Charles E Hart,Andrea Loewen-Rodriguez,Jan Lessem
Charles E Hart
Problem: Lower limb ulceration is a common problem in clinical practice. A variety of metabolic and physical causes can lead to a diversity of chronic ulcer types, including diabetic foot ulcers (DFUs) and venous leg ulce...
Education in Wound Management in Europe with a Special Focus on the Danish Model [0.03%]
欧洲伤口护理教育——以丹麦模式为重点
Finn Gottrup
Finn Gottrup
Background: Standardized education and training programs are fundamental for the establishment of a healthcare structure within wound management. The prob...
Christopher Attinger,Randy Wolcott
Christopher Attinger
Background: A chronic wound is a wound that is arrested in the inflammatory phase of wound healing and cannot progress further. Over 90% of chronic wounds contain bacteria and fungi living within a biofilm construct. ...
Curtis E Jones,John P Kennedy
Curtis E Jones
Background: Bioburden is an accepted barrier to chronic wound healing. Defining the significance, phenotype, clinical classification, and treatment guidelines has been historically lacking of evidence and based on paradig...
Owatha L Tatum,Scot E Dowd
Owatha L Tatum
Background: Many wounds are difficult to heal because of the large, complex community of microbes present within the wound. The problem: ...
Priscilla L Phillips,Gregory S Schultz
Priscilla L Phillips
Background: Numerous planktonic virulence factors have been identified that enable bacteria to successfully produce acute infections in tissues. In contrast, very little is known about biofilm virulence factors that enhan...
Jenny Hurlow
Jenny Hurlow
Problem: There are many silver-containing wound dressings available for managing and preventing wound infection. Each claims to provide effective antimicrobial activity due to the presence of silver in the dressing. Howev...
Clinical Evaluation of NIKS-Based Bioengineered Skin Substitute Tissue in Complex Skin Defects: Phase I/IIa Clinical Trial Results [0.03%]
基于NIKS的生物工程皮肤移植物治疗复杂皮肤缺损的临床评价：I/IIa期临床试验结果
Michael J Schurr,Kevin N Foster,Mary A Lokuta et al.
Michael J Schurr et al.
Background: Complex skin defects, such as burns and acute cutaneous trauma, are life-threatening injuries, often requiring temporary allograft placement to maintain fluid homeostasis and prevent infection until permanent ...
Christina L Thomas-Virnig,B Lynn Allen-Hoffmann
Christina L Thomas-Virnig
Background: Complex skin defects resulting from acute skin trauma and chronic, nonhealing wounds are life-threatening injuries. Infection is one of the most common obstacles to the healing of these types of wounds. Host d...
Electric Potential Across Epidermis and Its Role During Wound Healing Can Be Studied by Using an In Vitro Reconstructed Human Skin [0.03%]
体外重建的人造皮肤可用于研究表皮电位及其在伤口愈合过程中的作用
Véronique J Moulin,Jean Dubé,Olivier Rochette-Drouin et al.
Véronique J Moulin et al.
Background: After human epidermis wounding, transepithelial potential (TEP) present in nonlesional epidermis decreases and induces an endogenous direct current epithelial electric field (EEF) that could be implicated in t...