Kedi Xu,Kyle R Kleinbeck,Weiyuan John Kao
Kedi Xu
Background: Modern wound dressings provide a moist healing environment and facilitate faster and higher quality of healing. A new semi-interpenetrating network (sIPN) biomaterial platform based on poly(ethylene glycol) (P...
Morphogenesis and Biomechanics of Engineered Skin Cultured Under Uniaxial Strain [0.03%]
单轴拉伸培养的皮肤组织的形态发生及生物力学性质研究
Britani N Blackstone,Heather M Powell
Britani N Blackstone
Background: Split-thickness autograft is the standard wound treatment for full-thickness burns. In large burns, sparse availability of uninjured skin prevents rapid closure of the wound, resulting in increased scar tissue...
Genomic Reprogramming and Skin-Like Maturation of Engineered Human Skin Substitutes [0.03%]
重组基因组再编程及皮肤成熟工程人类皮肤替代物
Dorothy M Supp
Dorothy M Supp
Background: Cultured skin substitutes (CSS) have been evaluated in clinical trials as an adjunctive treatment for large full-thickness burn wounds. Prepared with autologous fibroblasts, keratinocytes, and biopolymers, CSS...
Chimeric Human Skin Substitute Tissue: A Novel Treatment Option for the Delivery of Autologous Keratinocytes [0.03%]
人源嵌合皮肤替代组织：自体角质形成细胞移植的新选择
Cathy A Rasmussen,B Lynn Allen-Hoffmann
Cathy A Rasmussen
Background: For patients suffering from catastrophic burns, few treatment options are available. Chimeric coculture of patient-derived autologous cells with a "carrier" cell source of allogeneic keratinocytes has been pro...
Cascade® Autologous System Platelet-Rich Fibrin Matrix in the Treatment of Chronic Leg Ulcers [0.03%]
Cascade 自体系统富血小板纤维蛋白矩阵治疗慢性腿溃疡
Sean M O&#x;Connell,Karen Hessler,Herbert Dardik
Sean M O&#x;Connell
Problem: Lower extremity ulcers (venous, diabetic) are often unresponsive to standard treatment. Various systemic and local cellular, vascular, and anatomical factors can result in nonhealing wounds that are refractory to...
Edward I Stout,Angie McKessor
Edward I Stout
Problem: Infection is a major problem in the health and wellbeing of patients in hospitals, nursing homes, and other medical facilities as well as the homecare patients and the general public. According to Scientia Adviso...
PolyMem® Wic® Silver® Rope: A Multifunctional Dressing for Decreasing Pain, Swelling, and Inflammation [0.03%]
PolyMem Wic Silver绳状敷料：一种能减少疼痛、肿胀和炎症的多功能敷料
Linda L L Benskin
Linda L L Benskin
Problem: Choosing the most appropriate dressing to meet the complex needs of patients with narrow deep wounds, such as tunnels, fistulas, and cysts, is a daunting task. Such wounds are difficult to cleanse and tend to be ...
SNaP® Wound Care System: Ultraportable Mechanically Powered Negative Pressure Wound Therapy [0.03%]
SNaP®伤口护理系统：便携式机械驱动的负压伤口治疗装置
Kenton D Fong,William A Marston
Kenton D Fong
Problem: Negative pressure wound therapy (NPWT) is a well-accepted modality for treatment of difficult wounds, but has traditionally required a bulky electrically powered pump that was difficult to procure and use for bot...
Gerrit Grieb,Richard Bucala
Gerrit Grieb
Background: First described in 1994, fibrocytes are now appreciated to participate in different inflammatory and fibrogenic processes as well as in wound healing. Fibrocytes are unique in their expression of both myeloid ...
Stress-Induced Hormones Cortisol and Epinephrine Impair Wound Epithelization [0.03%]
应激激素皮质醇和肾上腺素抑制伤口表皮化作用
Olivera Stojadinovic,Katherine A Gordon,Elizabeth Lebrun et al.
Olivera Stojadinovic et al.
Background: Stress-induced disruption of hormonal balance in animals and humans has a detrimental effect on wound healing. The problem: ...