Long non-coding and circular RNAs in osteoporosis: Translation to clinical practice [0.03%]
长链非编码和环状RNA在骨质疏松症中的研究及其临床应用展望
Martina Faraldi,Paola Maroni,Marta Gomarasca et al.
Martina Faraldi et al.
Non-coding RNAs (ncRNAs) belong to a class of untranslated nucleic acids involved in regulation of gene expression. ncRNAs are categorized as small (
Cardiac natriuretic peptides [0.03%]
心脏利钠多肽
Theodor W Shalmi,Anne Sophie B Jensen,Jens P Goetze
Theodor W Shalmi
Over the last four decades, cardiac natriuretic peptides have changed our understanding of patients with chronic heart failure. From the discovery of the heart as an endocrine organ with its own hormones and receptors, the biochemistry and ...
Shaukat A Khan,Fnu Nidhi,Andrés Felipe Leal et al.
Shaukat A Khan et al.
Glycosaminoglycans (GAGs) are sulfated polysaccharides comprising repeating disaccharides, uronic acid (or galactose) and hexosamines, including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate. Hyaluronan is an e...
Jaya Montecillo,Thomas Pirker,Christopher Pemberton et al.
Jaya Montecillo et al.
Soluble urokinase plasminogen activator receptor (suPAR), the soluble counterpart of urokinase plasminogen activator receptor, is found in the circulation at various levels. suPAR and its parent molecule, cell surface uPAR, exhibit similar ...
Mitochondria: A source of potential biomarkers for non-communicable diseases [0.03%]
线粒体：潜在生物标志物来源以用于非传染性疾病
Amulya Ichegiri,Kshitij Kodolikar,Vaibhavi Bagade et al.
Amulya Ichegiri et al.
Mitochondria, as an endosymbiont of eukaryotic cells, controls multiple cellular activities, including respiration, reactive oxygen species production, fatty acid synthesis, and death. Though the majority of functional mitochondrial protein...
Sumit Kinger,Yuvraj Anandrao Jagtap,Prashant Kumar et al.
Sumit Kinger et al.
Proteostasis is essential for normal function of proteins and vital for cellular health and survival. Proteostasis encompasses all stages in the "life" of a protein, that is, from translation to functional performance and, ultimately, to de...
Monika Dawid,Karolina Pich,Ewa Mlyczyńska et al.
Monika Dawid et al.
Reproductive success consists of a sequential events chronology, starting with the ovum fertilization, implantation of the embryo, placentation, and cellular processes like proliferation, apoptosis, angiogenesis, endocrinology, or metabolic...
Pleiotropic functions and clinical importance of circulating HDL-PON1 complex [0.03%]
循环HDL-PON1复合物的多效功能和临床意义
Abdolkarim Mahrooz
Abdolkarim Mahrooz
High density lipoprotein (HDL) functions are mostly mediated through a complex proteome, particularly its enzymes. HDL can provide a scaffold for the assembly of several proteins that affect each other's function. HDL particles, particularl...
Juan F Zapata-Acevedo,Alejandra Mantilla-Galindo,Karina Vargas-Sánchez et al.
Juan F Zapata-Acevedo et al.
The blood-brain barrier (BBB) is a dynamic interface that regulates the exchange of molecules and cells between the brain parenchyma and the peripheral blood. The BBB is mainly composed of endothelial cells, astrocytes and pericytes. The in...
Tear biomarkers [0.03%]
眼泪生物标志物
Erika Ponzini
Erika Ponzini
An extensive exploration of lacrimal fluid molecular biomarkers in understanding and diagnosing a spectrum of ocular and systemic diseases is presented. The chapter provides an overview of lacrimal fluid composition, elucidating the roles o...