Hari Shanker Sharma
Hari Shanker Sharma
Vascular endothelial growth factor and other angioglioneurins: key molecules in brain development and restoration [0.03%]
血管内皮生长因子及其他管周神经元因子：脑发育与修复的关键分子
José Vicente Lafuente,Naiara Ortuzar,Harkaitz Bengoetxea et al.
José Vicente Lafuente et al.
Angioneurines are a family of molecules that include vascular growth factors such as VEGF, neurotrophins such as BDNF, IGF-I, and Erythropoietin, among others. They affect both neural and vascular processes. Due to the fact that all of them...
Stephen D Skaper
Stephen D Skaper
Alzheimer's disease (AD) is the largest unmet medical need in neurology today. This most common form of irreversible dementia is placing a considerable and increasing burden on patients, caregivers, and society, as more people live long eno...
Neuroprotective effects of cerebrolysin, a combination of different active fragments of neurotrophic factors and peptides on the whole body hyperthermia-induced neurotoxicity: modulatory roles of co-morbidity factors and nanoparticle intoxication [0.03%]
脑营养药物脑活素对全身亚高温致神经毒性的神经保护作用：合并因素及纳米颗粒毒性的作用研究
Hari Shanker Sharma,Aruna Sharma,Herbert Mössler et al.
Hari Shanker Sharma et al.
Military personals are often exposed to adverse environmental circumstances, for example, heat stress during peacekeeping or combat operations in summer months or in desert areas leading to disturbed mental functions. The suitable therapeut...
Neurotrophic factors and neurodegenerative diseases: a delivery issue [0.03%]
神经营养因子和神经退行性疾病：一个给药的问题
B Ruozi,D Belletti,L Bondioli et al.
B Ruozi et al.
Neurotrophic factors (NTFs) represent one of the most stimulating challenge in neurodegenerative diseases, due to their potential in neurorestoring and neuroprotection. Despite the large number of proofs-of-concept and evidences of their ac...
Interactions between opioids and anabolic androgenic steroids: implications for the development of addictive behavior [0.03%]
阿片类药物与合成代谢雄性激素之间的相互作用及其对成瘾行为的影响
Fred Nyberg,Mathias Hallberg
Fred Nyberg
Over the past decades, research on doping agents, such as anabolic androgenic steroids (AAS), has revealed that these compounds are often used in combination with other drugs of abuse. It seems that misuse of AAS probably involves more than...
Central nervous tissue damage after hypoxia and reperfusion in conjunction with cardiac arrest and cardiopulmonary resuscitation: mechanisms of action and possibilities for mitigation [0.03%]
心脏停搏及心肺复苏后缺氧再灌注引起中枢神经元损伤的机制及减轻措施的研究进展
Lars Wiklund,Cecile Martijn,Adriana Miclescu et al.
Lars Wiklund et al.
Only approximately 10% of patients encountering a cardiac arrest (CA) and subsequent cardiopulmonary resuscitation survive to a meaningful life. One of the most important causes for this low survival rate is the ischemia-reperfusion injury ...
Environmental conditions modulate neurotoxic effects of psychomotor stimulant drugs of abuse [0.03%]
环境条件调节了兴奋性药物的神经毒性效应
Eugene A Kiyatkin,Hari Shanker Sharma
Eugene A Kiyatkin
Psychomotor stimulants such as methamphetamine (METH), amphetamine, and 3,4-metylenedioxymethamphetamine (MDMA or ecstasy) are potent addictive drugs. While it is known that their abuse could result in adverse health complications, includin...
Quercetin in hypoxia-induced oxidative stress: novel target for neuroprotection [0.03%]
槲皮素在缺氧诱导的氧化应激中的作用：神经保护的新靶点
Anand Kumar Pandey,Ranjana Patnaik,Dafin F Muresanu et al.
Anand Kumar Pandey et al.
Oxidative stress in the central nervous system is one of the key players for neurodegeneration. Thus, antioxidants could play important roles in treating several neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,...
Maria Carolina O Rodrigues,Diana G Hernandez-Ontiveros,Michael K Louis et al.
Maria Carolina O Rodrigues et al.
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with a complicated and poorly understood pathogenesis. Strong evidence indicates impairment of all neurovascular unit components including the blood-brain and blood-s...