Endocrine disruption in metabolic disorders: Biomarkers and therapeutic targets [0.03%]
内分泌干扰物与代谢性疾病：生物标志物及治疗靶点
Hafiza Mamoona Ikram,Kanwal Rehman,Muhammad Sajid Hamid Akash et al.
Hafiza Mamoona Ikram et al.
Endocrine-disrupting chemicals (EDCs) are external agents that interfere with normal hormone production, release, movement, attachment, activity, and removal. EDCs operate through various mechanisms, including receptor binding, interference...
Rares Ilie Orzan,Andrada Seicean
Rares Ilie Orzan
Cholangiocarcinoma (CCA), a highly heterogeneous malignancy of the biliary tract, has emerged as a global health concern due to its rising incidence and poor prognosis. Its pathogenesis is shaped by complex interactions between environmenta...
Gregory S Makowski
Gregory S Makowski
Dieter Swandulla,Kay Ohlendieck
Dieter Swandulla
A dynamic extracellular matrix (ECM) surrounds individual cellular units and fills the intercellular space to provide physical support, structural organization and a medium for signaling mechanisms. This article focuses on the ECM in skelet...
Akhilesh Kumar Pathak
Akhilesh Kumar Pathak
Exhaled breath analysis is gaining significant attention among researchers due to its non-invasive potential in early diagnosis and disease monitoring. Volatile organic compounds (VOCs) present in exhaled breath can provide useful informati...
Aminopeptidase N (CD13): Bridging physiology, pathology and therapeutic potential [0.03%]
氨肽酶N(CD13):连接生理学、病理学和治疗潜力
Gabriel C Nwokolo,Robert A Falconer,Francis M Barnieh
Gabriel C Nwokolo
Aminopeptidase N (CD13) is a multifunctional protein recognized for its diverse roles as an enzyme, receptor, and signalling molecule, attributes that have earned it classification as a "moonlighting" protein. Its involvement in key biologi...
From nonexistence to novel applications: Nullomers and related k-mer based concepts in bioinformatics [0.03%]
从无中生有到开拓创新——生物信息学中的空序列及相关k-元组概念
Candace S Y Chan,Ilias Georgakopoulos-Soares
Candace S Y Chan
Underrepresented k-mer sequences, provide insights into evolutionary constraints, molecular mechanisms, and organismal fitness. Analysis of these sequences have broad applications across genomics and proteomics, such as in biomarker develop...
Sajjad Bakhtiari,Mohammad Rostami-Nejad
Sajjad Bakhtiari
Celiac disease (CD) is a chronic autoimmune disorder triggered by gluten ingestion in genetically predisposed individuals. Current diagnostic methods rely on serological markers, histological examination of duodenal biopsies, and HLA genoty...
Advances in optical biosensors: Technologies and trends in point of care applications [0.03%]
光学生物传感器进展：面向护理点应用的技术和趋势
Alper Baran Sözmen,Ayşe Ezgi Bayraktar,Özgür Ülker et al.
Alper Baran Sözmen et al.
A sensor detects changes in its environment and converts them into readable data using three key components: a receptor to sense changes, a transducer to generate a signal, and a detection system to output the signal. Optical sensors are de...
Gregory S Makowski
Gregory S Makowski