Anti-Cancer Role of Ellagic Acid by Modulating the Altered PI3K/PTEN/Akt Pathway in Bladder Cancer [0.03%]
通过调节PI3K / PTEN / Akt途径的改变发挥抗肿瘤作用的ellagic酸在膀胱癌中的作用
Satya Sahay,Deepika Trehan,Ranbala Kumari et al.
Satya Sahay et al.
Bladder cancer (BCa) is approximately the fourth most prevalent diagnosed cancer in men and is three times less common in women. Therefore, identifying biomarkers, developing more effective therapeutic strategies, and understanding the mech...
Identification of Ion Channel-Associated Prognostic Biomarkers for Lung Adenocarcinoma [0.03%]
肺癌腺癌离子通道相关预后生物标志物的识别
Yunfei Liu,Yanpeng Wang,Taoli Chen et al.
Yunfei Liu et al.
Expression and functional dysregulation of ion channel genes are correlated with an unfavorable prognosis in lung adenocarcinoma (LUAD). Ion channel signature for predicting the prognosis of individuals with LUAD. 94 ion channel-related dif...
lncRNA PTCSC1 Promotes TRAIL Resistance through FOXO3a Pathway in HCT116 and SW480 Cells [0.03%]
长链非编码RNA PTCSC1通过FOXO3a途径促进HCT116和SW480细胞对TRAIL的抵抗作用
Changcheng Wang,Jia Guo,Zengan Wu
Changcheng Wang
Colorectal cancer (CRC) is a malignant tumor that affects patients worldwide, and its mortality rate is high. Although treatments that activate TNF-associated apoptosis-inducing ligand (TRAIL)-induced apoptosis have shown some efficacy, man...
Identification of Lung Adenocarcinoma Subtypes Using Growth Hormone-Releasing Hormone-Related Genes and Establishment of Signature to Predict Prognosis and Guide Immunotherapy [0.03%]
基于生长激素释放素相关基因的肺腺癌亚型识别及预后判断和指导免疫治疗标志物建立
Kai Zhu,Zhenwu Xu,Xue Peng et al.
Kai Zhu et al.
Growth hormone-releasing hormone (GH-RH) and its antagonists are believed to influence the progression of various tumor diseases. However, the specific effects of GH-RH-related genes on lung adenocarcinoma (LUAD) are yet to be deciphered. G...
Exploring Gene-Regulatory Networks and Potential Therapeutic Drugs Based on ELF3 Expression in Cholangiocarcinoma [0.03%]
基于ELF3表达探索胆管癌中的基因调控网络及潜在治疗药物
Cui Zhang,Mengting Tong,Guangpeng Chen et al.
Cui Zhang et al.
Cholangiocarcinoma (CCA) is a life-threatening malignancy, and there is an urgent need for new biomarkers to improve the prognosis of patients. The expression of ELF3 in CCA tumor and non-tumor tissues was examined in two cohorts. ELF3 expr...
Ethnopharmacology, genetic diversity, phytochemistry and pharmacological effects of Panax vietnamensis Ha et Grushv.: A review [0.03%]
越南参的民族药理学、遗传多样性、植物化学和药理效应综述
Tran Hoang Ngau,Chau Phan Kim Dieu,Chau Phan Kim Hue et al.
Tran Hoang Ngau et al.
Ginseng is considered as a beneficial herbal remedy and over recent years its efficacy and safety have been verified in clinical therapy. There are two typical species of ginseng including Asian and American ginseng. The varieties of both s...
PRMT4 Reduced Erastin-Induced Ferroptosis in Nasopharyngeal Carcinoma Cisplatin-Resistant Cells by Nrf2/GPX4 Pathway [0.03%]
脯氨酰-tRNA合成酶4通过Nrf2/GPX4信号通路减少咽部癌细胞中艾拉斯汀诱导的铁死亡
Xiaoping Pu,Hong Wu,Xiaoyan Liu et al.
Xiaoping Pu et al.
Nasopharyngeal carcinoma (NPC) is one of the common malignant tumors in clinic. In the current study, we aim to investigate the effects of PRMT4 on erastin-induced ferroptosis in NPC by cisplatin resistant. PRMT4 expression in patients with...
HIF-1α Activates Hypoxia-Induced MXRA5 Expression in the Progression of Ovarian Cancer [0.03%]
低氧诱导因子HIF-1α通过调控MXRA5基因表达促进卵巢癌进展的作用及机制研究
Liju Nie,Linfeng Huang,Qizhou Zhu et al.
Liju Nie et al.
The hypoxic microenvironment of tumor cells is closely related to the progression of ovarian cancer (OV). Hypoxia (HY)-related matrix-remodeling associated 5 (MXRA5) was expressed at elevated levels in many tumors, but research on the impac...
Analysis of the Clinical Value of hsa_circ_0001955 in Papillary Thyroid Cancer Treated with 131 Iodine [0.03%]
分析hsa_circ_0001955在碘-131治疗乳头状甲状腺癌中的临床价值
Chong Cheng,Ling Zhang,Quanyong Wang et al.
Chong Cheng et al.
The prevalent histological variant within differentiated thyroid carcinoma is papillary thyroid carcinoma, also known as PTC. The study investigated the clinical performance of serum hsa_circ_0001955 in predicting the prognosis of PTC treat...
Histone-Lysine N-Methyltransferase 2D (KMT2D) Impending Therapeutic Target for the Management of Cancer: The Giant Rats Tail [0.03%]
组蛋白赖氨酸N-甲基转移酶2D（KMT2D）有望成为癌症管理的治疗靶点：巨大的老鼠尾巴
Meshak Dhanashekaran Cecileya Jasmin,Narayanaswamy Radhakrishnan,Venugopal Vinod Prabhu et al.
Meshak Dhanashekaran Cecileya Jasmin et al.
The histone-lysine N-methyltransferase 2D (KMT2D), tumor suppressor gene which is the major component of histone H3K4 mono-methyltransferase in mammals and has significant role in regulation of a gene which are frequently mutated that lead ...