Sadanori Akita,Kozo Akino,Akiyoshi Hirano
Sadanori Akita
Significance: The benefit and role of basic fibroblast growth factor (bFGF) in scarless wound healing in clinical application and basic mechanism are discussed. bFGF is a glycoprotein which is widely used in treating woun...
David T Corr,David A Hart
David T Corr
Significance: Skin exhibits direction-dependent biomechanical behavior, influenced by the structural orientation of its collagen-rich fibrous network and its viscous ground-substance matrix. Injury can affect the skin's s...
Marissa Janine Carter
Marissa Janine Carter
Objective: To describe the role of health economics (HE) in wound care in relation to coverage and reimbursement. Approach: Narrative d...
Benjamin J Brown,Christopher E Attinger
Benjamin J Brown
Significance: A below-knee amputation (BKA) can be the most functional option for select patients with a diseased lower extremity and may offer a better quality of life than limb salvage in some patients. ...
Epidermal Growth Factor and Epidermal Growth Factor Receptor: The Yin and Yang in the Treatment of Cutaneous Wounds and Cancer [0.03%]
表皮生长因子和表皮生长因子受体在创面修复与肿瘤治疗中的双刃剑作用机制：阴阳相济，刚柔并举
Richard J Bodnar
Richard J Bodnar
Significance: Epidermal growth factor (EGF) and EGF receptor (EGFR) play an essential role in wound healing through stimulating epidermal and dermal regeneration. The development of new therapies for enhancing wound heali...
Daniel J Gibson,Gregory S Schultz
Daniel J Gibson
Significance: The process of wound healing includes the regulated destruction of proteins via enzymes called proteinases. However, when the proteolytic process becomes excessive, pro-healing factors are destroyed and the ...
Michael J Sherratt
Michael J Sherratt
Significance: Tissue elasticity is severely compromised in aging skin, lungs, and blood vessels. In the vascular and pulmonary systems, respectively, loss of mechanical function is linked to hypertension, which in turn is...
Miranda A Farage,Kenneth W Miller,Peter Elsner et al.
Miranda A Farage et al.
Significance: Although most researches into the changes in skin with age focus on the unwelcome aesthetic aspects of the aging skin, skin deterioration with age is more than a merely cosmetic problem. Although mortality f...
Preclinical Models of Wound Healing: Is Man the Model? Proceedings of the Wound Healing Society Symposium [0.03%]
wounds healing：人类是研究模型吗？美国伤口愈合学会专题讨论会论文集
Gayle M Gordillo,Stephanie F Bernatchez,Robert Diegelmann et al.
Gayle M Gordillo et al.
Significance: A review of therapeutic effects in preclinical and clinical studies suggests that concordance between large animal (pig=78%), small laboratory animal (53%) and in vitro (57%) results with those observed in h...
3M Coban 2 Layer Compression Therapy: Intelligent Compression Dynamics to Suit Different Patient Needs [0.03%]
3M Coban 2层弹力绷带治疗：智能压力动力学适应不同患者需求
Jan Schuren,Stéphanie F Bernatchez,Joseph Tucker et al.
Jan Schuren et al.
Problem: Chronic venous insufficiency can lead to recalcitrant leg ulcers. Compression has been shown to be effective in healing these ulcers, but most products are difficult to apply and uncomfortable for patients, leadi...