Effects of RNA Modification "Writers" of GALNT2 on the Tumor Microenvironment in Cervical Squamous Cell Carcinoma [0.03%]
GALNT2修饰"书写者"对宫颈鳞癌肿瘤微环境的影响
Shizhang Wang,Lin Chen
Shizhang Wang
Cervical squamous cell carcinoma (CESC) is one of the most common causes of cancer-related deaths in women. RNA modification "writers" modulate and alter RNA molecular activity and have been implicated in the origin and development of cance...
miR-210-3p Impairs Pancreatic β-Cell Function by Targeting Dtx1 in Gestational Diabetes Mellitus [0.03%]
miR-210-3p通过靶向Dtx1损害妊娠糖尿病的胰岛β细胞功能
Xiaohui Cao,Bin Lu,Ying Gu et al.
Xiaohui Cao et al.
Gestational diabetes mellitus (GDM), a common complication in pregnancy, could threaten the health of both pregnancies and their offspring. miR-210-3p has been reported that play a crucial role in many diseases. Nevertheless, the molecular ...
Peng Hu,Jinwei Guo,Benhuo Zhao et al.
Peng Hu et al.
Inactivation of hepatic stellate cells (HSCs) slows down liver cirrhosis (LC) advancement. The role of circular RNAs (circRNAs) in LC is largely undiscovered. Here, we clarified the effect of circCHD2 on HSCs. LX-2 cells were stimulated wit...
Oncogenic Role of Heterogeneous Nuclear Ribonucleoprotein C in Multiple Cancer Types, with a Particular Focus on Lung Adenocarcinoma, Using a Pan-Cancer Analysis and Cell Line Experiments [0.03%]
泛癌分析和细胞系实验在多种癌症类型中探究hnRNP C的致癌作用（以肺腺癌为主）
Libin Zhang,Hao Peng,Lihong Jiang
Libin Zhang
Although some evidence has validated the connection between heterogeneous nuclear ribonucleoprotein C (HNRNPC) and the progression of tumors, a pan-cancer investigation is still required. Thus, we explored the oncogenic effect of HNRNPC acr...
miR-1246 Promotes Laryngeal Squamous Cell Carcinoma Progression by Interacting with THBS1 [0.03%]
微RNA-miR-1246通过与THBS1相互作用促进喉鳞状细胞癌进展
Lifeng Wu,Na Zuo,Shuo Pan et al.
Lifeng Wu et al.
MicroRNAs (miRNAs) have been confirmed to be related to the occurrence and progress of multiple cancers, including laryngeal squamous cell carcinoma (LSCC). The present work focused on exploring the role of miR-1246 in LSCC and investigatin...
Adverse Effects of COVID-19 Treatments: A Special Focus on Susceptible Populations [0.03%]
COVID-19治疗的不良反应：关注易感人群
Beyza Nur Küçük,Rahime Şimşek,Selinay Başak Erdemli Köse et al.
Beyza Nur Küçük et al.
On December 2019, the world faced a new pandemic caused by a novel type of coronavirus, namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease is named as "coronavirus disease 2019 (COVID-19)." This RNA virus infe...
Sinigrin Impedes the Breast Cancer Cell Growth through the Inhibition of PI3K/AKT/mTOR Phosphorylation-Mediated Cell Cycle Arrest [0.03%]
黑芥子硫苷通过抑制PI3K / AKT / mTOR磷酸化介导的细胞周期停滞来阻碍乳腺癌细胞生长
Shuqin Li,Jiawen Lin,Jiaofei Wei et al.
Shuqin Li et al.
Breast carcinoma, one of the most lethal variants of carcinogenesis, significantly diagnosed type of cancer amongst the female population. Sinigrin, also known as glucosinolate, is found in the seeds of Brassica nigra and shown to enhance v...
Investigating In Vitro and In Vivo Anti-Tumor Activity of Curvularia-Based Platinum Nanoparticles [0.03%]
基于卷曲菌的铂纳米颗粒的体内外抗肿瘤活性研究
Sonali Bhattacharya,Madhusree Halder,Arnab Sarkar et al.
Sonali Bhattacharya et al.
The use of platinum (Pt)-based anticancer drugs, although widespread in clinical practice, is severely limited due to toxic side-effects. One of the strategies for making Pt-based chemotherapy more effective is the synthesis and use of Pt n...
Comprehensive Investigation of Genes Associated with Cell Cycle Pathways for Prognosis and Immunotherapy in Bladder Urothelial Carcinoma [0.03%]
全面调查细胞周期通路相关基因在膀胱尿路上皮癌预后及免疫治疗中的作用
Yue Mi,Xiaowen Wang
Yue Mi
Bladder urothelial carcinoma (BLCA) is estimated to cause approximately 150,000 deaths per year worldwide. The prognosis of BLCA remains dismal, so early detection can have a significant impact on clinical outcomes. Numerous studies have sh...
Ginsenoside Rk2 Protects against Ulcerative Colitis via Inactivating ERK/MEK Pathway by SIRT1 [0.03%]
人参皂苷Rk2通过SIRT1使ERK / MEK失活从而防治溃疡性结肠炎
Xiaodong Huang,Jianwei Xiao,Mudan Wen et al.
Xiaodong Huang et al.
Background: Chinese traditional medicine is widely used in the treatment of ulcerative colitis (UC). Ginsenoside Rk2 is a newly discovered dammarane triterpenoid saponin isolated from ginseng. Our study aimed to investiga...