Reversal of oxidative stress-induced apoptosis in T and B lymphocytes by Coenzyme Q10 (CoQ10) [0.03%]
辅酶Q10（CoQ10）逆转T淋巴细胞和B淋巴细胞中的氧化应激诱导的细胞凋亡
Sastry Gollapudi,Sudhir Gupta
Sastry Gollapudi
Coenzyme Q10, (CoQ10) an electron transporter and an antioxidant, protects a variety of cell types against oxidative stress and apoptosis. However, protective effect of CoQ10 on oxidative stress-induced apoptosis in lymphocytes has not been...
Chloé Michaudel,Aurélie Couturier-Maillard,Pauline Chenuet et al.
Chloé Michaudel et al.
Exposure to ambient ozone causes airway hyperreactivity and lung inflammation, which represent an important health concern in humans. Recent clinical and experimental studies contributed to the understanding of the mechanisms of epithelial ...
Analysis of subsets of B cells, Breg, CD4Treg and CD8Treg cells in adult patients with primary selective IgM deficiency [0.03%]
原发性选择性IgM缺乏成人患者B细胞、Breg、CD4Treg和CD8Treg亚群分析
Ankmalika Gupta Louis,Sudhanshu Agrawal,Sudhir Gupta
Ankmalika Gupta Louis
Primary selective IgM deficiency (SIGMD) is a rare and recently IUIS-recognized primary immunodeficiency disease with increased susceptibility to infections, allergy, and autoimmune diseases. The pathogenesis of selective IgM remains unclea...
Li Yang,Liping Wang,Yi Zhang
Li Yang
Lung cancer is the most commonly diagnosed cancer as well as the leading cause of cancer-related deaths worldwide. To date, surgery is the first choice treatment, but most clinically diagnosed cases are inoperable. While chemotherapy and/or...
Syndrome of selective IgM deficiency with severe T cell deficiency associated with disseminated cutaneous mycobacterium avium intracellulaire infection [0.03%]
选择性IgM缺乏伴严重T细胞缺陷病合并广泛皮肤分枝杆菌感染综合征
Asal Gharib,Ankmalika Gupta Louis,Sudhanshu Agrawal et al.
Asal Gharib et al.
Cutaneous non-disseminated, non-tuberculous mycobacterial infections have been reported in both immunocompetent and immunocompromised subjects. Systemic Mycobacterium avium intracellulaire (MAI) have been reported in non-HIV patients with I...
Investigation of IL-21 gene polymorphisms (rs2221903, rs2055979) in cases with multiple sclerosis of Azerbaijan, Northwest Iran [0.03%]
调查阿塞拜疆西北部伊朗多发性硬化症患者中IL-21基因多态性（rs2221903，rs2055979）的情况
Tohid Gharibi,Tohid Kazemi,Mohammad Reza Aliparasti et al.
Tohid Gharibi et al.
Background: Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the Central Nervous System that is immunologically mediated in genetically susceptible individuals. IL-21, a cytokine produced by TCD4...
Glycyrrhizin down-regulates CCL2 and CXCL2 expression in cerulein-stimulated pancreatic acinar cells [0.03%]
甘草甜素下调内毒石胆酸刺激的胰腺外分泌细胞中CCL2和CXCL2的表达
Yaser Panahi,Shohreh Fakhari,Mehdi Mohammadi et al.
Yaser Panahi et al.
Many inflammatory chemokines release from leukocytes and pancreatic acinar cells which play important roles in pathophysiology of acute pancreatitis (AP). Of interests, CXCL2 and CCL2 have been shown elevated in the plasma of patients with ...
Association of IL-13 single nucleotide polymorphisms in Iranian patients to multiple sclerosis [0.03%]
IL-13单核苷酸多态性与伊朗多发性硬化症患者的关联研究
Narges Seyfizadeh,Tohid Kazemi,Mehdi Farhoudi et al.
Narges Seyfizadeh et al.
MS is an autoimmune disease and interleukin 13 (IL-13) has been proposed to be an important neuroprotective mediator in MS. Because of plausible effect of single nucleotide polymorphisms (SNPs) in expression level or biological activity of ...
Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications [0.03%]
泛素及泛素样修饰介导的T细胞受体复合物信号转导的调节机制研究进展
Samantha F Friend,Francina Deason-Towne,Lisa K Peterson et al.
Samantha F Friend et al.
Post-translational protein modifications are a dynamic method of regulating protein function in response to environmental signals. As with any cellular process, T cell receptor (TCR) complex-mediated signaling is highly regulated, since the...
G protein signaling modulator-3: a leukocyte regulator of inflammation in health and disease [0.03%]
健康与疾病中的炎性白细胞调节物G蛋白信号调节因子-3
Matthew J Billard,Bryan J Gall,Kristy L Richards et al.
Matthew J Billard et al.
G protein signaling modulator-3 (GPSM3), also known as G18 or AGS4, is a member of a family of proteins containing one or more copies of a small regulatory motif known as the GoLoco (or GPR) motif. GPSM3 interacts directly with Gα and Gβ ...