2D-DIGE proteomics [0.03%]
二维差异性等电聚焦凝胶蛋白质组学
Kay Ohlendieck,Paul Dowling
Kay Ohlendieck
Gel electrophoresis is a key technique of modern biochemistry and frequently used for efficient protein separation prior to top-down proteomics. For comparative studies, differential fluorescent tagging can be employed to avoid gel-to-gel v...
Ravi Kumar Sharma,Alpa Singh,Saurabh Dawra
Ravi Kumar Sharma
Pancreatogenic diabetes, i.e. Type 3c Diabetes Mellitus (T3c), is a distinct clinical entity primarily caused by underlying pancreatic disorders. These include acute, chronic, or recurrent pancreatitis, traumatic pancreatitis, pancreatic su...
Monica Ness,Godwin Kwakye-Nuako,Joseane Godinho et al.
Monica Ness et al.
Infectious disease disrupts host metabolism in profound ways, producing distinct small molecule signatures that reflect the underlying biological responses to infection. These metabolite changes offer valuable opportunities for biomarker di...
Chrysoula-Evangelia Karachaliou,Evangelia Livaniou
Chrysoula-Evangelia Karachaliou
Autoimmune disease (AD), characterized by abnormal immune system function, leads to self-attack against cells, tissues and organs resulting in increased morbidity and mortality thus contributing to healthcare and socioeconomic expense world...
Mark Woollam,Eray Schulz,Mangilal Agarwal
Mark Woollam
Volatile organic compounds (VOCs) of biological origin represent a promising source of noninvasive biomarkers for a wide range of biomedical applications. These compounds can be detected in various sample types, including breath, urine, blo...
Gregory S Makowski
Gregory S Makowski
Autophagy in lipid metabolism [0.03%]
自噬与脂代谢
Mouliganesh Sekar,Kavitha Thirumurugan
Mouliganesh Sekar
Autophagy is a complex and highly regulated cellular process essential for maintaining homeostasis in adipose tissue by modulating adipocyte differentiation, lipogenesis, and lipolysis. Although lipids are primarily known as energy-storage ...
Stefano Zoroddu,Angelo Zinellu,Ciriaco Carru et al.
Stefano Zoroddu et al.
Inflammation and oxidative stress play a critical pathophysiological role in the onset and the progression of a wide range of chronic disease states that impose a significant public health burden worldwide, e.g., atherosclerosis, cardiovasc...
Naren Das,Arnav Jhalani
Naren Das
Nanopore sensing has developed as a revolutionary analytical tool in clinical chemistry, which facilitates fast, label-free analysis of biomolecules from nucleic acids through proteins and small metabolites. Its potential for converting mol...
Mustapha Zendjabil
Mustapha Zendjabil
MicroRNAs (miRNAs) are experiencing increased interest for their potential as biomarkers and therapeutic agents and targets. In this review, we discuss the various advances in miRNAs detection from sample collection to result interpretation...