Downregulation of miR-605-5p Facilitates Breast Cancer Progression and Predicts Unfavorable Prognosis [0.03%]
miR-605-5p表达沉默促进乳腺癌进展并预示不良预后
Cong Meng,Yuemian Liang,Hubao Yuan et al.
Cong Meng et al.
Breast cancer (BC) is one of the main causes of cancer-related death in women. The purpose of this study was to evaluate the expression of miR-605-5p in BC and its diagnostic and prognostic value. BC patients and healthy individuals who met...
lncRNA-miRNA/RBP-mRNA Network Involved in Human Triple-Negative Breast Cancer: An Integrated Approach [0.03%]
用于研究人类三阴性乳腺癌的lncRNA-miRNA/RBP-mRNA网络的集成方法
Wen Yun,Yao Li,Jianyuan Huang et al.
Wen Yun et al.
Noncoding RNA regulatory networks play crucial roles in human breast cancer. The aim of this study was to establish a network containing multi-type RNAs and RBPs in triple-negative breast cancer (TNBC). Differential expression analyses of l...
Histone Methyltransferase EHMT2 Promotes the Progression of Breast Ductal Carcinoma by Regulating the Hippo Pathway [0.03%]
组蛋白甲基转移酶EHMT2通过调节Hippo信号通路促进乳腺导管癌进展
Ying Xiao,Lin Song,Wen-Jing Xie et al.
Ying Xiao et al.
Invasive ductal carcinoma (IDC) is a major type of breast cancer. The utilization of inhibitors targeting histone methyltransferases introduces novel therapeutic avenues for the treatment of cancer. Immunohistochemistry, Western blot, and r...
Inhibition of Interleukin-1 Receptor-Associated Kinase-1 by Pacritinib Is a Therapeutic Strategy to Overcome Melanoma Resistance [0.03%]
帕克替尼抑制白细胞介素-1受体相关激酶-1是克服黑色素瘤耐药性的治疗策略
Li Ma,Yue Ruan,Mei Cao et al.
Li Ma et al.
Despite advancements in systemic therapy, the mortality rate for patients with metastatic melanoma remains around 70%, underscoring the imperative for alternative treatment strategies. Through the establishment of a chemoresistant melanoma ...
Inflammatory Gene Variants and Protein Levels: An Important Predictor of Prostate Cancer Development [0.03%]
炎症基因变异及蛋白水平：一项重要的前列腺癌发病预测指标研究
Emine Yagci,Hulyam Kurt,Ata Ozen et al.
Emine Yagci et al.
Prostate cancer and inflammation mechanism are closely related because chronic inflammation causes inflammatory cells to infiltrate into prostatic atrophy areas and proliferative inflammatory atrophy is accepted as the initiator of prostate...
Ethyl Acetate Extract of Oratosquilla Inhibits the Growth of Nasopharyngeal Carcinoma through the Hippo Pathway [0.03%]
乙酰基奥拉托斯卡抑制喉癌生长的 hippo 信号通路机制研究
Huaigao Wang,Zhuofei Jiang,Mengjie Shi et al.
Huaigao Wang et al.
The Hippo pathway and its transcription co-activator YAP play a critical role in the regulation of cell proliferation, apoptosis and the control of organ size. In the past several years, YAP has been found to be expressed in various human c...
Biochemical Ferrous Ions (Fe2+) Mediated Fenton Reaction: A Biological Prodigy for Curing and Developing Autoimmune Rheumatoid Arthritis and Cancer [0.03%]
生化亚铁离子（Fe2+）介导的芬顿反应：一种治疗和开发自身免疫性类风湿关节炎和癌症的生物学奇才
Asis Bala
Asis Bala
Iron is an essential trace element for the human body, but having too much or too little of it can cause various biological issues. When ferrous ions react with hydrogen peroxide, they create highly reactive and soluble hydroxyl radicals th...
Molecular Mechanism of Long Non-Coding RNAs in Ovarian Cancer: CASC19 Regulates the Malignant Progression of Ovarian Cancer through miR-761/CBX2 Axis [0.03%]
长非编码RNA分子机制与卵巢癌发生发展关系的研究:CASC19通过miR-761/CBX2轴调控卵巢癌恶性进展
KharChuen Wong,Peng Dai,Yuan Li et al.
KharChuen Wong et al.
Long non-coding RNAs (lncRNAs) are involved in the numerous types of tumors. The aim of this study is to comprehend the pathological mechanism of lncRNA CASC19 in ovarian cancer. CASC19, miR-761 and CBX2 expression in the samples was quanti...
The Long Non-Coding RNA linc01105 Inhibits Gastric Cancer Growth and Metastasis by Regulating the miR-650/TCEA3 Axis [0.03%]
长链非编码RNA linc01105通过调节miR-650/TCEA3轴抑制胃癌生长和转移
Qiang Zhang,Hui Mi,Huimei Cai et al.
Qiang Zhang et al.
Gastric cancer (GC) is a widespread cancerous disease with an unfavorable prognosis, linc01105 appears to have a significant connection with the development of GC, but the precise regulatory mechanism remains obscure. Real-time quantitative...
Identifying circRNA-miRNA-mRNA Networks Associated with Osimertinib Resistance in Lung Adenocarcinoma by Analyzing Microarray Datasets [0.03%]
通过分析微阵列数据集识别与奥希替尼耐药相关的环状RNA- microRNA- mRNA网络在肺腺癌中的作用
Fen Liu,Xiyan Wang,Wenjun Tian et al.
Fen Liu et al.
Background: This study was to screen for circRNAs associated with osimertinib resistance in lung adenocarcinoma (LUAD) and establish a circRNA-miRNA-mRNA ceRNA network. ...