The Role of Mesenchymal Stem Cells in the Regenerative Wound Healing Phenotype [0.03%]
间充质干细胞在再生型伤口愈合中的作用
Swathi Balaji,Sundeep G Keswani,Timothy M Crombleholme
Swathi Balaji
Background: Mesenchymal stem cells (MSCs) are key to regenerative wound healing. MSCs have spatial memory and respond to local environment. MSCs orchestrate wound repair by: (1) structural repair via cellular differentiat...
Summer E Hanson
Summer E Hanson
Background: Although significant resources are invested in wound care and healing annually, chronic wounds remain a major medical problem as they often present a more difficult challenge than the underlying disease. Curre...
Kristine C Rustad,Geoffrey C Gurtner
Kristine C Rustad
Background: Mesenchymal stem cells (MSCs) have shown significant therapeutic potential in preclinical animal models of wound healing. However, the translation of MSC-based therapeutics to clinical practice has been delaye...
SensiLase Studycast System: A Platform for Critical Limb Diagnostics and Electronic Referral Program [0.03%]
SensiLase Studycast系统：一种关键肢体诊断和电子转诊平台
Thomas Serena
Thomas Serena
Problem: Peripheral arterial disease (PAD) and critical limb ischemia (CLI) impede lower extremity wound healing. The highest-risk patient populations have foot ulcers, ischemic disease, diabetes mellitus, and/or compromi...
Charles E Hart,Andrea Loewen-Rodriguez,Jan Lessem
Charles E Hart
Problem: Lower limb ulceration is a common problem in clinical practice. A variety of metabolic and physical causes can lead to a diversity of chronic ulcer types, including diabetic foot ulcers (DFUs) and venous leg ulce...
Education in Wound Management in Europe with a Special Focus on the Danish Model [0.03%]
欧洲伤口护理教育——以丹麦模式为重点
Finn Gottrup
Finn Gottrup
Background: Standardized education and training programs are fundamental for the establishment of a healthcare structure within wound management. The prob...
Christopher Attinger,Randy Wolcott
Christopher Attinger
Background: A chronic wound is a wound that is arrested in the inflammatory phase of wound healing and cannot progress further. Over 90% of chronic wounds contain bacteria and fungi living within a biofilm construct. ...
Curtis E Jones,John P Kennedy
Curtis E Jones
Background: Bioburden is an accepted barrier to chronic wound healing. Defining the significance, phenotype, clinical classification, and treatment guidelines has been historically lacking of evidence and based on paradig...
Owatha L Tatum,Scot E Dowd
Owatha L Tatum
Background: Many wounds are difficult to heal because of the large, complex community of microbes present within the wound. The problem: ...
Priscilla L Phillips,Gregory S Schultz
Priscilla L Phillips
Background: Numerous planktonic virulence factors have been identified that enable bacteria to successfully produce acute infections in tissues. In contrast, very little is known about biofilm virulence factors that enhan...