SNaP® Wound Care System: Ultraportable Mechanically Powered Negative Pressure Wound Therapy [0.03%]
SNaP®伤口护理系统：便携式机械驱动的负压伤口治疗装置
Kenton D Fong,William A Marston
Kenton D Fong
Problem: Negative pressure wound therapy (NPWT) is a well-accepted modality for treatment of difficult wounds, but has traditionally required a bulky electrically powered pump that was difficult to procure and use for bot...
Gerrit Grieb,Richard Bucala
Gerrit Grieb
Background: First described in 1994, fibrocytes are now appreciated to participate in different inflammatory and fibrogenic processes as well as in wound healing. Fibrocytes are unique in their expression of both myeloid ...
Stress-Induced Hormones Cortisol and Epinephrine Impair Wound Epithelization [0.03%]
应激激素皮质醇和肾上腺素抑制伤口表皮化作用
Olivera Stojadinovic,Katherine A Gordon,Elizabeth Lebrun et al.
Olivera Stojadinovic et al.
Background: Stress-induced disruption of hormonal balance in animals and humans has a detrimental effect on wound healing. The problem: ...
Carole A Oskeritzian
Carole A Oskeritzian
Background: Mast cells (MC) are ubiquitous resident cells, traditionally viewed as effector cells of allergic reactions that can store and synthesize de novo many mediators upon activation by a variety of stimuli. Excitin...
Wound Healing Angiogenesis: Innovations and Challenges in Acute and Chronic Wound Healing [0.03%]
创伤愈合血管生成：急性期和慢性期伤口愈合的创新与挑战
Tatiana N Demidova-Rice,Jennifer T Durham,Ira M Herman
Tatiana N Demidova-Rice
Background: Formation of new blood vessels, by either angiogenesis or vasculogenesis, is critical for normal wound healing. Major processes in neovascularization include (i) growth-promoting or survival factors, (ii) prot...
Christopher J Ferrante,Samuel Joseph Leibovich
Christopher J Ferrante
Background: Macrophages (Mφs) participate in wound healing by coordinating inflammatory and angiogenic processes. Mφs respond to environmental cues by adopting either "classically" activated (M1) proinflammatory or "alt...
H Paul Ehrlich,Thomas K Hunt
H Paul Ehrlich
Background: Open wound closure by wound contraction produces a healed defect made up mostly of dermis. Generating thicker collagen fibers condenses granulation tissue, which pulls surrounding skin into the defect. ...