Retraction Notice to: lncRNA ILF3-AS1 promotes proliferation and metastasis of colorectal cancer cells by recruiting histone methylase EZH2 [0.03%]
撤销论文:长链非编码RNA ILF3-AS1通过招募组蛋白甲基转移酶EZH2促进结直肠癌细胞增殖及转移
Sen Hong,Shiquan Li,Miaomiao Bi et al.
Sen Hong et al.
[This retracts the article DOI: 10.1016/j.omtn.2021.04.007.]. © 2023 The Author(s).
Retraction of Publication
Molecular therapy. Nucleic acids. 2023 Jul 12:33:208. DOI:10.1016/j.omtn.2023.07.001 2023
Base editing corrects the common Salla disease SLC17A5 c.115C>T variant [0.03%]
基于编辑可修正最常见的萨拉病SLC17A5 c.115C>T变异
Jerry F Harb,Chloe L Christensen,Shih-Hsin Kan et al.
Jerry F Harb et al.
Free sialic acid storage disorders (FSASDs) result from pathogenic variations in the SLC17A5 gene, which encodes the lysosomal transmembrane protein sialin. Loss or deficiency of sialin impairs FSA transport out of the lysosome, leading to ...
Smooth muscle cell-targeted RNA ligand promotes accelerated reendothelialization in a swine peripheral injury model [0.03%]
平滑肌细胞靶向RNA配体促进猪外周损伤模型加速内皮覆盖
Beilei Lei,Linda B Liu,Lauren Stokes et al.
Beilei Lei et al.
The local delivery of antiproliferative agents to inhibit neointimal growth is not specific to vascular smooth muscle cells (VSMC) and delays reendothelialization and vascular healing. This investigation was intended to evaluate the effect ...
Inhibition of pro-inflammatory signaling in human primary macrophages by enhancing arginase-2 via target site blockers [0.03%]
通过靶向位点阻滞剂增强精氨酸酶-2抑制人原代巨噬细胞中促炎信号通路
Stephen Fitzsimons,María Muñoz-San Martín,Frances Nally et al.
Stephen Fitzsimons et al.
The modulation of macrophage phenotype from a pro-inflammatory to an anti-inflammatory state holds therapeutic potential in the treatment of inflammatory disease. We have previously shown that arginase-2 (Arg2), a mitochondrial enzyme, is a...
Artificial intelligence enabled ChatGPT and large language models in drug target discovery, drug discovery, and development [0.03%]
人工智能赋能的ChatGPT和大型语言模型在药物靶点发现、药物发现与开发中的应用
Chiranjib Chakraborty,Manojit Bhattacharya,Sang-Soo Lee
Chiranjib Chakraborty
RNA nanoparticles for targeted therapies of triple-negative breast cancers [0.03%]
用于三阴性乳腺癌靶向治疗的RNA纳米颗粒
Leyla Danai,Eva Ge,Kirill A Afonin
Leyla Danai
Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer [0.03%]
靶向三阴性乳腺癌细胞的β1整合素结合适配体
Karlis Pleiko,Maarja Haugas,Vadims Parfejevs et al.
Karlis Pleiko et al.
Targeted therapies have increased the treatment options for triple-negative breast cancer patients. However, the paucity of targetable biomarkers and tumor heterogeneity have limited the ability of precision-guided interventions to live up ...
Expression of NORAD correlates with breast cancer aggressiveness and protects breast cancer cells from chemotherapy [0.03%]
NORAD在乳腺癌中的表达与乳腺癌的恶性程度相关并使乳腺癌细胞抵抗化疗药物诱导的杀伤作用
Catarina Alves-Vale,Ana Maria Capela,Carlota Tavares-Marcos et al.
Catarina Alves-Vale et al.
The recently discovered human lncRNA NORAD is induced after DNA damage in a p53-dependent manner. It plays a critical role in the maintenance of genomic stability through interaction with Pumilio proteins, limiting the repression of their t...
The current landscape of long COVID clinical trials: NIH's RECOVER to Stanford Medicine's STOP-PASC initiative [0.03%]
美国长新冠临床试验现状：从NIH的RECOVER到斯坦福医学院的STOP-PASC计划
Chiranjib Chakraborty,Manojit Bhattacharya
Chiranjib Chakraborty