Danielle M Luettel,Marcia R Terluk,Jaehyeok Roh et al.
Danielle M Luettel et al.
Gaucher disease (GD) is a rare lysosomal disorder characterized by the accumulation of glycosphingolipids in macrophages resulting from glucocerebrosidase (GCase) deficiency. The accumulation of toxic substrates, which causes the hallmark s...
Christina Mousele,David Holden,Sharmilee Gnanapavan
Christina Mousele
Neurofilaments (NFs), major cytoskeletal constituents of neurons, have emerged as universal biomarkers of neuronal injury. Neuroaxonal damage underlies permanent disability in various neurological conditions. It is crucial to accurately qua...
Anastasia Bougea
Anastasia Bougea
Digital biomarker (DB) assessments provide objective measures of daily life tasks and thus hold promise to improve diagnosis and monitoring of Parkinson's disease (PD) patients especially those with advanced stages. Data from DB studies can...
RNA biomarkers in cancer therapeutics: The promise of personalized oncology [0.03%]
癌症治疗中的RNA生物标志物：个性化医学的前景
Hector Katifelis,Maria Gazouli
Hector Katifelis
Cancer therapy is a rapidly evolving and constantly expanding field. Current approaches include surgery, conventional chemotherapy and novel biologic agents as in immunotherapy, that together compose a wide armamentarium. The plethora of ch...
Dalma Horvat,Lucia Agoston-Coldea
Dalma Horvat
The ever-increasing life expectancy of the global population introduces a critical perspective on the impact of aging as an immutable cardiovascular risk factor, particularly manifesting in the alterations observed in the pulmonary artery (...
Eglė Mazgelytė,Dovilė Karčiauskaitė
Eglė Mazgelytė
Cortisol, a stress hormone, plays a crucial role in regulating metabolic, hemodynamic, inflammatory, and behavioral processes. Its secretion is governed by the hypothalamic-pituitary-adrenal axis. However, prolonged activation of this axis ...
Yonca Senem Akdeniz,Seda Özkan
Yonca Senem Akdeniz
Chronic obstructive pulmonary disease (COPD), a global healthcare and socioeconomic burden, is a multifaceted respiratory disorder that results in substantial decline in health status and life quality. Acute exacerbations of the disease con...
Volatile organic compounds in cancer and exhaled breath detection technology [0.03%]
用于癌症检测的挥发性有机化合物及呼出气检测技术
Xinyuan Zhou,Manqing Qi,Mingqi Tang et al.
Xinyuan Zhou et al.
The detection of volatile organic compounds (VOCs) in breath has become a potential method for early cancer screening. Although this approach has attracted increasing attention from the both scientific and medical communities, it has not re...
Alyssa Sbisa,Kristin Graham,Ellie Lawrence-Wood et al.
Alyssa Sbisa et al.
Posttraumatic stress disorder (PTSD) is characterized by exposure to traumatic events and involves symptom domains such as intrusive thoughts, avoidant behaviors, negative mood, and cognitive dysfunction. The disorder can be chronic and deb...
Paolo Iadarola,Maura D&#x;Amato,Maria Antonietta Grignano et al.
Paolo Iadarola et al.
Lung diseases affect pulmonary and respiratory function and are caused by bacterial viral and fungal infection as well as environmental factors. Unfortunately, symptom overlap between various pulmonary diseases often prevents clear differen...