Gregory S Makowski
Gregory S Makowski
Dieter Swandulla,Kay Ohlendieck
Dieter Swandulla
A dynamic extracellular matrix (ECM) surrounds individual cellular units and fills the intercellular space to provide physical support, structural organization and a medium for signaling mechanisms. This article focuses on the ECM in skelet...
Akhilesh Kumar Pathak
Akhilesh Kumar Pathak
Exhaled breath analysis is gaining significant attention among researchers due to its non-invasive potential in early diagnosis and disease monitoring. Volatile organic compounds (VOCs) present in exhaled breath can provide useful informati...
Aminopeptidase N (CD13): Bridging physiology, pathology and therapeutic potential [0.03%]
氨肽酶N(CD13):连接生理学、病理学和治疗潜力
Gabriel C Nwokolo,Robert A Falconer,Francis M Barnieh
Gabriel C Nwokolo
Aminopeptidase N (CD13) is a multifunctional protein recognized for its diverse roles as an enzyme, receptor, and signalling molecule, attributes that have earned it classification as a "moonlighting" protein. Its involvement in key biologi...
From nonexistence to novel applications: Nullomers and related k-mer based concepts in bioinformatics [0.03%]
从无中生有到开拓创新——生物信息学中的空序列及相关k-元组概念
Candace S Y Chan,Ilias Georgakopoulos-Soares
Candace S Y Chan
Underrepresented k-mer sequences, provide insights into evolutionary constraints, molecular mechanisms, and organismal fitness. Analysis of these sequences have broad applications across genomics and proteomics, such as in biomarker develop...
Sajjad Bakhtiari,Mohammad Rostami-Nejad
Sajjad Bakhtiari
Celiac disease (CD) is a chronic autoimmune disorder triggered by gluten ingestion in genetically predisposed individuals. Current diagnostic methods rely on serological markers, histological examination of duodenal biopsies, and HLA genoty...
Advances in optical biosensors: Technologies and trends in point of care applications [0.03%]
光学生物传感器进展：面向护理点应用的技术和趋势
Alper Baran Sözmen,Ayşe Ezgi Bayraktar,Özgür Ülker et al.
Alper Baran Sözmen et al.
A sensor detects changes in its environment and converts them into readable data using three key components: a receptor to sense changes, a transducer to generate a signal, and a detection system to output the signal. Optical sensors are de...
Gregory S Makowski
Gregory S Makowski
Tau and Amyloid beta causes microglial activation in Alzheimer's disease [0.03%]
tau和淀粉样β蛋白引发的阿尔茨海默病小胶质细胞活化现象
Subashchandrabose Chinnathambi,Anusree Adithyan,Madhura Chandrashekar et al.
Subashchandrabose Chinnathambi et al.
Alzheimer's disease is a neurodegenerative condition characterized by the accumulation of hyperphosphorylated Tau in neurofibrillary tangles and amyloid-beta plaques. Tau, a microtubule-associated protein essential for neuronal stability, d...
Tumor-associated carbohydrate antigens: Biomarker discovery and clinical application [0.03%]
肿瘤相关糖类抗原：生物标志物的发现及临床应用研究
Teresa Freire,Valeria da Costa
Teresa Freire
Tumor-Associated Carbohydrate Antigens (TACAs) are carbohydrate structures uniquely expressed on the surface of tumor cells while being absent or minimally present in normal tissues. These molecular signatures play crucial roles in tumor pr...