Iyyapu Krishna Mohan,K S S Sai Baba,Rohit Iyyapu et al.
Iyyapu Krishna Mohan et al.
Congestive heart failure (CHF) is the leading cause of morbidity and mortality in the elderly worldwide. Although many biomarkers associated with in heart failure, these are generally prognostic and identify patients with moderate and sever...
Immune checkpoint therapy and response biomarkers in non-small-cell lung cancer: Serum NY-ESO-1 and XAGE1 antibody as predictive and monitoring markers [0.03%]
非小细胞肺癌的免疫检查点治疗和应答生物标志物：血清NY-ESO-1 和XAGE1 抗体作为预测和监测标记物
Koji Kurose,Kanako Sakaeda,Minoru Fukuda et al.
Koji Kurose et al.
Immune checkpoint inhibitors (ICI) are key drugs in systemic therapy for advanced non-small-cell lung cancer (NSCLC) and have recently been incorporated into neoadjuvant and adjuvant settings for surgical resection. Currently, ICI combinati...
Translational proteomics and phosphoproteomics: Tissue to extracellular vesicles [0.03%]
转化蛋白质组学和磷酸化蛋白质组学：组织到细胞外囊泡
Xiaofeng Wu,Anton B Iliuk,W Andy Tao
Xiaofeng Wu
We are currently experiencing a rapidly developing era in terms of translational and clinical medical sciences. The relatively mature state of nucleic acid examination has significantly improved our understanding of disease mechanism and th...
Heterogeneity in major depressive disorder: The need for biomarker-based personalized treatments [0.03%]
重度抑郁症的异质性：需要基于生物标志物的个性化治疗
Shayam Suseelan,Graziano Pinna
Shayam Suseelan
Major Depressive Disorder (MDD) or depression is a pathological mental condition affecting millions of people worldwide. Identification of objective biological markers of depression can provide for a better diagnostic and intervention crite...
Gregory S Makowski
Gregory S Makowski
Luis Perpetuo,Rita Ferreira,Visith Thongboonkerd et al.
Luis Perpetuo et al.
Exosomes are tiny membrane-enveloped vesicles of endosomal origin, typically 40-120nm in diameter, produced by most cells in both normal and pathological situations. These exosomes can be isolated from all biofluids, including urine. In thi...
Roy R Gerona,Deborah French
Roy R Gerona
Traditional clinical toxicology involves the analysis of patient urine samples by immunoassays designed to detect opiates/opioids, amphetamine/methamphetamine, benzodiazepines, barbiturates, cocaine metabolite and tetrahydrocannabinol. Expa...
Anastasia Bougea,Leonidas Stefanis,George Chrousos
Anastasia Bougea
Parkinson's disease (PD) is characterized by complex motor and non-motor symptoms that vary in onset, severity, response to treatment, and disability. The unpredictable and debilitating nature of PD and the inability to halt or slow disease...
Lei Liu,Xue Yao,Yanrong Wang et al.
Lei Liu et al.
The physin family of proteins, synaptophysin (SYP), synaptophysin like 1 (SYPL1), synaptophysin like 2 (SYPL2) and synaptoporin (SYNRP), are tetratransmembrane transport vesicle proteins distributed throughout the digestive system. Of these...
Young-Hye Cho,Youngin Lee,Jung In Choi et al.
Young-Hye Cho et al.
Metabolic syndrome (MetS) is a global health challenge characterized as a group of risk factors for developing atherosclerotic cardiovascular disease. Although visceral adipose tissue, adipocyte dysfunction, chronic low-grade inflammation, ...