Ali A Habib,Anna Rostedt Punga
Ali A Habib
The diagnostic workup for myasthenia gravis extends beyond the objective evaluation of skeletal muscle fatigue during neurological examinations. It incorporates antibody testing, electrophysiological studies to confirm neuromuscular transmi...
Carolina Barnett Tapia,Anna Rostedt Punga
Carolina Barnett Tapia
The diagnostic precision of MG, along with the emergence of novel treatments targeting the autoimmune response, has ushered the field into a new era, moving MG management closer to personalized medicine. However, critical gaps remain, inclu...
Simone Birnbaum,Linda Kahr Andersen
Simone Birnbaum
The role of non-pharmacological management in MG is currently underdeveloped and underutilized. Exercise training has been shown to be both feasible and beneficial in improving function and strength in individuals with MG. Observational stu...
Michael K Hehir,James F Howard Jr
Michael K Hehir
Treatment options for patients with myasthenia gravis (MG) are rapidly increasing. Seven new MG therapies across 2 novel classes have been approved by the FDA to treat MG; a robust treatment pipeline spans at least 7 novel therapeutic class...
Pushpa Narayanaswami,Ryan Verity,John Vissing
Pushpa Narayanaswami
Advances in immunology over the last several years have provided insights into the pathophysiology of autoimmune diseases such as generalized myasthenia gravis (gMG). This has translated into the development of effective, rapidly acting, an...
Vera Bril,Elham Saedi
Vera Bril
Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by fluctuating muscle weakness due to impaired neuromuscular transmission. Despite therapeutic advances, acute exacerbations and myasthenic crises remain significant chal...
Valentina Damato,Francesca Beretta
Valentina Damato
Myasthenia gravis (MG) is the prototypical disorder of the neuromuscular junction. The clinical hallmarks of MG are fatigability and fluctuating voluntary muscle weakness. Although MG can potentially affect any muscle, some muscle groups ar...
Anna Rostedt Punga,Carolina Barnett-Tapia
Anna Rostedt Punga
Miriam L Fichtner,Lillith Horstkorte,Blanca G Sánchez Navarro et al.
Miriam L Fichtner et al.
Autoimmune Myasthenia Gravis (MG) is a disease characterized by fatigable muscle weakness and autoantibodies. It can be divided by the presence of serum autoantibodies into two major categories where Immunoglobulin G (IgG) against either th...
Nadine Dragin,Rozen Le Panse
Nadine Dragin
The thymus is a central lymphoid organ responsible for T-cell development and maturation and is crucial in adaptive immunity. This organ creates a specialized environment for thymocyte differentiation and positive/negative selection, ensuri...