Osteopontin in cancer [0.03%]
骨桥蛋白与癌症的关系
Alpana Kumari,Dharambir Kashyap,Vivek Kumar Garg
Alpana Kumari
Osteopontin (OPN) is a heavily post-translationally modified protein with a molecular weight of 44-70 kDa, depending on the degree of glycosylation. OPN is involved in various biological processes, including bone remodeling, immune response...
Molecular biology of SARS-CoV-2 and techniques of diagnosis and surveillance [0.03%]
SARS-CoV-2的分子生物学及诊断和监测技术
Takayuki Ishige
Takayuki Ishige
The World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19), a disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a global pandemic in March 2020. Reverse transcription-polymerase chain ...
Jill Palmer,Kornelia Galior
Jill Palmer
Allowable total error (ATE) are performance specification limits predefined for a variety of laboratory analytes. These limits define the maximum amount of error that is allowed for an assay when judging acceptability of a new assay during ...
Thanat Chaikijurajai,Hernan Rincon-Choles,W H Wilson Tang
Thanat Chaikijurajai
Natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP), have been recommended as standard biomarkers for diagnosing heart failure (HF), and one of the strongest risk predictors for mortalit...
Jens F Rehfeld,Jens P Goetze
Jens F Rehfeld
This chapter attempts to provide an all-round picture of a dynamic and major branch of modern endocrinology, i.e. the gastrointestinal endocrinology. The advances during the last half century in our understanding of the dimensions and diver...
Palak Sondhi,Taiwo Adeniji,Dhanbir Lingden et al.
Palak Sondhi et al.
The outer membrane of gram-negative bacteria is primarily composed of lipopolysaccharide (LPS). In addition to protection, LPS defines the distinct serogroups used to identify bacteria specifically. Furthermore, LPS also act as highly poten...
Charlotte Delrue,Joris R Delanghe,Marijn M Speeckaert
Charlotte Delrue
Advanced glycation end products (AGEs), by-products of glucose metabolism, have been linked to the emergence of cardiovascular disorders (CVD). AGEs can cause tissue damage in four different ways: (1) by altering protein function, (2) by cr...
Advances in clinical chemistry patient-based real-time quality control (PBRTQC) [0.03%]
临床化学患者基于实时质控(PBRTQC)的进展
Mark A Cervinski,Andreas Bietenbeck,Alex Katayev et al.
Mark A Cervinski et al.
Patient-Based Real-Time Quality Control involves monitoring an assay using patient samples rather than external material. If the patient population does not change, then a shift in the long-term assay population results represents the intro...
Dustin Bunch,Amy L Pyle-Eilola
Dustin Bunch
Lead has been a known source of toxicity for millennia due to widespread use until the 20th century. Consequently, there remains significant, though decreasing, exposure to lead throughout the world. Clinical signs and symptoms of lead toxi...
Immunohematological testing and transfusion management of the prenatal patient [0.03%]
孕产妇的免疫血液学检验和输血管理
NurJehan Quraishy,Suneeti Sapatnekar
NurJehan Quraishy
The primary indication for immunohematological testing in the prenatal patient is to detect and identify maternal red cell antibodies. If there are antibodies that are expected to hemolyze the fetus' red cells, their strength of reactivity ...