Molecular and cellular functions of long non-coding RNAs in prostate and breast cancer [0.03%]
长非编码RNA在前列腺癌和乳腺癌中的分子与细胞功能作用
Yuan-Shan Zhu,Jifeng Zhu
Yuan-Shan Zhu
Long noncoding RNAs (lncRNAs) are defined as noncoding RNA transcripts with a length greater than 200 nucleotides. Research over the last decade has made great strides in our understanding of lncRNAs, especially in the biology of their role...
Ahmed Ismaeel,Ramon Lavado,Panagiotis Koutakis
Ahmed Ismaeel
The science of metabolomics has emerged as a novel tool for studying changes in metabolism that accompany different disease states. Several studies have applied this evolving field to the study of various cardiovascular disease states, whic...
Stefano Ciardullo,Gianluca Perseghin
Stefano Ciardullo
Nonalcoholic fatty liver disease (NAFLD) affects a quarter of the adult world population and the degree of liver fibrosis represents the best predictor of the development of liver-related outcomes. Easily applicable and well performing non-...
Metadherin (AEG-1/MTDH/LYRIC) expression: Significance in malignancy and crucial role in colorectal cancer [0.03%]
Metadherin(AEG-1/MTDH/LYRIC)的表达：恶性肿瘤的意义及结直肠癌中的关键作用
Muhammad T Abdel Ghafar,Nema A Soliman
Muhammad T Abdel Ghafar
Metadherin (AEG-1/MTDH/LYRIC) is a 582-amino acid transmembrane protein, encoded by a gene located at chromosome 8q22, and distributed throughout the cytoplasm, peri-nuclear region, nucleus, and nucleolus as well as the endoplasmic reticulu...
Pasquale Esposito,Daniela Picciotto,Yuri Battaglia et al.
Pasquale Esposito et al.
Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed by animal and human skeletal muscle cells where it limits muscle growth and promotes protein breakdown. Its effects are influenced by complex mech...
Rahel Schnellmann
Rahel Schnellmann
A Disintegrin and Metalloproteinase with Thrombospondin motifs (ADAMTS) are major mediators in extracellular matrix (ECM) turnover and have gained increasing interest over the last years as major players in ECM remodeling during tissue home...
Gregory S Makowski
Gregory S Makowski
Jian Yang,Xue Zou,Pedro A Jose et al.
Jian Yang et al.
Extracellular vesicles (EVs) have received considerable attention in biological and clinical research due to their ability to mediate cell-to-cell communication. Based on their size and secretory origin, EVs are categorized as exosomes, mic...
Bela Barros,Marta Oliveira,Simone Morais
Bela Barros
Firefighters are the professional force at high risk of suffering potential health consequences due to their chronic exposure to numerous hazardous pollutants during firefighting activities. Unfortunately, determination of fire emission exp...
Benjamín Rubio-Jurado,Lluvia Sugey Sosa-Quintero,Sandra Guzmán-Silahua et al.
Benjamín Rubio-Jurado et al.
Neoplasms result from changes in the mechanisms of growth, differentiation, and cellular death. Cancers are of high clinical relevance due to their prevalence and associated morbidity and mortality. The clinical and biological diversity of ...