulolytic enzymes and lactic acid bacteria affect the quality and aerobic stability of rain-soaked Sudan grass silage by regulating the silage microbial community [0.03%]
纤维素降解酶和乳酸菌的不同组合通过调节青贮微生物群落影响降雨象草青贮品质和好氧稳定性的试验研究
Mengxin Li,Qiang Yu,Ya Su et al.
Mengxin Li et al.
This study evaluated the effects of ferulic acid esterase (FAE)-producing Lactiplantibacillus plantarum (LP; 1 × 10⁶ cfu·g⁻¹ FM), applied alone or with cellulase and xylanase (LCX; each enzyme 25 U·g⁻¹ FM) or cellulase and laccase (...
A mutation-aware proteomics approach for designing a multi-epitope vaccine against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa [0.03%]
一种针对多重耐药鲍曼不动杆菌和绿脓杆菌的多表位疫苗设计的蛋白质组学方法：关注突变意识
Gul Afshan,Namrah Yaseen,Asad U Khan
Gul Afshan
The increasing prevalence of multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa in healthcare settings presents a critical challenge to global public health, necessitating the development of effective therapeutic strateg...
The regional landscape of the human colon culturome in health and cystic fibrosis [0.03%]
健康状态和囊性纤维化状态下人类结肠培养生物圈的地域分布特征分析
Sarvesh V Surve,Rebecca A Valls,Kaitlyn E Barrack et al.
Sarvesh V Surve et al.
Cystic fibrosis (CF) alters gut physiology, yet its impact on microbial communities across colonic regions (ascending, transverse, descending colon) and microhabitats (lumen, mucosa) remains incompletely understood. Here, we applied culturo...