JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines
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Background: JAK2V617F, a gain-of-function mutant form of tyrosine kinase JAK2, is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs), a group of chronic hematological diseases that often lead to acute ... ...
