IL-21 expression during sublingual immunotherapy for allergic rhinitis [0.03%]
舌下免疫疗法治疗过敏性鼻炎过程中IL-21的表达
Chunrui Wang,Xiaowei Qin,Li Jiang et al.
Chunrui Wang et al.
Background: Allergic rhinitis (AR) is an inflammatory disorder involving immunoglobulin E (IgE)-mediated immune response. Interleukin (IL)-21 IL-21 can regulate immune cell functions and IgE production. We aimed to explor...
Retrospective analysis of von willebrand factor and microthrombus formation in septic shock: associations with TTP-like syndrome and sepsis-induced coagulopathy [0.03%]
Septic休克中von Willebrand因子和微血栓形成的研究：与TTP样综合征及脓毒症诱导的凝血障碍的关系
Yi Liu,Jinxi Yue,Qingqing Huang et al.
Yi Liu et al.
Objective: Sepsis shock is characterized by endothelial damage and coagulation abnormalities. However, the relationship between von Willebrand factor (vWF), microthrombosis, and various clinical phenotypes such as thrombo...
Preventing sino-nasal polyposis recurrence after functional endoscopic sinus surgery: a multicentric study [0.03%]
内窥镜鼻窦手术后鼻窦乳突炎复发的预防：一项多中心研究
Goran L Omer
Goran L Omer
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently recurs after functional endoscopic sinus surgery (FESS), particularly in patients with eosinophilic inflammation or aspirin-exacerbated respiratory ...
Immune-metabolic crosstalk in rheumatoid arthritis: mediation effects of plasma metabolites on inflammatory cytokines [0.03%]
免疫代谢在类风湿关节炎中的相互作用：血浆代射产物介导炎症细胞因子的作用
Yuting Liang,Yanqiu Zhang,Jieyu Jin et al.
Yuting Liang et al.
Background: Rheumatoid arthritis (RA) is a chronic inflammatory condition defined by synovitis and progressive joint damage. The connection between inflammatory cytokines, molecules, and RA is still poorly understood desp...
Antagonists of platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) as rationale and therapeutic potential of combination cancer therapy [0.03%]
血小板源性生长因子及其受体的拮抗剂作为联合癌症治疗的理论依据和治疗潜力
Hai Qian,Ying Wang,Kwaku Appiah-Kubi
Hai Qian
Platelet-Derived Growth Factor (PDGF)/Platelet-Derived Growth Factor Receptor (PDGFR) are key regulators in the complex network of signaling from Receptor Tyrosine Kinases (RTKs). PDGFR has historically been considered an attractive therape...
Low-inflammatory macrophage-BMSC crosstalk enhances osteogenesis with attenuation of oxidative stress [0.03%]
低炎症巨噬细胞与骨髓间充质干细胞相互作用可减轻氧化应激并促进成骨分化
Tian Tian,Changhuan Liu,Lingnan Zhang et al.
Tian Tian et al.
Aim: Macrophage-mesenchymal stem cell (MSC) interactions critically influence bone regeneration during periodontitis resolution. While macrophage polarization under strong inflammatory conditions has been well studied, th...
Aerobic exercise versus acupuncture as adjuncts to acetylcholinesterase inhibitors in Alzheimer's disease: a systematic review and Bayesian network meta-analysis [0.03%]
阿尔茨海默病的治疗中有氧运动与针灸辅助胆碱酯酶抑制剂的疗效对比：系统评价和贝叶斯网络meta分析
Zhaoxie Yu,Hanzhang Li,Yao Wang et al.
Zhaoxie Yu et al.
Acetylcholinesterase inhibitors (AChEIs) remain the standard therapy for Alzheimer's disease (AD), yet their cognitive and functional benefits are limited, creating a strong need for effective adjunctive treatments. Aerobic exercise and acu...
Shared gene signatures between rheumatoid arthritis and Sjögren's syndrome [0.03%]
类风湿关节炎和舍格伦综合征共有的基因签名
Yi-Fan Li,Zhao-Wei Gao,Li Liu et al.
Yi-Fan Li et al.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to multiple complications. Sjögren's syndrome (SS) is another autoimmune condition that may occur as a primary disorder or in conjunction with other autoimmune disease...
The Escalating Global Burden of motor neuron disease: spatiotemporal trends among older adults, affected factors, and future projections [0.03%]
全球运动神经元疾病负担加剧：老年人的时空变化趋势、影响因素及未来预测
Yue-Yang Song,Shu-Ran Yao,Ling-Jun Li et al.
Yue-Yang Song et al.
Objective: Motor Neuron Disease (MND) is an increasing social health issue, in the cases of adults above 50 years of age, which requires the examination of its multidimensional burden, the spatiotemporal patterns, and the...
Xuexi Tang,Guoyan Li,Gang Wang et al.
Xuexi Tang et al.
Diabetic foot (DF), is called "foot gangrene" (gangrene) or "nerve gangrene" (gangrene of the nerve area) in traditional Chinese medicine. It is a severe complication of diabetes, whose incidence rate is high, and the consequences is seriou...