Oliver T Mytton,Helen Eyles,David Ogilvie
Oliver T Mytton
Several jurisdictions are now imposing taxes on food and beverages to prevent obesity (and related conditions). Existing evidence concerning their effects comes largely from simulation studies and trials in closed settings, both of which ha...
Solange S Pereira,Jacqueline I Alvarez-Leite
Solange S Pereira
Obesity and its comorbidities are closely related to the inflammatory environment created by expanded adipose tissue. Several mechanisms trigger inflammation in adipose tissue, including excess fatty acids, hypoxia, and activation of the in...
Paul Trayhurn,Jonathan R S Arch
Paul Trayhurn
Brown adipose tissue is specialised for the generation of heat by non-shivering mechanisms. In rodents, the tissue plays a role in energy balance and the development of obesity, as well as in thermoregulation. Studies using fluorodeoxygluco...
Mauro Zamboni,Andrea P Rossi,Francesco Fantin et al.
Mauro Zamboni et al.
In the last decade there has been increasing focus on body fat distribution, rather than on the degree of obesity. More recently, great interest has also been dedicated to ectopic fat deposition in overnourished individuals that reflects a ...
Mouna Zerradi,Julie Dereumetz,Marie-Michèle Boulet et al.
Mouna Zerradi et al.
Androgens are regulators of important adipocyte functions such as adipogenesis, lipid storage, and lipolysis. Through depot-specific impact on the cells of each fat compartment, androgens could modulate body fat distribution patterns in hum...
Impact of Adiposity and Fat Distribution on the Dynamics of Adrenocorticotropin and Cortisol Rhythms [0.03%]
肥胖和脂肪分布对促肾上腺皮质激素和皮质醇节律动态的影响
Ferdinand Roelfsema,Alberto M Pereira,Johannes D Veldhuis
Ferdinand Roelfsema
Obesity impacts many hormonal systems, including pituitary hormones, as well as insulin and leptin. In this review we discuss articles which investigate the influence of obesity on the hypothalamic-pituitary-adrenal (HPA) axis. Different te...
Thomas S Paterakis,Evanthia Diamanti-Kandarakis
Thomas S Paterakis
Women with polycystic ovary syndrome (PCOS), the most common endocrine disorder among women of reproductive age, exhibit an adverse cardiovascular risk profile characteristic of the cardiometabolic syndrome. These women, compared with age- ...
Point-of-Purchase Calorie Labeling Has Little Influence on Calories Ordered Regardless of Body Mass Index [0.03%]
无论体重指数如何，在销售点标出卡路里对所订购的食品热量影响甚微
Sarah Litman Rendell,Charles Swencionis
Sarah Litman Rendell
The obesity epidemic has incited legislation aimed to inform consumers of the nutritional value of food items available in restaurants and fast food establishments, with the presumption that knowing the caloric content in a meal might enabl...
Martin F Casey,Jeffrey I Mechanick
Martin F Casey
Despite the growing market for obesity care, the US Food and Drug Administration (FDA) has approved only two new pharmaceutical agents-lorcaserin and combination phentermine/topiramate-for weight reduction since 2000, while removing three a...
Sarah P Shultz,Nuala M Byrne,Andrew P Hills
Sarah P Shultz
However quantified, obesity is a global health problem of significant magnitude. The condition is no longer limited to the developed world, with an increasing proportion of low-to-middle income countries burdened by obesity and its comorbid...