Toward a holistic approach for diagnosing sepsis in the emergency department [0.03%]
面向急诊科脓毒症诊断的综合性方法研究
Gianfranco Cervellin,Philipp Schuetz,Giuseppe Lippi
Gianfranco Cervellin
Advances in biomarker detection: Alternative approaches for blood-based biomarker detection [0.03%]
生物标志物检测新进展：基于血液的生物标志物检测的替代方法
Miguel Rosado,Rafael Silva,Mariana G Bexiga et al.
Miguel Rosado et al.
In the clinical setting, a blood sample is typically the starting point for biomarker search and discovery. Mass spectrometry (MS) is a highly sensitive and informative method for characterizing a very wide range of metabolites and proteins...
Andrei C Sposito,Francesca Zimetti,Joaquim Barreto et al.
Andrei C Sposito et al.
The reduction of plasma apolipoprotein B (apoB) containing lipoproteins has long been pursued as the main modifiable risk factor for the development of cardiovascular disease (CVD). This has led to an intense search for strategies aiming at...
Elif Burcu Aydin,Muhammet Aydin,Mustafa Kemal Sezgintürk
Elif Burcu Aydin
Immunosensors are compact tools on which antibody and antigen interactions are formed. The specific interaction between antibody and antigen is detected by using a transducer and an electrical signal is measured. This specific interaction b...
Gregory S Makowski
Gregory S Makowski
En C Fung,Asif N Butt,Jarlath Eastwood et al.
En C Fung et al.
Acute myocardial infarction (AMI) and heart failure (HF) are two major causes of cardiovascular mortality and morbidity. Early diagnosis of these conditions is essential to instigate immediate treatment that may result in improved outcomes....
Hong Zhou,Jing Liu,Jing-Juan Xu et al.
Hong Zhou et al.
Specific nucleic acid detection in vitro or in vivo has become increasingly important in the discovery of genetic diseases, diagnosing pathogen infection and monitoring disease treatment. One challenge, however, is that the amount of target...
Debolina Chakraborty,Chandrasekaran Natarajan,Amitava Mukherjee
Debolina Chakraborty
High incidence of oral carcinoma and its late-stage presentation are the major global healthcare issues. The World Health Organization (WHO) has set early diagnosis and prevention of oral cancer as their primary objective. It is important t...
Alexandru Zlibut,Ioana Corina Bocsan,Lucia Agoston-Coldea
Alexandru Zlibut
Pentraxin 3 (PTX3) is involved in vascular inflammation and endothelial dysfunction through various mechanisms. Until now, most studies confirmed an important link between PTX3 and endothelial dysfunction and identified several pathogenetic...
Advances in HER2 testing [0.03%]
HER2检测的进展
Yun Chen,Liang Liu,Ronghua Ni et al.
Yun Chen et al.
HER2-positive breast cancer is a particularly aggressive type of breast cancer. Indication of HER2 positivity is essential for its treatment. In addition to a few FDA-approved methods such as immunohistochemical (IHC) detection of HER2 prot...