Regulation of Ras signal transduction during T cell development and activation [0.03%]
T细胞发育和活化过程中Ras信号转导的调控
Philip E Lapinski,Philip D King
Philip E Lapinski
T cell receptor-induced activation of the Ras signaling pathway is essential for T cell development, proliferation and differentiation. Given the central role of Ras in T cell biology its activation must be tightly regulated. However, preci...
TLR9 is dispensable for intestinal ischemia/reperfusion-induced tissue damage [0.03%]
TLR9在肠缺血/再灌注所致组织损伤中无关紧要
Emily Archer Slone,Michael R Pope,Mary Roth et al.
Emily Archer Slone et al.
The mortality rate due to intestinal ischemia/reperfusion (IR) remains at 60-80%. As toll-like receptor (TLR) 4 has been shown to be critical for IR injury in several organs, including the intestine, and TLR9 is necessary for IR-induced dam...
Pregnancy amelioration of arthritis in SKG mice corresponds with alterations in serum amyloid A3 levels [0.03%]
妊娠改善SKG小鼠类风湿关节炎对应着血清淀粉样A3水平的变化
Laura A Shaw,Adrianne L Stefanski,Lisa K Peterson et al.
Laura A Shaw et al.
OBJECTIVES: Pregnancy leads to rheumatoid arthritis remission in humans. The objective of this study was to determine if the SKG mouse could serve as a model for pregnancy-associated inflammatory arthritis amelioration. In addition, the mat...