Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in kidney disease [0.03%]
肾脏疾病中的基质金属蛋白酶和基质金属蛋白酶组织抑制剂
Oskar Zakiyanov,Marta Kalousová,Tomáš Zima et al.
Oskar Zakiyanov et al.
Matrix metalloproteinases (MMPs) are a group of zinc and calcium endopeptidases which cleave extracellular matrix (ECM) proteins. They are also involved in the degradation of cell surface components and regulate multiple cellular processes,...
Lisa Di Medio,Maria Luisa Brandi
Lisa Di Medio
Bone fragility fractures remain an important worldwide health and economic problem due to increased morbidity and mortality. The current methods for predicting fractures are largely based on the measurement of bone mineral density and the u...
IgG N-glycans [0.03%]
IgG N-糖链
Si Liu,Xin Liu
Si Liu
Glycosylation, one of the most common post-translational modifications in mammalian cells, impacts many biological processes such as cell adhesion, proliferation and differentiation. As the most abundant glycoprotein in human serum, immunog...
Gregory S Makowski
Gregory S Makowski
Keiko Hosohata
Keiko Hosohata
High salt intake is associated with hypertension, which is a leading modifiable risk factor for cardiovascular disease (CVD) and chronic kidney disease (CKD). International Guidelines recommend a large reduction in the consumption of sodium...
Cryoglobulins: Identification, classification, and novel biomarkers of mysterious proteins [0.03%]
cryoglobulin：识别、分类以及神秘蛋白质的新生物标志物
Cecilia Napodano,Francesca Gulli,Gian Ludovico Rapaccini et al.
Cecilia Napodano et al.
Cryoglobulins consist of serum immunoglobulins that precipitate below 37°C and resolubilize upon warming. The clinical triad of cryoglobulinemia usually includes purpura, weakness, and arthralgia. Cryoglobulinemic syndrome, clinically defi...
Hao Ding,Lu Zhang,Qian Yang et al.
Hao Ding et al.
Epigenetics examines heritable changes in DNA and its associated proteins except mutations in gene sequence. Epigenetic regulation plays fundamental roles in kidney cell biology through the action of DNA methylation, chromatin modification ...
Rohan Gupta,Rashmi K Ambasta,Pravir Kumar
Rohan Gupta
Neuroepigenetics, a new branch of epigenetics, plays an important role in the regulation of gene expression. Neuroepigenetics is associated with holistic neuronal function and helps in formation and maintenance of memory and learning proces...
Jacopo Troisi,Annamaria Landolfi,Pierpaolo Cavallo et al.
Jacopo Troisi et al.
Parkinson's disease (PD) is a multifactorial neurodegenerative disorder in which environmental (lifestyle, dietary, infectious disease) factors as well as genetic make-up play a role. Metabolomics, an evolving research field combining bioma...
Brian Regan,Richard O&#x;Kennedy,David Collins
Brian Regan
Point-of-care testing (POCT) is a specific format of diagnostic testing that is conducted without accompanying infrastructure or sophisticated instrumentation. Traditionally, such rapid sample-to-answer assays provide inferior analytical pe...