Development of a Prognostic Model for Gastric Cancer Based on Apoptosis- and Hypoxia-Related Genes: Predictive Insights into Survival and Immune Landscape [0.03%]
基于凋亡和缺氧相关基因的胃癌预后模型的建立：生存和免疫景观的预测洞察
Jian Zhu,Yao Ma
Jian Zhu
Gastric cancer (GC) is the fifth most prevalent malignancy worldwide, characterized by poor prognosis. Apoptosis is interacted with hypoxia in tumorigenesis. This study attempted to delineate potential value of apoptosis and hypoxia-related...
RNF20 Reduces Cell Proliferation and Warburg Effect by Promoting NLRP3 Ubiquitination in Liver Cancer [0.03%]
RNF20通过促进NLRP3泛素化抑制肝癌细胞增殖和瓦博格效应
Deqin Liu,Renyin Luo,Qian Zhou et al.
Deqin Liu et al.
The present study explored that the effects and its possible mechanisms of ring finger protein 20 (RNF20) in Postoperative survival rate of liver cancer in clinical. All the serum samples were collected from our hospital. Quantitative polym...
Prognostic Significance of Iron Metabolism and Immune-Related Genes as Risk Markers in Hepatocellular Carcinoma [0.03%]
铁代谢和免疫相关基因在肝细胞癌中的预后价值及作为生物标志物的潜力
Shijing Tang,Hao Chen
Shijing Tang
Hepatocellular carcinoma (HCC) is a highly lethal liver cancer with significant heterogeneity, which poses challenges in predicting prognosis and treatment outcomes. The impact of iron metabolism and immune-related genes (IMRGs) on HCC pati...
Treatment Strategy for Breast Benign Intraductal Papilloma: A Meta-Analysis [0.03%]
乳腺导管内乳头状瘤的治疗策略meta分析
Congkun Lou,Wenhsin Wang,Binggang Zhou
Congkun Lou
Currently, the optimal treatment approach for breast benign intraductal papilloma (IDP) diagnosed via biopsy remains uncertain. There is ongoing debate regarding the feasibility of clinical follow-up and the criteria for selective surgical ...
Molecular Pathogenesis, Organ Metastasis, and Targeted Therapy for Non-Small-Cell Lung Cancer [0.03%]
非小细胞肺癌的分子发病学、器官转移和靶向治疗
Salik Abdullah,Ratul Chakraborty,Pratiksha Somnath Kumkar et al.
Salik Abdullah et al.
Around 2 million people are diagnosed with lung cancer annually, causing 20,000 deaths. Non-small cell carcinomas account for 80-85% of lung cancer cases. Over the last few decades, there has been an improved understanding of the chromosoma...
Sanjib Bhattacharya
Sanjib Bhattacharya
Protease is the enzyme accountable for the breakdown of proteins i.e., proteolysis. Proteases are reportedly involved in the events of growth, development, progression and metastasis of cancers. If any agent could inhibit/retard the proteas...
Probing the Potential: Exploring Probiotics as a Novel Frontier in Cancer Prevention and Therapeutics [0.03%]
探求潜力：探究益生菌在癌症预防和治疗中的新前沿
Akhil Nair,Kanchanlata Tungare,Ameyota De et al.
Akhil Nair et al.
Cancer has emerged as one of the most prevalent diseases worldwide, with a consistent rise in the number of cases observed over the past few decades. The rising mortality rates associated with cancer have transformed it into a significant g...
Alok Ghosh Chaudhuri,Saptadip Samanta,Monalisha Dey et al.
Alok Ghosh Chaudhuri et al.
Alpha-fetoprotein (AFP) belongs to the albuminoid protein family and is considered as the fetal analog of serum albumin. This plasma protein is initially synthesized in the fetal liver and yolk sac and shows a maximum peak near the end of t...
A Systems Biology Approach Unveils a Critical Role of DPP4 in Upper Gastrointestinal Cancer Patient Outcomes [0.03%]
系统生物学方法揭示DPP4在上消化道癌症患者预后中的关键作用
Sudhir Kotnala,Anupam Dhasmana,Swati Dhasmana et al.
Sudhir Kotnala et al.
Gastrointestinal (GI) cancers comprise of cancers that affect the digestive system and its accessory organs. The late detection and poor prognosis of GI cancer emphasizes the importance of identifying reliable and precise biomarkers for ear...
Withaferin A-Encapsulated PEGylated Nanoliposomes Induce Apoptosis in B16F10 Melanoma Cells by Regulating Bcl2 and Bcl xl Genes and Mitigates Murine Solid Tumor Development [0.03%]
富含Withaferin A的PEG修饰纳米脂质体通过调节Bcl2和Bcl-xl基因诱导B16F10黑色素瘤细胞凋亡并减轻小鼠实体肿瘤的发生发展
Prathapan Abeesh,Chandrasekharan Guruvayoorappan
Prathapan Abeesh
Withaferin A (WA) is a natural steroidal lactone with promising pharmacological activities, but its poor solubility and bioavailability hinder its clinical application. The liposomal drug delivery system has attracted considerable attention...