Serotonergic psychedelics for depression: A comprehensive overview [0.03%]
血清素 Psychedelics 治疗抑郁症：全面概述
A M Wingert,C Agnorelli,J Peill et al.
A M Wingert et al.
Depressive disorders continue to pose a major clinical challenge worldwide, particularly given the high prevalence and increasing number of treatment-resistant cases. Over the past decade, advances in research have elucidated the antidepres...
Potential therapeutic effects of psychedelics in small doses: Is there a role for microdosing in psychiatry? [0.03%]
微量剂量迷幻剂的潜在治疗效果：微剂量在精神病学中的作用是什么？
Iva Totomanova,Eline C H M Haijen,Petra P M Hurks et al.
Iva Totomanova et al.
Clinical trials using full doses of psychedelics have provided preliminary evidence supporting their safety and efficacy in treating a variety of physical and psychological conditions. Anecdotal reports indicate that even very small amounts...
Paul Cumming,Klemens Egger,Gitte M Knudsen
Paul Cumming
Molecular brain imaging by positron emission tomography (PET) and single photon emission computer-tomography (SPECT) entails the mapping of the cerebral distribution of radiopharmaceuticals that track physiological processes such as blood p...
Kate Godfrey,Lisa X Luan,Christopher Timmermann
Kate Godfrey
This chapter reviews the effects of classic psychedelics on human oscillatory brain activity, as measured by resting-state electroencephalography (EEG) and magnetoencephalography (MEG). Across moderate to high doses of LSD, psilocybin, ayah...
Matthew B Wall,Robin L Carhart-Harris
Matthew B Wall
Human neuroimaging with functional Magnetic Resonance Imaging has been a key feature of the current wave of psychedelic research, in both healthy and clinical populations. The available data has suggested that classic psychedelics (psilocyb...
Murugan Sevanan Dr,Shyamjith Manikkoth Dr,Chandrapragasam Vani Dr et al.
Murugan Sevanan Dr et al.
Altered microbiome influence on the enteric neuromuscular system in amyotrophic lateral sclerosis (ALS) [0.03%]
肠道菌群改变对肌萎缩侧索硬化症（ALS）肠神经系统肌肉系统的影响
Sadari Manusha,N Varsha,R Varshini et al.
Sadari Manusha et al.
Amyotrophic lateral sclerosis (ALS) is a neurological disease marked by the degeneration of motor neurons, leading to muscle weakness and paralysis. While the cause of ALS is uncertain, research indicates that changes in the gut microbiome ...
Microbiota dysbiosis impact on the immune system dysregulation in Huntington's disease (HD) [0.03%]
肠道菌群紊乱对亨廷顿舞蹈病免疫系统调节的影响
Papia Acharjee,Shambhu Kumar Prasad,Vishal Vikram Singh et al.
Papia Acharjee et al.
Huntington's disease (HD) is a neurodegenerative disorder characterized by motor, cognitive, and psychiatric impairments caused by Huntingtin (HTT) gene mutations, resulting in the mutant huntingtin (mHTT) protein. Both innate and adaptive ...
Maternal exposure to rubella infection elevates risk of congenital rubella syndrome (CRS) [0.03%]
母体感染风疹病毒会导致儿童先天性风疹综合征(CRS)风险升高
Sasikumar Pitchaikani,Pothiaraj Govindan,Harshavardhan Shakila
Sasikumar Pitchaikani
The rise in neurodevelopmental disorders linked to maternal viral infections, particularly during the first and second trimesters of pregnancy, is concerning. Rubella, a contagious viral disease, primarily affects children and young adults,...
Nitin Kumar Singh,Varsha Gupta,Siddhartha Kumar Mishra
Nitin Kumar Singh
Acute Disseminated Encephalomyelitis (ADEM) is an autoimmune condition frequently caused by infections or immunisation activities and is characterised by inflammation and demyelination in the central nervous system (CNS). It primarily affec...