Testosterone Promotes Nerve Tethering and Acellular Biomaterial Perineural Fibrosis in a Rat Wound Repair Model [0.03%]
睾酮通过促进神经缠绕和无细胞生物材料的硬脑膜纤维化从而加重坐骨神经束膜损伤后的继发性损伤(以大鼠为模型)
Calvin R Schuster,Erik Reiche,Patrick R Keller et al.
Calvin R Schuster et al.
Objective: Nerve scarring after traumatic or iatrogenic exposure can lead to impaired function and pain. Nerve-adjacent biomaterials promoting a regenerative tissue response may help reduce perineural fibrosis. Our prior work suggests that ...
Use of Acellular Matrices as Scaffolds in Cartilage Regeneration: A Systematic Review [0.03%]
透明质酸钠注射液用于骨关节炎的镇痛作用：一项随机、双盲、对照研究
Wolfram Demmer,Jannik Schinacher,Paul Severin Wiggenhauser et al.
Wolfram Demmer et al.
Significance: Cartilage regeneration remains a significant challenge in the field of regenerative medicine. Acellular matrix (AM)-based cartilage tissue regeneration offers an innovative approach to repairing cartilage defects by providing ...
Identifying the Pattern Characteristics of Anoikis-Related Genes in Keloid [0.03%]
与外伤相关的瘢痕中anoikis相关基因的模式特征识别
Ruxin Xie,Chenyu Li,Jiao Yun et al.
Ruxin Xie et al.
Objective: Anoikis is a kind of programmed cell death that is triggered when cells lose contact with each other or with the matrix. However, the potential value of anoikis-related genes (ARGs) in keloid (KD) has not been investigated. Appro...
Exploring the Efficacy of Selected Allografts in Chronic Wound Healing: Evidence from Murine Models and Clinical Data for a Proposed Treatment Algorithm [0.03%]
探究选定同种异体移植物在慢性伤口愈合中的疗效：来自小鼠模型和临床数据的证据以及提出的治疗算法
Charlotte R Reed,Tokoya Williams,Iulianna Taritsa et al.
Charlotte R Reed et al.
Significance: Chronic wounds can lead to poor outcomes for patients, with risks, including amputation and death. In the United States, chronic wounds affect 2.5% of the population and cost up to $28 billion per year in primary health care c...
Shannon M Clayton,Sasha H Shafikhani,Athena M Soulika
Shannon M Clayton
Significance: The incidence of diabetes continues to rise throughout the world in an alarming rate. Diabetic patients often develop diabetic foot ulcers (DFUs), many of which do not heal. Non-healing DFUs are a major cause of hospitalizatio...
Assessment of Patient-Reported Outcomes for Closed-Incision Negative Pressure Therapy with Wide-Coverage Dressings in Simple Mastectomy and Immediate Implant-Based Breast Reconstruction [0.03%]
带广泛覆盖敷料的封闭切口负压伤口治疗在乳腺癌保乳术和即刻假体乳房重建术后应用的患者报告结局评估研究
Benjamin G Baker,Andrew Pieri
Benjamin G Baker
Objective: A new configuration of closed-incision negative pressure therapy (ciNPT) dressings now covers the incision and a broader area of peri-incisional tissues. We have implemented these ciNPT dressings following simple mastectomy (SM) ...
Improved Wound Healing by Direct Cold Atmospheric Plasma Once or Twice a Week: A Randomized Controlled Trial on Chronic Venous Leg Ulcers [0.03%]
改善伤口愈合：每周一次或两次直接使用冷等离子体治疗慢性静脉曲张性溃疡的随机对照试验
Olaf Bakker,Paulien Smits,Chantal van Weersch et al.
Olaf Bakker et al.
Objective: This study compared the effect of two frequencies of direct cold atmospheric plasma (direct-CAP) treatment with standard of care (SOC) alone on healing of venous leg ulcers (VLUs). Approach: Open-label, randomized controlled tria...
The Evolution of Commercial Negative Pressure Wound Therapy Systems over the Past Three Decades [0.03%]
过去三十年商用负压伤口治疗系统的演变历程
Cynthia Miller-Mikolajczyk,Karen Beach,Ronald Silverman et al.
Cynthia Miller-Mikolajczyk et al.
Significance: Since the introduction of the first commercial negative pressure wound therapy (NPWT) system nearly three decades ago, several key technological innovations have led to the wide adoption of the therapy. This is a review of the...
Comparative Effectiveness of Negative Pressure Wound Therapy with and Without Oxidized Regenerated Cellulose/Collagen/Silver-ORC Dressing [0.03%]
有关氧化再生纤维素/胶原/银-ORC敷料的负压伤口治疗的比较有效性研究
Yuefeng Hou,Leah Griffin
Yuefeng Hou
Objective: Negative pressure wound therapy (NPWT) and oxidized regenerated cellulose (ORC)/collagen/silver-ORC (OCSO) dressings have individually demonstrated effectiveness in supporting wound healing, but few studies have examined their co...
Chao Cai,Wanqian Li,Xiyue Zhang et al.
Chao Cai et al.
Significance: Acute wounds such as severe burns and chronic wounds like diabetic ulcers present a significant threat to human health. Wound dressings made from natural polymers offer inherent properties that effectively e...