The role of hydrogels biomaterials in the intervention of wound healing and skin regeneration via exosomes: a systematic review and meta-analysis of preclinical animal studies [0.03%]
水凝胶生物材料通过外泌体干预伤口愈合和皮肤再生的预临床动物研究系统评价和meta分析
Yujia Yang,Jinlei Cui,Yajie Kong et al.
Yujia Yang et al.
Significance: The combination of hydrogel biomaterials with exosomes to facilitate wound healing and skin regeneration is a promising approach. Recent adv...
Comparison of "Semiocclusive Dressing" Treatment Using Plastic Wrap or Low-Adherent Absorbent Wound Dressings Versus Occlusive Dressing Treatment for Stage III/IV Pressure Injuries in the Inflammatory Phase: A Randomized Controlled Trial [0.03%]
塑料薄膜与低粘性吸收敷料作为半封闭敷料治疗重度压力性损伤炎症期与完全封闭敷料的比较：随机对照试验
Jun Takahashi,Kayoko Nakae,Osamu Yokota et al.
Jun Takahashi et al.
Objective: To compare the effectiveness of "semiocclusive dressing (SOD)" treatment using plastic wrap or low-adherent absorbent wound dressings with that of occlusive dressing (OD) treatment for National Pressure Injury Advisory Panel stag...
Dynamic prediction of time to wound healing at routine wound care visits [0.03%]
基于常规伤口护理随访的伤口愈合时间动态预测模型
Doranne Thomassen,Stella Felicia Amesz,Niels Philip Stol et al.
Doranne Thomassen et al.
Objective Having a wound decreases patients' quality of life and brings uncertainty, especially if the wound does not show a healing tendency. The objective of this study was to develop and validate a model to dynamically predict time to wo...
Counting the Cost of Cellular and/or Tissue-Based Products in Diabetic Foot Ulcers: Is There a Justifiable Price Limit per Square Centimeter? [0.03%]
糖尿病足溃疡中基于细胞和/或组织产品的治疗成本有多大？每平方厘米是否有合理的定价限度？
Marissa J Carter,Caroline E Fife
Marissa J Carter
Objective: To identify how cellular and/or tissue-based products (CTPs) relate to value in terms of cost per quality-adjusted life years (QALYs) in wound care in comparison with treatments in other medical fields. Approach: This is a cross-...
Effects of ON101 for Hard-to-Heal Diabetic Foot Ulcers in A Randomized Phase III Trial: A Post hoc Analysis [0.03%]
一种针对难治性糖尿病足溃疡药物ON101的三期临床试验的事后分析
Shun-Cheng Chang,Ching-Wen Lin,Jui-Ching Chen et al.
Shun-Cheng Chang et al.
Objective: Hard-to-heal diabetic foot ulcers (DFUs) are associated with higher mortality rates and an increased medical burden for patients. ON101, a new topical cream, exhibited better healing efficacy than the control d...
New Opportunities for Electric Fields in Promoting Wound Healing: Collective Electrotaxis [0.03%]
电场促进伤口愈合的新机遇：集体静电感应迁移现象
Yan Zhang,Shiwen Huang,Yifei Cao et al.
Yan Zhang et al.
Significance: It has long been hypothesized that naturally occurring electric fields (EFs) aid wound healing by guiding cell migration. Consequently, the application of EFs has significant potential for promoting wound healing. However, the...
A First-in-Human Randomized Clinical Study Investigating the Safety and Tolerability of Stabilized Hypochlorous Acid in Patients with Chronic Leg Ulcers [0.03%]
关于次氯酸在慢性腿部溃疡患者中安全性和耐受性的首次人体随机临床研究
Magnus Mustafa Fazli,Klaus Kirketerp-Møller,David Peick Sonne et al.
Magnus Mustafa Fazli et al.
Objective: Biofilm infections in chronic wounds are common and pose a significant clinical challenge. This challenge was addressed by developing the SoftOx Biofilm Eradicator (SBE) composed of hypochlorous acid (HOCl) and acetic acid with s...
Systematic Review of Cellular, Acellular, and Matrix-like Products and Indirect Treatment Comparison Between Cellular/Acellular and Amniotic/Nonamniotic Grafts in the Management of Diabetic Foot Ulcers [0.03%]
有关细胞型、非细胞型和类似基质型产品治疗糖尿病足溃疡的间接比较及系统评价
Jaideep Banerjee,Andrew Lasiter,Leo Nherera
Jaideep Banerjee
Significance: This Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-compliant review focuses on the efficacy of cellular, acellular, and matrix-like products (CAMPs) in the management of diabetic foot ulcers (DFUs...
The WOUND-Q Function and Symptoms Scales for Chronic Lower Extremity Wounds: A Validation Study [0.03%]
慢性下肢难愈合创面WOUND-Q功能和症状量表的验证性研究
Nina Vestergaard Simonsen,Anne F Klassen,Charlene Rae et al.
Nina Vestergaard Simonsen et al.
Objective: Determine the validity and reliability of the LIMB-Q scales, Function, and Symptoms in patients with chronic lower extremity wounds. Approach: Cognitive debriefing interviews with people with current or previous wounds were condu...
Biomaterial-Based Regenerative Strategies for Volumetric Muscle Loss: Challenges and Solutions [0.03%]
基于生物材料的体积性肌肉损失再生策略：挑战与解决方案
Charlene W Cai,Josh A Grey,Dirk Hubmacher et al.
Charlene W Cai et al.
Significance: Volumetric muscle loss (VML) is caused by the loss of significant amounts of skeletal muscle tissue. VML cannot be repaired by intrinsic regenerative processes, resulting in permanent loss of muscle function and disability. Cu...