Advances in blood microsampling technology for cancer biomarker detection [0.03%]
癌症生物标志物检测的血液微量采样技术进展
Natasha Lucas,Ben R Herbert,Mark P Molloy
Natasha Lucas
Blood microsampling has demonstrated clinical utility for applications in the fields of newborn screening, therapeutic drug monitoring (TDM) of immunosuppressive drugs, and for viral detection. However, for cancer diagnostics, including ear...
Paul Dowling,Kay Ohlendieck
Paul Dowling
Proteomics using gel electrophoresis (GE) for efficient protein separation prior to mass spectrometry is a frequently employed and proteoform-centric analysis tool of biomedical chemistry. Isolated molecular species can be visualized by var...
The cancer microbiome [0.03%]
癌症微生物组学
Huapeng Li,Anne A Leaman,Qingfei Zheng
Huapeng Li
The cancer microbiome is an emerging concept that is referred to as the microorganism communities associated with cancer. There has been controversy in terms of the bona fide functions of the microbiome in carcinogenesis and cancer developm...
Gregory S Makowski
Gregory S Makowski
Hafiz Muhammad Arsalan,Hina Mumtaz,Antonio Simone Lagana
Hafiz Muhammad Arsalan
Endometriosis represents a diverse disease characterized by three distinct phenotypes: superficial peritoneal lesions, ovarian endometriomas, and deep infiltrating endometriosis. The most widely accepted pathophysiological hypothesis for en...
Arejas J Uzgiris,Lance A Ladic,Sophia X Pfister
Arejas J Uzgiris
This chapter provides a comprehensive summary of clinical laboratory testing for neurofilament light chain (NfL) in neurologic disease. A primer on the NfL structure and function is presented with its potential use as a biomarker. The most ...
Evangelos Kalogirou,Spyridon Voulgaris,George A Alexiou
Evangelos Kalogirou
Traumatic brain injury (TBI) represents a significant public health concern. Besides the initial primary injury, a defining point of TBI is causing secondary, delayed damage through inflammatory biochemical processes. Among the complication...
Mohammad Muzaffar Mir,Mushabab Alghamdi,Waad Fuad BinAfif et al.
Mohammad Muzaffar Mir et al.
Diabetes mellitus is a chronic condition caused by high blood glucose resulting from insufficient insulin production or cellular resistance to insulin action or both. It is one of the fastest-growing public health concerns worldwide. Develo...
Chrisanna Dobrowolski,Shu Min Lao,Fadi Kharouf et al.
Chrisanna Dobrowolski et al.
Renal involvement in systemic lupus erythematosus (SLE), lupus nephritis (LN), is common and can result in significant morbidity, including progressive renal dysfunction, and even ultimately leading to death. LN is heterogeneous complicated...
Subashchandrabose Chinnathambi,Nagaraj Rangappa,Madhura Chandrashekar
Subashchandrabose Chinnathambi
A key factor in the progression of Alzheimer's disease (AD) is internalization of extracellular Tau oligomers (ecTauOs) by neuroglial cells. Aberrant hyperphosphorylation of Tau results in their dissociation from microtubules and formation ...