Michael Januszyk,Geoffrey C Gurtner
Michael Januszyk
Significance: Wound repair is a complex biological process that integrates multiple physiologic pathways to restore skin homeostasis after a wide array of gross and anatomical insults. As such, a scientific examination of...
Asheesh Gupta,Pinar Avci,Tianhong Dai et al.
Asheesh Gupta et al.
Significance: Wound care is an important area of medicine considering the increasing age of the population who may have diverse comorbidities. Light-based technology comprises a varied set of modalities of increasing rele...
Dynamic Regulation of Integrin α6β4 During Angiogenesis: Potential Implications for Pathogenic Wound Healing [0.03%]
角蛋白5/14阳性细胞在血管生成过程中的动态调节及其对病理性伤口修复的潜在影响
Diana Desai,Purva Singh,Livingston Van De Water et al.
Diana Desai et al.
Objective: Angiogenesis is an essential component of normal cutaneous wound repair, but is altered in pathogenic forms of wound healing, such as chronic wounds and fibrosis. We previously reported that endothelial express...
Ge Zhao,Marcia L Usui,Soyeon I Lippman et al.
Ge Zhao et al.
Significance: The incidence, cost, morbidity, and mortality associated with non-healing of chronic skin wounds are dramatic. With the increasing numbers of people with obesity, chronic medical conditions, and an increasin...
Traci A Wilgus,Sashwati Roy,Jodi C McDaniel
Traci A Wilgus
Significance: Neutrophils are one of the most abundant cells of the immune system and they are extremely active during the repair of cutaneous wounds. In general, the antimicrobial activity of neutrophils is effective and...
Cardiac Progenitor Cells in Myocardial Infarction Wound Healing: A Critical Review [0.03%]
心肌梗死伤口愈合中心肌祖细胞的研究：批判性综述
Michael W Morris Jr,Kenneth W Liechty
Michael W Morris Jr
Significance: Coronary artery disease is a major cause of morbidity and mortality as the loss of functional myocardium drives progressive ventricular remodeling and subsequent heart failure. Medical management has signifi...
M Noelle Knight,Kurt D Hankenson
M Noelle Knight
Significance: Mesenchymal stem cells (MSCs) play a key role in fracture repair by differentiating to become bone-forming osteoblasts and cartilage-forming chondrocytes. Cartilage then serves as a template for additional b...
Ruoxue Feng,Chistopher Lengner
Ruoxue Feng
Significance: In this review, we summarize the current literature regarding the isolation and characterization of dental tissue-derived stem cells and address the potential of these cell types for use in regenerative cell...
The Role of Endothelial Progenitor Cells in Postnatal Vasculogenesis: Implications for Therapeutic Neovascularization and Wound Healing [0.03%]
内皮祖细胞在出生后血管生成中的作用及其对治疗性新生血管和伤口愈合的意义
Swathi Balaji,Alice King,Timothy M Crombleholme et al.
Swathi Balaji et al.
Significance: Postnatal vasculogenesis mediated via endothelial progenitor cells (EPCs) contributes to re-endothelialization and augments neovascularization after ischemia and tissue injury, providing a novel therapeutic ...
Makoto Senoo
Makoto Senoo
Significance: The skin interfollicular epidermis (IFE) is an organism's first line of defense against a harmful environment and physical damage. During homeostasis and wound repair, the IFE is rejuvenated constantly by IF...