Tau and Amyloid beta causes microglial activation in Alzheimer's disease [0.03%]
tau和淀粉样β蛋白引发的阿尔茨海默病小胶质细胞活化现象
Subashchandrabose Chinnathambi,Anusree Adithyan,Madhura Chandrashekar et al.
Subashchandrabose Chinnathambi et al.
Alzheimer's disease is a neurodegenerative condition characterized by the accumulation of hyperphosphorylated Tau in neurofibrillary tangles and amyloid-beta plaques. Tau, a microtubule-associated protein essential for neuronal stability, d...
Tumor-associated carbohydrate antigens: Biomarker discovery and clinical application [0.03%]
肿瘤相关糖类抗原：生物标志物的发现及临床应用研究
Teresa Freire,Valeria da Costa
Teresa Freire
Tumor-Associated Carbohydrate Antigens (TACAs) are carbohydrate structures uniquely expressed on the surface of tumor cells while being absent or minimally present in normal tissues. These molecular signatures play crucial roles in tumor pr...
Md Abdur Rahman,Md Mahmodul Islam,Md Monirul Islam et al.
Md Abdur Rahman et al.
Metabolic syndrome is a group of cardio-metabolic dysfunctions characterized by increased fasting blood glucose, blood pressure, waist circumference, triglycerides, and decreased high-density lipoprotein cholesterol. Globally, the prevalenc...
Advances in malaria detection [0.03%]
疟疾检测新进展
Blessing Wisdom Ike,Vijayaraj Kathiresan,Lungelo Miya et al.
Blessing Wisdom Ike et al.
Malaria remains a significant global health issue, especially in tropical and subtropical regions. Although Egypt attained malaria-free status in 2024, countries like Eritrea, Ethiopia, Ghana, Kenya, Nigeria, Somalia, Sri Lanka, Sudan, and ...
Shagufta Kamal,Sumble Malik,Farwa Batool et al.
Shagufta Kamal et al.
Heavy metal toxicity poses significant risks to environmental and human health, necessitating advanced analytical and integrative approaches for assessment and mitigation. Herein we review the use of high-resolution metabolomics, ultra-high...
Cristina Mas-Bargues,Javier Huete-Acevedo,Marta Arnal-Forné et al.
Cristina Mas-Bargues et al.
Extracellular vesicles (EVs) are nanoscale particles released by cells into body fluids and serve as crucial mediators of intercellular communication. This chapter explores their biogenesis, cargo composition, and biological functions on ta...
Gregory S Makowski
Gregory S Makowski
Merve Asena Özbek,Özge Altıntaş,Fatma Yılmaz et al.
Merve Asena Özbek et al.
Biomimetic sensor technology, inspired by nature's ingenious designs, has garnered significant attention for its potential in revolutionizing various fields, ranging from healthcare to environmental monitoring. Recent advances in biomimetic...
Shereen M Aleidi,Abeer Malkawi,Hiba Al Fahmawi et al.
Shereen M Aleidi et al.
This chapter reviews the emerging role of metabolomics in nephrotic syndrome (NS), a kidney disorder characterized by proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Metabolomics provides valuable insights into the complex metaboli...
MDDB: A public databank of host microRNAs in Tuberculosis diagnosis [0.03%]
MDDB：结核病诊断用宿主miRNA的公共数据库
Piyush Agrawal,Aditya Upadhyay,Ravindra Kumar Chauhan et al.
Piyush Agrawal et al.
Tuberculosis (TB) remains a major global health challenge due to its high mortality rate. Several factors contribute significantly including delayed diagnosis, emergence of drug resistance, and biofilm formation. Although various diagnostic...