JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines [0.03%]
JAK2V617F和p53突变同时存在于红白血病和巨核细胞白血病细胞系中
Wanke Zhao,Yanhong Du,Wanting Tina Ho et al.
Wanke Zhao et al.
Background: JAK2V617F, a gain-of-function mutant form of tyrosine kinase JAK2, is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs), a group of chronic hematological diseases that often lead t...
Treatment of splenic marginal zone lymphoma of the CNS with high-dose therapy and allogeneic stem cell transplantation [0.03%]
高强度治疗及异基因干细胞移植治疗中枢神经系统脾边缘区淋巴瘤
Christoph Busemann,Andrej Gudzuhn,Carsten Hirt et al.
Christoph Busemann et al.
Therapy of indolent lymphomas with involvement of the central nervous system (CNS) has not been standardized so far. A 42-year old male patient presented with neurological signs because of leukemic splenic marginal zone lymphoma (SMZL) mani...
Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier [0.03%]
放射治疗与BRCA1突变携带者管腔上皮细胞优先耗竭的关联研究
Huai-Chin Chiang,Sreejith J Nair,I-Tien Yeh et al.
Huai-Chin Chiang et al.
Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of B...
Current management and prognostic features for gastrointestinal stromal tumor (GIST) [0.03%]
胃肠间质瘤(GIST)的当前管理及预后指标特征分析
Gurpreet Lamba,Ridhi Gupta,Byung Lee et al.
Gurpreet Lamba et al.
Stromal or mesenchymal neoplasms affecting the gastrointestinal (GI) tract have undergone a remarkable evolution in how they are perceived, classified, approached, diagnosed and managed over the last 30 years. Gastrointestinal stromal tumor...
R-CHOP with dose-attenuated radiation therapy could induce good prognosis in gastric diffuse large B cell lymphoma [0.03%]
剂量减小的放疗联合R-CHOP方案可使胃弥漫大B细胞淋巴瘤患者获得良好预后
Yuko Mishima,Yasuhito Terui,Masahiro Yokoyama et al.
Yuko Mishima et al.
Background: The treatment strategy for gastric diffuse large cell lymphoma (DLBCL) has not been standardized in such as to the cycles of chemotherapy, dose of radiation, or necessity for the surgery. Although the results ...
Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011 [0.03%]
2004年至2011年匹配的同种异体干细胞移植程序的结果
Natasha Ali,Salman Naseem Adil,Mohammad Usman Shaikh et al.
Natasha Ali et al.
We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HL...
Large granular lymphocytosis with severe neutropenia following ipilimumab therapy for metastatic melanoma [0.03%]
伊匹单抗治疗转移性黑色素瘤后出现严重的中性粒细胞减少伴大颗粒淋巴细胞增多症病例报告
Guoqing Wei,Uzoma Nwakuche,Gustavo Cadavid et al.
Guoqing Wei et al.
Expansion of hematopoietic stem cells for transplantation: current perspectives [0.03%]
造血干细胞移植的扩增：当前的观点
Jessica A Schuster,Maria R Stupnikov,Gina Ma et al.
Jessica A Schuster et al.
Hematopoietic stem cells (HSCs) are rare cells that have the unique ability to self-renew and differentiate into cells of all hematopoietic lineages. The expansion of HSCs has remained an important goal to develop advanced cell therapies fo...
Persistent complete molecular remission after nilotinib and graft-versus-leukemia effect in an acute lymphoblastic leukemia patient with cytogenetic relapse after allogeneic stem cell transplantation [0.03%]
尼洛替尼和移植物抗白血病效应诱导的Ph+急性淋巴细胞白血病移植后遗传学复发患者的持续分子学缓解
Paul Farnsworth,David Ward,Vijay Reddy
Paul Farnsworth
We report the successful treatment and sustained molecular remission using single agent nilotinib in a relapsed Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia patient after allogeneic hematopoietic stem cell transplanta...
Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety [0.03%]
细胞因子诱导的杀伤(CIK)细胞治疗肝细胞癌的疗效和安全性分析
Yue Ma,Ying-Chun Xu,Lei Tang et al.
Yue Ma et al.
Purpose: To evaluate the efficacy of cytokine-induced killer (CIK) cell therapy in the treatment of hepatocellular carcinoma. Materials and methods: ...