Estimating the age distribution of disease-causal HPV infection in women with high-grade cervical intraepithelial neoplasia in Denmark, Estonia, Norway, Slovenia, and Sweden: A modeling study [0.03%]
丹麦、爱沙尼亚、挪威、斯洛文尼亚和瑞典女性高级别宫颈上皮内瘤变中致病HPV感染的年龄分布估计：一项建模研究
Ugne Sabale,Alhaji Cherif,Stefano Valente et al.
Ugne Sabale et al.
The age distribution of disease-causal human papillomavirus (HPV) infections that lead to high-grade cervical intraepithelial neoplasia (CIN2+) is not well understood in Europe. The objective of this study was to estimate the age at acquisi...
Self-amplifying RNA (saRNA) and circular RNA (circRNA) vaccines: Progress, evidence gaps, and translational pathways for durable and scalable immunization [0.03%]
自我扩增型RNA（saRNA）和环形RNA（circRNA）疫苗：进展、证据缺口及持久性和可扩展性免疫的转化途径
Ugwu Okechukwu Paul-Chima,Okon Michael Ben,Ogenyi Fabian C et al.
Ugwu Okechukwu Paul-Chima et al.
Self-amplifying RNA (saRNA) and circular RNA (circRNA) are emerging vaccine modalities that extend conventional, non-replicating mRNA platforms. Self-amplifying RNA encodes a replicase that amplifies intracellular RNA templates, enabling hi...
Ivonescimab combined with chemotherapy for the treatment of metastatic cervical cancer: A case report and literature review [0.03%]
伊维莫司联合化疗治疗转移性宫颈癌的疗效观察及文献复习
Motong Xu,Shuo Qiu,Jie Zhou et al.
Motong Xu et al.
The prognosis for patients with recurrent or metastatic cervical cancer (r/mCC) remains challenging, with a 5-y survival rate of approximately 17%. Although first-line treatment has evolved from traditional single-agent chemotherapy to comb...
LILRB2 inhibition by blocking antibody ES009 reprograms immunosuppressive myeloid cells and enhances T-cell-mediated tumor immunity [0.03%]
LILRB2阻断型抗体ES009通过重组免疫抑制性髓系细胞增强T细胞介导的肿瘤免疫能力
Xiaofeng Niu,Chunnian Wang,Yanfen Hu et al.
Xiaofeng Niu et al.
The inhibitory receptor leukocyte immunoglobulin-like receptor B2 (LILRB2), expressed on myeloid cells like monocytes and tumor-resident myeloid cells, sustains an immunosuppressive tumor microenvironment and promotes tumor progression. Pha...
Oncolytic virus therapy for hepatocellular carcinoma: A bibliometric analysis of research landscapes, hotspots, and clinical transformation trends from 2000 to mid-2025 [0.03%]
溶瘤病毒治疗肝细胞癌的文献计量分析：2000年中期至2025年的研究格局、热点及临床转化趋势
Fei Yu,Sihan Yin,Jiayu Zhu et al.
Fei Yu et al.
This study aimed to systematically analyze the research status, hotspots, and trends of oncolytic virotherapy (OV) for hepatocellular carcinoma (HCC) from 2000 to mid-2025, scientifically predict future directions, facilitate clinical trans...
Childhood immunization barriers and interventions in low- and middle-income countries: A scoping review of access, delivery systems, and health literacy [0.03%]
发展中国家儿童免疫屏障及干预措施的研究：对低收入和中等收入国家的综述性研究——关于免疫途径、传递系统以及健康素养方面的问题
Yasmin Fatinah,Marsa Qolbina,Mohammed Alfaqeeh et al.
Yasmin Fatinah et al.
Childhood immunization is among the most effective public health measures for preventing infectious diseases and reducing child mortality, yet coverage in many low- and middle-income countries (LMICs) remains suboptimal due to barriers in a...
Irene Gobe,Thabiso Mogowa,Khutsafalo Kadimo et al.
Irene Gobe et al.
Mumps, though often self-limiting, can cause serious complications such as meningitis, orchitis, infertility, deafness, and seizures. Despite rising cases in Africa, most countries do not vaccinate against mumps. This review compiled availa...
Long-term immune protection after infant hepatitis B vaccination in children [0.03%]
婴儿接种乙肝疫苗的儿童长期免疫保护效果
Rodman Tarigan Girsang,Eddy Fadlyana,Muhammad Gilang Dwi Putra et al.
Rodman Tarigan Girsang et al.
Chronic hepatitis B virus (HBV) infection in endemic regions often begins in infancy and persists throughout life. Although anti-HBs antibody levels may decline over time, long-term protection usually remains. The me chanisms underlying thi...
Durable response of anaplastic thyroid cancer to pembrolizumab combined with chemotherapy: A case report [0.03%]
派姆单抗联合化疗治疗间变性甲状腺癌疗效持久的1例报告
Zipei Chen,Qiongshan Chen,Yihan Zhuang et al.
Zipei Chen et al.
Anaplastic thyroid cancer is a notoriously aggressive malignancy with a dismal prognosis, typically associated with a median overall survival of less than one year. Therapeutic alternatives are particularly limited for patients without acti...
Cost-effectiveness of pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma [0.03%]
帕博利珠单抗联合曲妥珠单抗和化疗治疗HER2阳性胃癌或食管胃交界处腺癌的成本效益分析
Kexin Yu,Qiaoping Xu
Kexin Yu
To investigate the cost-effectiveness of pembrolizumab in combination with trastuzumab and chemotherapy as a first-line treatment for HER2-positive gastric or gastro-esophageal junction adenocarcinoma from the perspective of the U.S. and Ch...