Michael J Sherratt
Michael J Sherratt
Significance: Tissue elasticity is severely compromised in aging skin, lungs, and blood vessels. In the vascular and pulmonary systems, respectively, loss of mechanical function is linked to hypertension, which in turn is...
Miranda A Farage,Kenneth W Miller,Peter Elsner et al.
Miranda A Farage et al.
Significance: Although most researches into the changes in skin with age focus on the unwelcome aesthetic aspects of the aging skin, skin deterioration with age is more than a merely cosmetic problem. Although mortality f...
Preclinical Models of Wound Healing: Is Man the Model? Proceedings of the Wound Healing Society Symposium [0.03%]
wounds healing：人类是研究模型吗？美国伤口愈合学会专题讨论会论文集
Gayle M Gordillo,Stephanie F Bernatchez,Robert Diegelmann et al.
Gayle M Gordillo et al.
Significance: A review of therapeutic effects in preclinical and clinical studies suggests that concordance between large animal (pig=78%), small laboratory animal (53%) and in vitro (57%) results with those observed in h...
3M Coban 2 Layer Compression Therapy: Intelligent Compression Dynamics to Suit Different Patient Needs [0.03%]
3M Coban 2层弹力绷带治疗：智能压力动力学适应不同患者需求
Jan Schuren,Stéphanie F Bernatchez,Joseph Tucker et al.
Jan Schuren et al.
Problem: Chronic venous insufficiency can lead to recalcitrant leg ulcers. Compression has been shown to be effective in healing these ulcers, but most products are difficult to apply and uncomfortable for patients, leadi...
Traci A Wilgus
Traci A Wilgus
Background: Wound healing is a process made up of several phases, including hemostasis/inflammation, proliferation, and scar formation/remodeling. An array of growth factors is produced during each of these phases that he...
Arthur C Huen,Alan Wells
Arthur C Huen
Background: Prior to 2009, research regarding the role of CXC receptor 3 (CXCR3) in cutaneous biology was primarily in the context of inflammatory reactions. Foundational research performed at that time demonstrated that,...
R Rivkah Isseroff,Sara E Dahle
R Rivkah Isseroff
Background: Healing chronic wounds is an ongoing challenge for clinicians and poses a serious public health burden. Electrical stimulation (ES), broadly defined as the application of electrical current via electrodes plac...
A Molecular Link Between Interleukin 22 and Intestinal Mucosal Wound Healing [0.03%]
关于白细胞介素-22和肠黏膜伤口愈合的分子联系
Xiaoyan Sun,Laura Chalmers,Xiaobing Fu et al.
Xiaoyan Sun et al.
Background: Interleukin 22 (IL-22) and signal transducer and activator of transcription 3 (STAT3) are two important regulators of inflammation. Crohn's disease and ulcerative colitis are considered inflammatory bowel dise...
Diego M Castilla,Zhao-Jun Liu,Omaida C Velazquez
Diego M Castilla
Background: Oxygen is vital for healing wounds. It is intricately involved in numerous biological processes including cell proliferation, angiogenesis, and protein synthesis, which are required for restoration of tissue f...
John Layliev,Stelios Wilson,Stephen M Warren et al.
John Layliev et al.
Background: Impaired wound healing remains a major clinical problem with many etiologies. Altering gene expression to enhance healing is an innovative therapeutic approach. In recent years, we have developed a means to to...