Efficacy and Safety of Human Amniotic Membrane for Chronic Wounds: A Systematic Review and Meta-Analysis of Clinical Trials [0.03%]
人羊膜治疗慢性难愈合创面的疗效和安全性系统评价和 meta 分析
Chengcheng Zheng,Weiwei Tang,Xingwu Ran
Chengcheng Zheng
Objective: The meta-analysis was performed to evaluate the efficacy and safety associated with the application of human amniotic membrane (HAM) in individuals with chronic nonhealing wounds. ...
Immune Imbalance Drives Keloid Pathogenesis: Emerging Targets for Precision Immunotherapy [0.03%]
免疫失衡驱动瘢痕过度增生的机制及精确诊疗靶点
Qilei Chen,Shujun Wan,Yuanyuan Duan et al.
Qilei Chen et al.
Significance: Keloids represent a persistent clinical challenge, with recurrence rates approaching 100% after conventional surgical excision. Historically viewed as fibroblast-driven scars, emerging evidence positions imm...
Efficacy of a Novel Daily-Use Hydrocolloid Pad on Wound Healing: Findings of a 16-Day, Single-Center, Randomized, Controlled Study [0.03%]
新型每日使用的水胶体敷料对伤口愈合疗效的临床研究：一项为期16天的单中心随机对照试验
Jenny Du-Soriano,Diana Friscia,Robert S Kirsner
Jenny Du-Soriano
Objective: To evaluate wound healing with a novel bandage with hydrocolloid pad designed for daily use/replacement in a new model of laser-induced burns/wounds. Approach: In this randomized, controlled, single-center, 16-day study, healthy ...
Dual-Action Topical Therapy Accelerates Healing of MRSA-Infected Burn Wounds by Targeting Infection and Inflammation [0.03%]
一种兼具抗菌和抗炎作用的局部烧伤创面感染治疗手段可加速MRSA感染性难愈合创面的修复
Miaoqing Xiang,Zongze Yao,Wei Shao et al.
Miaoqing Xiang et al.
Objective: Burn injuries affect over 11 million people annually, and methicillin-resistant Staphylococcus aureus (MRSA) infection significantly delays healing by sustaining inflammation and promoting scarring. This study evaluated N-benzyl ...
Shawn Jeffrey Loder,J Peter Rubin
Shawn Jeffrey Loder
Significance: Wound healing is a complex process, and while the epidermis and dermis receive significant attention, the role of the hypodermis is important. The adipose-rich hypodermis or subcutaneous layer supports overall skin function, a...
Comparison of "Semiocclusive Dressing" Treatment Using Plastic Wrap or Low-Adherent Absorbent Wound Dressings Versus Occlusive Dressing Treatment for Stage II Pressure Injuries: A Randomized, Controlled, Noninferiority Trial [0.03%]
塑料薄膜与低粘性吸水性敷料作为半封闭敷料治疗II期压力性损伤与完全封闭式敷料的比较：随机对照非劣效性试验
Jun Takahashi,Kayoko Nakae,Osamu Yokota et al.
Jun Takahashi et al.
Objective: To verify the noninferiority of the effectiveness of "semiocclusive dressing" (SOD) treatment using plastic wrap or low-adherent absorbent wound dressings compared with occlusive dressing (OD) treatment for National Pressure Inju...
Christopher V Lavin,Carter B Kendig,Danae Kawamoto et al.
Christopher V Lavin et al.
Significance: Wound healing in irradiated skin remains a clinical challenge, with radiation therapy (XRT) resulting in excess collagen deposition and cell death resulting in poor tissue quality. This frequently results in chronic wounds tha...
Nurse Staffing and Patient Outcomes: A Call to Action for Chronic Wound Care Policy Reform [0.03%]
护士人力配置与病人护理结果：慢性伤口护理政策改革任重道远
Eleanor Turi,Karen B Lasater,K Jane Muir
Eleanor Turi
Objective: Patients with complex chronic wounds are at high risk for poor outcomes. This study assessed the relationship between nurse staffing and outcomes among patients with complex and noncomplex chronic wounds. [Figure: see text] Appro...
Long-Term Efficacy of Guideline-Followed Treatment in Patients with Livedoid Vasculopathy: A Single-Center Study [0.03%]
循证治疗雷诺五联征长期疗效观察：单中心研究
Carina Hillgruber,Carolin Mitschang,Maria Eveslage et al.
Carina Hillgruber et al.
Objective: Livedoid vasculopathy is a skin disease characterized by recurrent painful ulcerations of the lower leg leading to scar formation (atrophie blanche). Ulceration results from thrombosis of the cutaneous microcirculation and is oft...
Clinical Features and Mechanisms of Differential Wound Healing and Scarring Across Anatomical Sites [0.03%]
解剖位置特异的伤口愈合和瘢痕形成的临床特征及机制
Hanqi Yao,Serena L Jing,Kelly X Huang et al.
Hanqi Yao et al.
Significance: Fibrosis is associated with high rates of morbidity and mortality and poses a heavy burden on the health care system. Different regions of the body heal at different rates with varying degrees of fibrosis, with regions such as...