Saradha Baskaran,Manesh Kumar Panner Selvam,Ashok Agarwal
Saradha Baskaran
Exosomes are nanosized membrane vesicles secreted by wide variety of cells and found in abundance in biological fluids including semen. They contain cargo of lipids, proteins, microRNAs and mRNAs, and are known to play a major role in intra...
Ramesh Choudhari,Melina J Sedano,Alana L Harrison et al.
Ramesh Choudhari et al.
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key players in biological regulation; however, the mechanisms by which lncRNAs govern various disease processes remain mysterious and are just beginning to be unde...
Alison Burklund,Amogha Tadimety,Yuan Nie et al.
Alison Burklund et al.
Microfluidics is an emerging field in diagnostics that allows for extremely precise fluid control and manipulation, enabling rapid and high-throughput sample processing in integrated micro-scale medical systems. These platforms are well-sui...
Gregory S Makowski
Gregory S Makowski
Jacopo Troisi,Pierpaolo Cavallo,Angelo Colucci et al.
Jacopo Troisi et al.
Metabolomics is an intriguing field of study providing a new readout of the biochemical activities taking place at the moment of sampling within a subject's biofluid or tissue. Metabolite concentrations are influenced by several factors inc...
Clotting factors: Clinical biochemistry and their roles as plasma enzymes [0.03%]
凝血因子：临床生化及其作为血浆酶的作用
William E Winter,Dina N Greene,Stacy G Beal et al.
William E Winter et al.
The purpose of this review is to describe structure and function of the multiple proteins of the coagulation system and their subcomponent domains. Coagulation is the process by which flowing liquid blood plasma is converted to a soft, visc...
Organokines in disease [0.03%]
疾病中的器官细胞因子的作用
Hye Soo Chung,Kyung Mook Choi
Hye Soo Chung
Studies have linked obesity, metabolic syndrome, type 2 diabetes, cardiovascular disease (CVD), nonalcoholic fatty liver disease (NAFLD) and dementia. Their relationship to the incidence and progression of these disease states suggests an i...
Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance [0.03%]
表观遗传重编程及表观遗传修饰药物在获得性化疗耐药中的潜在应用
Logeswari Ponnusamy,Prathap Kumar S Mahalingaiah,Kamaleshwar P Singh
Logeswari Ponnusamy
Chemotherapy is the most common clinical choice of treatment for cancer, however, acquired chemoresistance is a major challenge that limits the successful outcome of this option. Systematic review of in vitro, in vivo, preclinical and clini...
Marta Gomarasca,Giuseppe Banfi,Giovanni Lombardi
Marta Gomarasca
Bone and skeletal muscle are integrated organs and their coupling has been considered mainly a mechanical one in which bone serves as attachment site to muscle while muscle applies load to bone and regulates bone metabolism. However, skelet...
Hypertensive disorders of pregnancy: Strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of this syndrome [0.03%]
妊娠高血压疾病：开发临床肽生物标志物以更准确评估该综合征病理生理状态的策略
Yoshihiko Araki,Mitsuaki Yanagida
Yoshihiko Araki
Hypertensive disorders of pregnancy (HDP) is the most common and widely known as serious complication of pregnancy. As this syndrome is a major leading cause of maternal, fetal, and neonatal morbidity/mortality worldwide, many studies have ...